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P66887 (TATA_BRUME) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Sec-independent protein translocase protein TatA
Gene names
Name:tatA
Ordered Locus Names:BMEI1084
OrganismBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) [Complete proteome] [HAMAP]
Taxonomic identifier224914 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length72 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system By similarity. HAMAP-Rule MF_00236

Subunit structure

The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon By similarity.

Subcellular location

Cell inner membrane; Single-pass membrane protein By similarity HAMAP-Rule MF_00236.

Sequence similarities

Belongs to the TatA/E family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 7272Sec-independent protein translocase protein TatA HAMAP-Rule MF_00236
PRO_0000097930

Regions

Transmembrane1 – 2121Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
P66887 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: 5F57A505041227AB

FASTA727,999
        10         20         30         40         50         60 
MGSFSIWHWL IVLAVVLLLF GRGKIPELMG DVAKGIKNFK QGMADEDAKE DPRTIDAKAE 

        70 
EPVKDVKKTT KS 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE008917 Genomic DNA. Translation: AAL52265.1.
PIRAF3387.
RefSeqNP_540001.1. NC_003317.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING224914.BMEI1084.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAL52265; AAL52265; BMEI1084.
GeneID1196795.
KEGGbme:BMEI1084.
PATRIC17797862. VBIBruMel146950_0747.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000245363.
KOK03116.
OMAELMGDMA.
OrthoDBEOG6WQD34.
ProtClustDBPRK00720.

Family and domain databases

HAMAPMF_00236. TatA_E.
InterProIPR003369. TatA/B/E.
IPR006312. TatA/E.
[Graphical view]
PfamPF02416. MttA_Hcf106. 1 hit.
[Graphical view]
TIGRFAMsTIGR01411. tatAE. 1 hit.
ProtoNetSearch...

Entry information

Entry nameTATA_BRUME
AccessionPrimary (citable) accession number: P66887
Secondary accession number(s): Q8G142, Q8YGS4
Entry history
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: February 19, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Brucella melitensis

Brucella melitensis (strain 16M): entries and gene names