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Protein

Probable transaldolase 2

Gene

tal2

Organism
Listeria innocua serovar 6a (strain CLIP 11262)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.UniRule annotation

Catalytic activityi

Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei83 – 831Schiff-base intermediate with substrateUniRule annotation

GO - Molecular functioni

  1. sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
  2. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Pentose shunt

Keywords - Ligandi

Schiff base

Enzyme and pathway databases

UniPathwayiUPA00115; UER00414.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable transaldolase 2UniRule annotation (EC:2.2.1.2UniRule annotation)
Gene namesi
Name:tal2UniRule annotation
Ordered Locus Names:lin0361
OrganismiListeria innocua serovar 6a (strain CLIP 11262)
Taxonomic identifieri272626 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria
ProteomesiUP000002513 Componenti: Chromosome

Organism-specific databases

GenoListiLIN0361.

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 218218Probable transaldolase 2PRO_0000173672Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272626.lin0361.

Structurei

3D structure databases

ProteinModelPortaliP66958.
SMRiP66958. Positions 1-214.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the transaldolase family. Type 3B subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0176.
HOGENOMiHOG000226073.
KOiK00616.
OMAiFTKDWET.
OrthoDBiEOG6PS600.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00494. Transaldolase_3b.
InterProiIPR013785. Aldolase_TIM.
IPR001585. Transaldolase.
IPR004731. Transaldolase_3A/3B.
IPR022999. Transaldolase_3B.
IPR018225. Transaldolase_AS.
[Graphical view]
PANTHERiPTHR10683. PTHR10683. 1 hit.
PfamiPF00923. Transaldolase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00875. fsa_talC_mipB. 1 hit.
PROSITEiPS01054. TRANSALDOLASE_1. 1 hit.
PS00958. TRANSALDOLASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P66958-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKFFLDTASV SEIKRISELG LVDGVTTNPT IIAKEGRPFE EVIKEICSIV
60 70 80 90 100
DGPVSAEVIG LEADKMVEEA RILAKWAPNV VVKIPMTEEG LKAVHTLTAE
110 120 130 140 150
GIKTNVTLIF TVSQGLMAAK AGATYISPFL GRLDDIGTDG MILIKNLKKV
160 170 180 190 200
LDNYGLKAEI ISASIRHIGH LEEAAEAGAH IATIPGSLFP KLWSHPLTDK
210
GIEGFLKDWE AFSQKEGN
Length:218
Mass (Da):23,551
Last modified:October 10, 2004 - v1
Checksum:iCFC83FA79509A312
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL596164 Genomic DNA. Translation: CAC95594.1.
PIRiAB1478.
RefSeqiNP_469706.1. NC_003212.1.

Genome annotation databases

KEGGilin:lin0361.
PATRICi20297404. VBILisInn102668_0376.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL596164 Genomic DNA. Translation: CAC95594.1.
PIRiAB1478.
RefSeqiNP_469706.1. NC_003212.1.

3D structure databases

ProteinModelPortaliP66958.
SMRiP66958. Positions 1-214.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272626.lin0361.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

KEGGilin:lin0361.
PATRICi20297404. VBILisInn102668_0376.

Organism-specific databases

GenoListiLIN0361.

Phylogenomic databases

eggNOGiCOG0176.
HOGENOMiHOG000226073.
KOiK00616.
OMAiFTKDWET.
OrthoDBiEOG6PS600.

Enzyme and pathway databases

UniPathwayiUPA00115; UER00414.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00494. Transaldolase_3b.
InterProiIPR013785. Aldolase_TIM.
IPR001585. Transaldolase.
IPR004731. Transaldolase_3A/3B.
IPR022999. Transaldolase_3B.
IPR018225. Transaldolase_AS.
[Graphical view]
PANTHERiPTHR10683. PTHR10683. 1 hit.
PfamiPF00923. Transaldolase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00875. fsa_talC_mipB. 1 hit.
PROSITEiPS01054. TRANSALDOLASE_1. 1 hit.
PS00958. TRANSALDOLASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CLIP 11262.

Entry informationi

Entry nameiTAL2_LISIN
AccessioniPrimary (citable) accession number: P66958
Secondary accession number(s): Q92EU7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 10, 2004
Last sequence update: October 10, 2004
Last modified: March 31, 2015
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.