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P66887

- TATA_BRUME

UniProt

P66887 - TATA_BRUME

Protein

Sec-independent protein translocase protein TatA

Gene

tatA

Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
  1. Functioni

    Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.UniRule annotation

    GO - Molecular functioni

    1. protein transmembrane transporter activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. protein secretion Source: InterPro
    2. protein transport by the Tat complex Source: UniProtKB-HAMAP

    Keywords - Biological processi

    Protein transport, Translocation, Transport

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Sec-independent protein translocase protein TatAUniRule annotation
    Gene namesi
    Name:tatAUniRule annotation
    Ordered Locus Names:BMEI1084
    OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
    Taxonomic identifieri224914 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000000419: Chromosome I

    Subcellular locationi

    Cell inner membrane UniRule annotation; Single-pass membrane protein UniRule annotation

    GO - Cellular componenti

    1. integral component of plasma membrane Source: UniProtKB-HAMAP
    2. TAT protein transport complex Source: UniProtKB-HAMAP

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 7272Sec-independent protein translocase protein TatAPRO_0000097930Add
    BLAST

    Interactioni

    Subunit structurei

    The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.UniRule annotation

    Protein-protein interaction databases

    STRINGi224914.BMEI1084.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei1 – 2121HelicalUniRule annotationAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the TatA/E family.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    HOGENOMiHOG000245363.
    KOiK03116.
    OMAiCTMSHEL.
    OrthoDBiEOG6WQD34.

    Family and domain databases

    HAMAPiMF_00236. TatA_E.
    InterProiIPR003369. TatA/B/E.
    IPR006312. TatA/E.
    [Graphical view]
    PfamiPF02416. MttA_Hcf106. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR01411. tatAE. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P66887-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGSFSIWHWL IVLAVVLLLF GRGKIPELMG DVAKGIKNFK QGMADEDAKE   50
    DPRTIDAKAE EPVKDVKKTT KS 72
    Length:72
    Mass (Da):7,999
    Last modified:October 11, 2004 - v1
    Checksum:i5F57A505041227AB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE008917 Genomic DNA. Translation: AAL52265.1.
    PIRiAF3387.
    RefSeqiNP_540001.1. NC_003317.1.

    Genome annotation databases

    EnsemblBacteriaiAAL52265; AAL52265; BMEI1084.
    GeneIDi1196795.
    KEGGibme:BMEI1084.
    PATRICi17797862. VBIBruMel146950_0747.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE008917 Genomic DNA. Translation: AAL52265.1 .
    PIRi AF3387.
    RefSeqi NP_540001.1. NC_003317.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 224914.BMEI1084.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAL52265 ; AAL52265 ; BMEI1084 .
    GeneIDi 1196795.
    KEGGi bme:BMEI1084.
    PATRICi 17797862. VBIBruMel146950_0747.

    Phylogenomic databases

    HOGENOMi HOG000245363.
    KOi K03116.
    OMAi CTMSHEL.
    OrthoDBi EOG6WQD34.

    Family and domain databases

    HAMAPi MF_00236. TatA_E.
    InterProi IPR003369. TatA/B/E.
    IPR006312. TatA/E.
    [Graphical view ]
    Pfami PF02416. MttA_Hcf106. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR01411. tatAE. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 16M / ATCC 23456 / NCTC 10094.

    Entry informationi

    Entry nameiTATA_BRUME
    AccessioniPrimary (citable) accession number: P66887
    Secondary accession number(s): Q8G142, Q8YGS4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 11, 2004
    Last sequence update: October 11, 2004
    Last modified: October 1, 2014
    This is version 54 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Brucella melitensis
      Brucella melitensis (strain 16M): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3