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P66619

- RS7_STRP1

UniProt

P66619 - RS7_STRP1

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Protein
30S ribosomal protein S7
Gene
rpsG, SPy_0272, M5005_Spy0231
Organism
Streptococcus pyogenes serotype M1
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA By similarity.UniRule annotation

GO - Molecular functioni

  1. rRNA binding Source: UniProtKB-HAMAP
  2. structural constituent of ribosome Source: InterPro
  3. tRNA binding Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. translation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding, tRNA-binding

Enzyme and pathway databases

BioCyciSPYO160490:GJ81-249-MONOMER.
SPYO293653:GHFC-281-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
30S ribosomal protein S7
Gene namesi
Name:rpsG
Ordered Locus Names:SPy_0272, M5005_Spy0231
OrganismiStreptococcus pyogenes serotype M1
Taxonomic identifieri301447 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000000750: Chromosome, UP000002702: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. small ribosomal subunit Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 15615630S ribosomal protein S7UniRule annotation
PRO_0000124357Add
BLAST

Proteomic databases

PaxDbiP66619.

Interactioni

Subunit structurei

Part of the 30S ribosomal subunit. Contacts proteins S9 and S11 By similarity.

Protein-protein interaction databases

STRINGi160490.SPy_0272.

Structurei

3D structure databases

ProteinModelPortaliP66619.
SMRiP66619. Positions 10-148.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0049.
HOGENOMiHOG000039067.
KOiK02992.
OMAiWIVNYAR.
OrthoDBiEOG6P5ZKW.

Family and domain databases

Gene3Di1.10.455.10. 1 hit.
HAMAPiMF_00480_B. Ribosomal_S7_B.
InterProiIPR000235. Ribosomal_S5/S7.
IPR005717. Ribosomal_S7_bac/org-type.
IPR020606. Ribosomal_S7_CS.
IPR023798. Ribosomal_S7_dom.
[Graphical view]
PANTHERiPTHR11205. PTHR11205. 1 hit.
PfamiPF00177. Ribosomal_S7. 1 hit.
[Graphical view]
PIRSFiPIRSF002122. RPS7p_RPS7a_RPS5e_RPS7o. 1 hit.
SUPFAMiSSF47973. SSF47973. 1 hit.
TIGRFAMsiTIGR01029. rpsG_bact. 1 hit.
PROSITEiPS00052. RIBOSOMAL_S7. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P66619-1 [UniParc]FASTAAdd to Basket

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MSRKNQAPKR EVLPDPLYNS KIVTRLINRV MLDGKRGTAA TIVYDAFNAI    50
KEATGNDALE VFETAMDNIM PVLEVRARRV GGSNYQVPVE VRPERRTTLG 100
LRWLVNASRA RGEHTMKDRL AKEIMDAANN TGASVKKRED THKMAEANRA 150
FAHFRW 156
Length:156
Mass (Da):17,679
Last modified:October 11, 2004 - v1
Checksum:i9790B8921284F3EC
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti72 – 721V → A in AAZ50850. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE004092 Genomic DNA. Translation: AAK33346.1.
CP000017 Genomic DNA. Translation: AAZ50850.1.
RefSeqiNP_268625.1. NC_002737.1.
YP_281595.1. NC_007297.1.

Genome annotation databases

EnsemblBacteriaiAAK33346; AAK33346; SPy_0272.
AAZ50850; AAZ50850; M5005_Spy0231.
GeneIDi3572698.
900571.
KEGGispy:SPy_0272.
spz:M5005_Spy_0231.
PATRICi19714329. VBIStrPyo79812_0239.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE004092 Genomic DNA. Translation: AAK33346.1 .
CP000017 Genomic DNA. Translation: AAZ50850.1 .
RefSeqi NP_268625.1. NC_002737.1.
YP_281595.1. NC_007297.1.

3D structure databases

ProteinModelPortali P66619.
SMRi P66619. Positions 10-148.
ModBasei Search...

Protein-protein interaction databases

STRINGi 160490.SPy_0272.

Chemistry

ChEMBLi CHEMBL2364103.

Proteomic databases

PaxDbi P66619.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAK33346 ; AAK33346 ; SPy_0272 .
AAZ50850 ; AAZ50850 ; M5005_Spy0231 .
GeneIDi 3572698.
900571.
KEGGi spy:SPy_0272.
spz:M5005_Spy_0231.
PATRICi 19714329. VBIStrPyo79812_0239.

Phylogenomic databases

eggNOGi COG0049.
HOGENOMi HOG000039067.
KOi K02992.
OMAi WIVNYAR.
OrthoDBi EOG6P5ZKW.

Enzyme and pathway databases

BioCyci SPYO160490:GJ81-249-MONOMER.
SPYO293653:GHFC-281-MONOMER.

Family and domain databases

Gene3Di 1.10.455.10. 1 hit.
HAMAPi MF_00480_B. Ribosomal_S7_B.
InterProi IPR000235. Ribosomal_S5/S7.
IPR005717. Ribosomal_S7_bac/org-type.
IPR020606. Ribosomal_S7_CS.
IPR023798. Ribosomal_S7_dom.
[Graphical view ]
PANTHERi PTHR11205. PTHR11205. 1 hit.
Pfami PF00177. Ribosomal_S7. 1 hit.
[Graphical view ]
PIRSFi PIRSF002122. RPS7p_RPS7a_RPS5e_RPS7o. 1 hit.
SUPFAMi SSF47973. SSF47973. 1 hit.
TIGRFAMsi TIGR01029. rpsG_bact. 1 hit.
PROSITEi PS00052. RIBOSOMAL_S7. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700294 / SF370 / Serotype M1.
  2. "Evolutionary origin and emergence of a highly successful clone of serotype M1 group A Streptococcus involved multiple horizontal gene transfer events."
    Sumby P., Porcella S.F., Madrigal A.G., Barbian K.D., Virtaneva K., Ricklefs S.M., Sturdevant D.E., Graham M.R., Vuopio-Varkila J., Hoe N.P., Musser J.M.
    J. Infect. Dis. 192:771-782(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-947 / MGAS5005 / Serotype M1.

Entry informationi

Entry nameiRS7_STRP1
AccessioniPrimary (citable) accession number: P66619
Secondary accession number(s): Q490W8, Q9A1H2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: June 11, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi