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Protein

Anti-sigma-B factor antagonist

Gene

rsbV

Organism
Staphylococcus aureus (strain Mu50 / ATCC 700699)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Positive regulator of sigma-B activity. Non-phosphorylated RsbV binds to RsbW, preventing its association with sigma-B. When phosphorylated, releases RsbW, which is then free to complex with and inactivate sigma-B (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Anti-sigma-B factor antagonist
Alternative name(s):
Anti-anti-sigma-B factor
Gene namesi
Name:rsbV
Ordered Locus Names:SAV2066
OrganismiStaphylococcus aureus (strain Mu50 / ATCC 700699)
Taxonomic identifieri158878 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000002481 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001941891 – 108Anti-sigma-B factor antagonistAdd BLAST108

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei57PhosphoserineBy similarity1

Post-translational modificationi

Phosphorylated by RsbW on a serine residue.By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP66837

2D gel databases

World-2DPAGEi0002:P66837

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi158878.SAV2066

Structurei

3D structure databases

ProteinModelPortaliP66837
SMRiP66837
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 108STASPROSITE-ProRule annotationAdd BLAST106

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105WN5 Bacteria
COG1366 LUCA
KOiK04749
OMAiVYTAPKL
PhylomeDBiP66837

Family and domain databases

Gene3Di3.30.750.24, 1 hit
InterProiView protein in InterPro
IPR003658 Anti-sigma_ant
IPR002645 STAS_dom
IPR036513 STAS_dom_sf
PfamiView protein in Pfam
PF01740 STAS, 1 hit
SUPFAMiSSF52091 SSF52091, 1 hit
TIGRFAMsiTIGR00377 ant_ant_sig, 1 hit
PROSITEiView protein in PROSITE
PS50801 STAS, 1 hit

Sequencei

Sequence statusi: Complete.

P66837-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLNIETTTQ DKFYEVKVGG ELDVYTVPEL EEVLTPMRQD GTRDIYVNLE
60 70 80 90 100
NVSYMDSTGL GLFVGTLKAL NQNDKELYIL GVSDRIGRLF EITGLKDLMH

VNEGTEVE
Length:108
Mass (Da):12,205
Last modified:October 11, 2004 - v1
Checksum:i461FC096E18D9AEE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000017 Genomic DNA Translation: BAB58228.1
RefSeqiWP_001052491.1, NC_002758.2

Genome annotation databases

EnsemblBacteriaiBAB58228; BAB58228; SAV2066
KEGGisav:SAV2066

Similar proteinsi

Entry informationi

Entry nameiRSBV_STAAM
AccessioniPrimary (citable) accession number: P66837
Secondary accession number(s): Q925Z9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: March 28, 2018
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health