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Protein

Sec-independent protein translocase protein TatA

Gene

tatA

Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, Translocation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Sec-independent protein translocase protein TatAUniRule annotation
Gene namesi
Name:tatAUniRule annotation
Ordered Locus Names:BMEI1084
OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Taxonomic identifieri224914 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000000419 Componenti: Chromosome I

Subcellular locationi

  • Cell inner membrane UniRule annotation; Single-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei1 – 2121HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 7272Sec-independent protein translocase protein TatAPRO_0000097930Add
BLAST

Interactioni

Subunit structurei

The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.UniRule annotation

Protein-protein interaction databases

STRINGi224914.BAWG_1124.

Family & Domainsi

Sequence similaritiesi

Belongs to the TatA/E family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000245363.
KOiK03116.
OMAiELMGDMA.
OrthoDBiEOG6WQD34.

Family and domain databases

HAMAPiMF_00236. TatA_E.
InterProiIPR003369. TatA/B/E.
IPR006312. TatA/E.
[Graphical view]
PfamiPF02416. MttA_Hcf106. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01411. tatAE. 1 hit.

Sequencei

Sequence statusi: Complete.

P66887-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSFSIWHWL IVLAVVLLLF GRGKIPELMG DVAKGIKNFK QGMADEDAKE
60 70
DPRTIDAKAE EPVKDVKKTT KS
Length:72
Mass (Da):7,999
Last modified:October 11, 2004 - v1
Checksum:i5F57A505041227AB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008917 Genomic DNA. Translation: AAL52265.1.
PIRiAF3387.
RefSeqiWP_002964012.1. NZ_GG703778.1.

Genome annotation databases

EnsemblBacteriaiAAL52265; AAL52265; BMEI1084.
GeneIDi3787576.
KEGGibme:BMEI1084.
PATRICi17797862. VBIBruMel146950_0747.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008917 Genomic DNA. Translation: AAL52265.1.
PIRiAF3387.
RefSeqiWP_002964012.1. NZ_GG703778.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224914.BAWG_1124.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL52265; AAL52265; BMEI1084.
GeneIDi3787576.
KEGGibme:BMEI1084.
PATRICi17797862. VBIBruMel146950_0747.

Phylogenomic databases

HOGENOMiHOG000245363.
KOiK03116.
OMAiELMGDMA.
OrthoDBiEOG6WQD34.

Family and domain databases

HAMAPiMF_00236. TatA_E.
InterProiIPR003369. TatA/B/E.
IPR006312. TatA/E.
[Graphical view]
PfamiPF02416. MttA_Hcf106. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01411. tatAE. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 16M / ATCC 23456 / NCTC 10094.

Entry informationi

Entry nameiTATA_BRUME
AccessioniPrimary (citable) accession number: P66887
Secondary accession number(s): Q8G142, Q8YGS4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: July 22, 2015
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella melitensis
    Brucella melitensis (strain 16M): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.