P66858 (SSRP_BRUME) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
SsrA-binding protein

Gene names

Name:	smpB
Ordered Locus Names:	BMEI1300

Organism

Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) [Complete proteome] [HAMAP]

Taxonomic identifier

224914 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella melitensis › Brucella melitensis bv. 1

Protein attributes

Sequence length	158 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes By similarity. HAMAP-Rule MF_00023
Subcellular location	Cytoplasm Potential HAMAP-Rule MF_00023.
Sequence similarities	Belongs to the SmpB family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	RNA-binding
Technical term	Complete proteome
Gene Ontology (GO)
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	RNA binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 158	158	SsrA-binding protein HAMAP-Rule MF_00023		PRO_0000102918

Sequences

	Sequence		Length	Mass (Da)
	P66858 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: F034DAD1DDD08D6E	FASTA	158	18,570
	10 20 30 40 50 60 MNKPKNSPAR KMIAENRKAR FNFEILDTLE AGLVLTGTEV KSLRANQANI AESYASFEDG 70 80 90 100 110 120 EFWLINSYIP EYTQGNRFNH EPRRLRKLLV SRREMSRLFN SVSREGMTVV PLKLYFNDRG 130 140 150 RAKLELALAR GKKTHDKRET EKKRDWNREK ARLLRDRG

References

[1]

"The genome sequence of the facultative intracellular pathogen Brucella melitensis." DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T., Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G., Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E., Selkov E. , Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J., Haselkorn R., Kyrpides N.C., Overbeek R. Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 16M / ATCC 23456 / NCTC 10094.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE008917 Genomic DNA. Translation: AAL52481.1.
PIR	AF3414.
RefSeq	NP_540217.1. NC_003317.1.
3D structure databases
ProteinModelPortal	P66858.
SMR	P66858. Positions 11-132.
ModBase	Search...
Protein-protein interaction databases
STRING	224914.BMEI1300.
Proteomic databases
PRIDE	P66858.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAL52481; AAL52481; BMEI1300.
GeneID	1197011.
KEGG	bme:BMEI1300.
PATRIC	17797365. VBIBruMel146950_0501.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000009628.
KO	K03664.
OMA	EEKYEAG.
ProtClustDB	PRK05422.
Family and domain databases
Gene3D	2.40.280.10. 1 hit.
HAMAP	MF_00023. SmpB.
InterPro	IPR023620. SmpB. IPR000037. SsrA-bd_prot. IPR020081. SsrA-bd_prot_CS. [Graphical view]
Pfam	PF01668. SmpB. 1 hit. [Graphical view]
ProDom	PD004488. SmpB. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF74982. SmpB. 1 hit.
TIGRFAMs	TIGR00086. smpB. 1 hit.
PROSITE	PS01317. SSRP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SSRP_BRUME

Accession

Primary (citable) accession number: P66858
Secondary accession number(s): Q8YG61

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 11, 2004
Last sequence update:	October 11, 2004
Last modified:	May 1, 2013
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program