P66696 (RPIA_STAAW) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribose-5-phosphate isomerase A
EC=5.3.1.6

Alternative name(s):
Phosphoriboisomerase A
Short name=PRI

Gene names

Name:	rpiA
Ordered Locus Names:	MW2256

Organism

Staphylococcus aureus (strain MW2) [Complete proteome] [HAMAP]

Taxonomic identifier

196620 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	228 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-ribose 5-phosphate = D-ribulose 5-phosphate. HAMAP MF_00170
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1. HAMAP MF_00170
Sequence similarities	Belongs to the ribose 5-phosphate isomerase family.

Ontologies

Keywords
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt, non-oxidative branch Inferred from electronic annotation. Source: InterPro
Molecular function	ribose-5-phosphate isomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 228	228	Ribose-5-phosphate isomerase A HAMAP MF_00170		PRO_0000158468

Sequences

	Sequence		Length	Mass (Da)
	P66696 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: AF9BFF0C9394537A	FASTA	228	25,550
	10 20 30 40 50 60 MKDVKALKLM TLNDVLSQIN GDMTLGIGTG STMELLLPQM AQLIKERGYN ITGVCTSNKI 70 80 90 100 110 120 AFLAKELGIK ICEINDVDHI DLAIDGADEV DPSLNIIKGG GGALFREKVI DEMASRFVVV 130 140 150 160 170 180 VDETKIVQYL GETFKLPVEV DKFNWYHILR KIESYADIKV ERRVNEDVAF ITDNGNYILD 190 200 210 220 CKLPKGIDPY KFHEYLIHLT GVFETGYFLD MADQVIVGTQ EGVKILEK

References

[1]	"Genome and virulence determinants of high virulence community-acquired MRSA." Baba T., Takeuchi F., Kuroda M., Yuzawa H., Aoki K., Oguchi A., Nagai Y., Iwama N., Asano K., Naimi T., Kuroda H., Cui L., Yamamoto K., Hiramatsu K. Lancet 359:1819-1827(2002) [PubMed: 12044378] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MW2.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000033 Genomic DNA. Translation: BAB96121.1.
RefSeq	NP_647073.1. NC_003923.1.
3D structure databases
ProteinModelPortal	P66696.
ModBase	Search...
Protein-protein interaction databases
STRING	P66696.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTAT00000025322; EBSTAP00000024361; EBSTAG00000025321.
GeneID	1004374.
GenomeReviews	Gene locus MW2256 in contig BA000033_GR.
KEGG	sam:MW2256.
PATRIC	19571244. VBIStaAur44266_2332.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0120.
GeneTree	EBGT00050000025309.
HOGENOM	HBG515603.
OMA	NLSLYVD.
PhylomeDB	P66696.
ProtClustDB	PRK13978.
Enzyme and pathway databases
BioCyc	SAUR196620:MW2256-MONOMER.
Family and domain databases
HAMAP	MF_00170. Rib_5P_isom_A. [Tree]
InterPro	IPR004788. Ribose5P_isomerase_typA. IPR020672. Ribose5P_isomerase_typA_subgr. [Graphical view]
KO	K01807.
PANTHER	PTHR11934. RpiA. 1 hit.
Pfam	PF06026. Rib_5-P_isom_A. 1 hit. [Graphical view]
TIGRFAMs	TIGR00021. RpiA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RPIA_STAAW

Accession

Primary (citable) accession number: P66696
Secondary accession number(s): Q99RT7

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 11, 2004
Last sequence update:	October 11, 2004
Last modified:	January 25, 2012
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program