P66619 (RS7_STRP1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
30S ribosomal protein S7

Gene names

Name:	rpsG
Ordered Locus Names:	SPy_0272, M5005_Spy0231

Organism

Streptococcus pyogenes serotype M1 [Complete proteome] [HAMAP]

Taxonomic identifier

301447 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Streptococcaceae › Streptococcus › Streptococcus pyogenes

Protein attributes

Sequence length	156 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA By similarity. HAMAP-Rule MF_00480
Subunit structure	Part of the 30S ribosomal subunit. Contacts proteins S9 and S11 By similarity.
Sequence similarities	Belongs to the ribosomal protein S7P family.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding tRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	translation Inferred from electronic annotation. Source: HAMAP
Cellular_component	small ribosomal subunit Inferred from electronic annotation. Source: InterPro
Molecular_function	rRNA binding Inferred from electronic annotation. Source: HAMAP structural constituent of ribosome Inferred from electronic annotation. Source: InterPro tRNA binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 156	156	30S ribosomal protein S7 HAMAP-Rule MF_00480		PRO_0000124357
Experimental info
	Sequence conflict	72	1	V → A in AAZ50850. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	P66619 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: 9790B8921284F3EC	FASTA	156	17,679
	10 20 30 40 50 60 MSRKNQAPKR EVLPDPLYNS KIVTRLINRV MLDGKRGTAA TIVYDAFNAI KEATGNDALE 70 80 90 100 110 120 VFETAMDNIM PVLEVRARRV GGSNYQVPVE VRPERRTTLG LRWLVNASRA RGEHTMKDRL 130 140 150 AKEIMDAANN TGASVKKRED THKMAEANRA FAHFRW

References

[1]

"Complete genome sequence of an M1 strain of Streptococcus pyogenes." Ferretti J.J., McShan W.M., Ajdic D.J., Savic D.J., Savic G., Lyon K., Primeaux C., Sezate S., Suvorov A.N., Kenton S., Lai H.S., Lin S.P., Qian Y., Jia H.G., Najar F.Z., Ren Q., Zhu H., Song L. , White J., Yuan X., Clifton S.W., Roe B.A., McLaughlin R.E. Proc. Natl. Acad. Sci. U.S.A. 98:4658-4663(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700294 / SF370 / Serotype M1.

[2]

"Evolutionary origin and emergence of a highly successful clone of serotype M1 group A Streptococcus involved multiple horizontal gene transfer events." Sumby P., Porcella S.F., Madrigal A.G., Barbian K.D., Virtaneva K., Ricklefs S.M., Sturdevant D.E., Graham M.R., Vuopio-Varkila J., Hoe N.P., Musser J.M. J. Infect. Dis. 192:771-782(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-947 / MGAS5005 / Serotype M1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE004092 Genomic DNA. Translation: AAK33346.1. CP000017 Genomic DNA. Translation: AAZ50850.1.
RefSeq	NP_268625.1. NC_002737.1. YP_281595.1. NC_007297.1.
3D structure databases
ProteinModelPortal	P66619.
SMR	P66619. Positions 10-148.
ModBase	Search...
Protein-protein interaction databases
STRING	160490.SPy_0272.
Proteomic databases
PaxDb	P66619.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAK33346; AAK33346; SPy_0272. AAZ50850; AAZ50850; M5005_Spy0231.
GeneID	3572698. 900571.
KEGG	spy:SPy_0272. spz:M5005_Spy_0231.
PATRIC	19714329. VBIStrPyo79812_0239.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0049.
HOGENOM	HOG000039067.
KO	K02992.
OMA	RREKTMT.
ProtClustDB	PRK05302.
Family and domain databases
Gene3D	1.10.455.10. 1 hit.
HAMAP	MF_00480_B. Ribosomal_S7_B.
InterPro	IPR000235. Ribosomal_S5/S7. IPR005717. Ribosomal_S7_bac/org-type. IPR020606. Ribosomal_S7_CS. IPR023798. Ribosomal_S7_dom. [Graphical view]
PANTHER	PTHR11205. PTHR11205. 1 hit. PTHR11205:SF13. PTHR11205:SF13. 1 hit.
Pfam	PF00177. Ribosomal_S7. 1 hit. [Graphical view]
PIRSF	PIRSF002122. RPS7p_RPS7a_RPS5e_RPS7o. 1 hit.
SUPFAM	SSF47973. Ribosomal_S7. 1 hit.
TIGRFAMs	TIGR01029. rpsG_bact. 1 hit.
PROSITE	PS00052. RIBOSOMAL_S7. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RS7_STRP1

Accession

Primary (citable) accession number: P66619
Secondary accession number(s): Q490W8, Q9A1H2

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 11, 2004
Last sequence update:	October 11, 2004
Last modified:	May 1, 2013
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program