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Protein

Anti-sigma-B factor antagonist

Gene

rsbV

Organism
Staphylococcus aureus (strain MW2)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Positive regulator of sigma-B activity. Non-phosphorylated RsbV binds to RsbW, preventing its association with sigma-B. When phosphorylated, releases RsbW, which is then free to complex with and inactivate sigma-B (By similarity).By similarity

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Anti-sigma-B factor antagonist
Alternative name(s):
Anti-anti-sigma-B factor
Gene namesi
Name:rsbV
Ordered Locus Names:MW1990
OrganismiStaphylococcus aureus (strain MW2)
Taxonomic identifieri196620 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000000418 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001941931 – 108Anti-sigma-B factor antagonistAdd BLAST108

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei57PhosphoserineBy similarity1

Post-translational modificationi

Phosphorylated by RsbW on a serine residue.By similarity

Keywords - PTMi

Phosphoprotein

Structurei

3D structure databases

ProteinModelPortaliP66839.
SMRiP66839.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 108STASPROSITE-ProRule annotationAdd BLAST106

Sequence similaritiesi

Contains 1 STAS domain.PROSITE-ProRule annotation

Phylogenomic databases

HOGENOMiHOG000270156.
KOiK04749.
OMAiHLLVNME.

Family and domain databases

Gene3Di3.30.750.24. 1 hit.
InterProiIPR003658. Anti-sigma_ant.
IPR002645. STAS_dom.
[Graphical view]
PfamiPF01740. STAS. 1 hit.
[Graphical view]
SUPFAMiSSF52091. SSF52091. 1 hit.
TIGRFAMsiTIGR00377. ant_ant_sig. 1 hit.
PROSITEiPS50801. STAS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P66839-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLNIETTTQ DKFYEVKVGG ELDVYTVPEL EEVLTPMRQD GTRDIYVNLE
60 70 80 90 100
NVSYMDSTGL GLFVGTLKAL NQNDKELYIL GVSDRIGRLF EITGLKDLMH

VNEGTEVE
Length:108
Mass (Da):12,205
Last modified:October 11, 2004 - v1
Checksum:i461FC096E18D9AEE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000033 Genomic DNA. Translation: BAB95855.1.
RefSeqiWP_001052491.1. NC_003923.1.

Genome annotation databases

EnsemblBacteriaiBAB95855; BAB95855; BAB95855.
GeneIDi28380352.
KEGGisam:MW1990.
PATRICi19570696. VBIStaAur44266_2066.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000033 Genomic DNA. Translation: BAB95855.1.
RefSeqiWP_001052491.1. NC_003923.1.

3D structure databases

ProteinModelPortaliP66839.
SMRiP66839.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAB95855; BAB95855; BAB95855.
GeneIDi28380352.
KEGGisam:MW1990.
PATRICi19570696. VBIStaAur44266_2066.

Phylogenomic databases

HOGENOMiHOG000270156.
KOiK04749.
OMAiHLLVNME.

Family and domain databases

Gene3Di3.30.750.24. 1 hit.
InterProiIPR003658. Anti-sigma_ant.
IPR002645. STAS_dom.
[Graphical view]
PfamiPF01740. STAS. 1 hit.
[Graphical view]
SUPFAMiSSF52091. SSF52091. 1 hit.
TIGRFAMsiTIGR00377. ant_ant_sig. 1 hit.
PROSITEiPS50801. STAS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRSBV_STAAW
AccessioniPrimary (citable) accession number: P66839
Secondary accession number(s): Q925Z9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: November 2, 2016
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.