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P67003

- TRPF_BRUME

UniProt

P67003 - TRPF_BRUME

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Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene
trpF, BMEI2017
Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciBMEL224914:GCJ0-2064-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase (EC:5.3.1.24)
Short name:
PRAI
Gene namesi
Name:trpF
Ordered Locus Names:BMEI2017
OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Taxonomic identifieri224914 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000000419: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 222222N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotationPRO_0000154348Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi224914.BMEI2017.

Structurei

3D structure databases

ProteinModelPortaliP67003.

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.

Phylogenomic databases

HOGENOMiHOG000161598.
KOiK01817.
OMAiDILQLHG.
OrthoDBiEOG6N94DF.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

P67003-1 [UniParc]FASTAAdd to Basket

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MALDIKICGL KTPEAVAAAL DGGATHIGFI FFPKSPRHIT PDAAARLRAA    50
ATGRAVAVAV TVDADDEALD EIVKTVRPDM LQLHGGETPE RVRFLKERYN 100
LPVMKAFSIR EAGDLEAIAP YRGIADRFLF DAKPPKGSEL PGGNGISFDW 150
NLLAALDADI DYMLSGGLNA DNIAEALLKT GAPGIDISSG VECAPGEKDV 200
RLIENFFQAV ADANAQPFAR RA 222
Length:222
Mass (Da):23,614
Last modified:October 11, 2004 - v1
Checksum:i28E7AFA3258F5514
GO

Sequence cautioni

The sequence AAL53198.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE008917 Genomic DNA. Translation: AAL53198.1. Different initiation.
PIRiAC3504.
RefSeqiNP_540934.1. NC_003317.1.

Genome annotation databases

EnsemblBacteriaiAAL53198; AAL53198; BMEI2017.
GeneIDi1197728.
KEGGibme:BMEI2017.
PATRICi17854486. VBIBruMel92729_2226.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE008917 Genomic DNA. Translation: AAL53198.1 . Different initiation.
PIRi AC3504.
RefSeqi NP_540934.1. NC_003317.1.

3D structure databases

ProteinModelPortali P67003.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 224914.BMEI2017.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAL53198 ; AAL53198 ; BMEI2017 .
GeneIDi 1197728.
KEGGi bme:BMEI2017.
PATRICi 17854486. VBIBruMel92729_2226.

Phylogenomic databases

HOGENOMi HOG000161598.
KOi K01817.
OMAi DILQLHG.
OrthoDBi EOG6N94DF.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .
BioCyci BMEL224914:GCJ0-2064-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 16M / ATCC 23456 / NCTC 10094.

Entry informationi

Entry nameiTRPF_BRUME
AccessioniPrimary (citable) accession number: P67003
Secondary accession number(s): Q8FXY3, Q8YE61
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: May 14, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella melitensis
    Brucella melitensis (strain 16M): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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