P67080 (YGGS_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
UPF0001 protein yggS

Gene names

Name:	yggS
Ordered Locus Names:	b2951, JW2918

Organism

Escherichia coli (strain K12)

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	234 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Cofactor	Pyridoxal phosphate By similarity.
Sequence similarities	Belongs to the UPF0001 family.

Ontologies

Keywords
Ligand	Pyridoxal phosphate
Technical term	3D-structure Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	pyridoxal phosphate binding Inferred from sequence or structural similarity. Source: RefGenome
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 234

234

UPF0001 protein yggS

PRO_0000163196

Amino acid modifications

Modified residue

36

1

N6-(pyridoxal phosphate)lysine By similarity

Secondary structure

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234

Helix Strand Turn

Details...

Helix

4 – 21

18

Helix

26 – 28

3

Beta strand

30 – 34

5

Helix

40 – 48

9

Beta strand

53 – 58

6

Helix

59 – 71

13

Beta strand

78 – 81

4

Helix

87 – 89

3

Helix

90 – 96

7

Beta strand

98 – 103

6

Helix

106 – 115

10

Beta strand

123 – 129

7

Helix

142 – 144

3

Helix

145 – 153

9

Beta strand

158 – 165

8

Helix

173 – 193

21

Beta strand

199 – 201

3

Helix

205 – 207

3

Helix

208 – 214

7

Beta strand

217 – 222

6

Helix

223 – 226

4

Sequences

	Sequence		Length	Mass (Da)
	P67080 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: 2AA431E2D75BCA59	FASTA	234	25,787
	10 20 30 40 50 60 MNDIAHNLAQ VRDKISAAAT RCGRSPEEIT LLAVSKTKPA SAIAEAIDAG QRQFGENYVQ 70 80 90 100 110 120 EGVDKIRHFQ ELGVTGLEWH FIGPLQSNKS RLVAEHFDWC HTIDRLRIAT RLNDQRPAEL 130 140 150 160 170 180 PPLNVLIQIN ISDENSKSGI QLAELDELAA AVAELPRLRL RGLMAIPAPE SEYVRQFEVA 190 200 210 220 230 RQMAVAFAGL KTRYPHIDTL SLGMSDDMEA AIAAGSTMVR IGTAIFGARD YSKK

References

[1]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed: 9278503] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[2]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed: 16738553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

U28377 Genomic DNA. Translation: AAA69118.1.
U00096 Genomic DNA. Translation: AAC75988.1.
AP009048 Genomic DNA. Translation: BAE77014.1.

PIR

F65080.

RefSeq

NP_417426.1. NC_000913.2.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1W8G	X-ray	2.00	A	1-234	[»]
3SY1	X-ray	1.46	A	1-234	[»]

ProteinModelPortal

P67080.

SMR

P67080. Positions 3-228.

ModBase

Search...

Protein-protein interaction databases

IntAct

P67080. 8 interactions.

MINT

MINT-1236179.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

EBESCT00000002429; EBESCP00000002429; EBESCG00000001978.
EBESCT00000017704; EBESCP00000016995; EBESCG00000016760.

GeneID

947423.

GenomeReviews

Gene locus JW2918 in contig AP009048_GR.
Gene locus b2951 in contig U00096_GR.

KEGG

ecj:JW2918.
eco:b2951.

PATRIC

32121314. VBIEscCol129921_3045.

Organism-specific databases

EchoBASE

EB2804.

EcoGene

EG12979. yggS.

Phylogenomic databases

eggNOG

COG0325.

GeneTree

EBGT00050000011688.

HOGENOM

HBG289671.

OMA

HGSTMVR.

PhylomeDB

P67080.

ProtClustDB

CLSK880540.

Enzyme and pathway databases

BioCyc

EcoCyc:G7527-MONOMER.

Gene expression databases

Genevestigator

P67080.

Family and domain databases

InterPro

IPR001608. Ala_racemase_N.
IPR011078. UPF0001.
[Graphical view]

KO

K06997.

PANTHER

PTHR10146. PP_YBL036C. 1 hit.

Pfam

PF01168. Ala_racemase_N. 1 hit.
[Graphical view]

PIRSF

PIRSF004848. YBL036c_PLPDEIII. 1 hit.

TIGRFAMs

TIGR00044. TIGR00044. 1 hit.

PROSITE

PS01211. UPF0001. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

YGGS_ECOLI

Accession

Primary (citable) accession number: P67080
Secondary accession number(s): P52054, Q2M9P2

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 11, 2004
Last sequence update:	October 11, 2004
Last modified:	January 25, 2012
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program