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P67003

- TRPF_BRUME

UniProt

P67003 - TRPF_BRUME

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Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene

trpF

Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciBMEL224914:GCJ0-2064-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotation (EC:5.3.1.24UniRule annotation)
Short name:
PRAIUniRule annotation
Gene namesi
Name:trpFUniRule annotation
Ordered Locus Names:BMEI2017
OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Taxonomic identifieri224914 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000000419: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 222222N-(5'-phosphoribosyl)anthranilate isomerasePRO_0000154348Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi224914.BMEI2017.

Structurei

3D structure databases

ProteinModelPortaliP67003.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000161598.
KOiK01817.
OMAiDILQLHG.
OrthoDBiEOG6N94DF.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

P67003-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MALDIKICGL KTPEAVAAAL DGGATHIGFI FFPKSPRHIT PDAAARLRAA
60 70 80 90 100
ATGRAVAVAV TVDADDEALD EIVKTVRPDM LQLHGGETPE RVRFLKERYN
110 120 130 140 150
LPVMKAFSIR EAGDLEAIAP YRGIADRFLF DAKPPKGSEL PGGNGISFDW
160 170 180 190 200
NLLAALDADI DYMLSGGLNA DNIAEALLKT GAPGIDISSG VECAPGEKDV
210 220
RLIENFFQAV ADANAQPFAR RA
Length:222
Mass (Da):23,614
Last modified:October 11, 2004 - v1
Checksum:i28E7AFA3258F5514
GO

Sequence cautioni

The sequence AAL53198.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008917 Genomic DNA. Translation: AAL53198.1. Different initiation.
PIRiAC3504.
RefSeqiNP_540934.1. NC_003317.1.

Genome annotation databases

EnsemblBacteriaiAAL53198; AAL53198; BMEI2017.
GeneIDi1197728.
KEGGibme:BMEI2017.
PATRICi17854486. VBIBruMel92729_2226.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008917 Genomic DNA. Translation: AAL53198.1 . Different initiation.
PIRi AC3504.
RefSeqi NP_540934.1. NC_003317.1.

3D structure databases

ProteinModelPortali P67003.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 224914.BMEI2017.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAL53198 ; AAL53198 ; BMEI2017 .
GeneIDi 1197728.
KEGGi bme:BMEI2017.
PATRICi 17854486. VBIBruMel92729_2226.

Phylogenomic databases

HOGENOMi HOG000161598.
KOi K01817.
OMAi DILQLHG.
OrthoDBi EOG6N94DF.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .
BioCyci BMEL224914:GCJ0-2064-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 16M / ATCC 23456 / NCTC 10094.

Entry informationi

Entry nameiTRPF_BRUME
AccessioniPrimary (citable) accession number: P67003
Secondary accession number(s): Q8FXY3, Q8YE61
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: October 1, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella melitensis
    Brucella melitensis (strain 16M): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3