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Protein

30S ribosomal protein S7

Gene

rpsG

Organism
Streptococcus pyogenes serotype M1
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding, tRNA-binding

Enzyme and pathway databases

BioCyciSPYO160490:GJ81-249-MONOMER.
SPYO293653:GHFC-281-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
30S ribosomal protein S7UniRule annotation
Gene namesi
Name:rpsGUniRule annotation
Ordered Locus Names:SPy_0272, M5005_Spy0231
OrganismiStreptococcus pyogenes serotype M1
Taxonomic identifieri301447 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000000750 Componenti: Chromosome UP000002702 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 15615630S ribosomal protein S7PRO_0000124357Add
BLAST

Proteomic databases

PaxDbiP66619.

Interactioni

Subunit structurei

Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.UniRule annotation

Protein-protein interaction databases

STRINGi160490.SPy_0272.

Structurei

3D structure databases

ProteinModelPortaliP66619.
SMRiP66619. Positions 10-148.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein S7P family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0049.
HOGENOMiHOG000039067.
KOiK02992.
OMAiEVHRMAD.
OrthoDBiEOG6P5ZKW.

Family and domain databases

Gene3Di1.10.455.10. 1 hit.
HAMAPiMF_00480_B. Ribosomal_S7_B.
InterProiIPR000235. Ribosomal_S5/S7.
IPR005717. Ribosomal_S7_bac/org-type.
IPR020606. Ribosomal_S7_CS.
IPR023798. Ribosomal_S7_dom.
[Graphical view]
PANTHERiPTHR11205. PTHR11205. 1 hit.
PfamiPF00177. Ribosomal_S7. 1 hit.
[Graphical view]
PIRSFiPIRSF002122. RPS7p_RPS7a_RPS5e_RPS7o. 1 hit.
SUPFAMiSSF47973. SSF47973. 1 hit.
TIGRFAMsiTIGR01029. rpsG_bact. 1 hit.
PROSITEiPS00052. RIBOSOMAL_S7. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P66619-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRKNQAPKR EVLPDPLYNS KIVTRLINRV MLDGKRGTAA TIVYDAFNAI
60 70 80 90 100
KEATGNDALE VFETAMDNIM PVLEVRARRV GGSNYQVPVE VRPERRTTLG
110 120 130 140 150
LRWLVNASRA RGEHTMKDRL AKEIMDAANN TGASVKKRED THKMAEANRA

FAHFRW
Length:156
Mass (Da):17,679
Last modified:October 11, 2004 - v1
Checksum:i9790B8921284F3EC
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti72 – 721V → A in AAZ50850 (PubMed:16088826).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004092 Genomic DNA. Translation: AAK33346.1.
CP000017 Genomic DNA. Translation: AAZ50850.1.
RefSeqiNP_268625.1. NC_002737.1.

Genome annotation databases

EnsemblBacteriaiAAK33346; AAK33346; SPy_0272.
AAZ50850; AAZ50850; M5005_Spy0231.
GeneIDi900571.
KEGGispy:SPy_0272.
spz:M5005_Spy_0231.
PATRICi19714329. VBIStrPyo79812_0239.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004092 Genomic DNA. Translation: AAK33346.1.
CP000017 Genomic DNA. Translation: AAZ50850.1.
RefSeqiNP_268625.1. NC_002737.1.

3D structure databases

ProteinModelPortaliP66619.
SMRiP66619. Positions 10-148.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi160490.SPy_0272.

Chemistry

ChEMBLiCHEMBL2364103.

Proteomic databases

PaxDbiP66619.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAK33346; AAK33346; SPy_0272.
AAZ50850; AAZ50850; M5005_Spy0231.
GeneIDi900571.
KEGGispy:SPy_0272.
spz:M5005_Spy_0231.
PATRICi19714329. VBIStrPyo79812_0239.

Phylogenomic databases

eggNOGiCOG0049.
HOGENOMiHOG000039067.
KOiK02992.
OMAiEVHRMAD.
OrthoDBiEOG6P5ZKW.

Enzyme and pathway databases

BioCyciSPYO160490:GJ81-249-MONOMER.
SPYO293653:GHFC-281-MONOMER.

Miscellaneous databases

PROiP66619.

Family and domain databases

Gene3Di1.10.455.10. 1 hit.
HAMAPiMF_00480_B. Ribosomal_S7_B.
InterProiIPR000235. Ribosomal_S5/S7.
IPR005717. Ribosomal_S7_bac/org-type.
IPR020606. Ribosomal_S7_CS.
IPR023798. Ribosomal_S7_dom.
[Graphical view]
PANTHERiPTHR11205. PTHR11205. 1 hit.
PfamiPF00177. Ribosomal_S7. 1 hit.
[Graphical view]
PIRSFiPIRSF002122. RPS7p_RPS7a_RPS5e_RPS7o. 1 hit.
SUPFAMiSSF47973. SSF47973. 1 hit.
TIGRFAMsiTIGR01029. rpsG_bact. 1 hit.
PROSITEiPS00052. RIBOSOMAL_S7. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700294 / SF370 / Serotype M1.
  2. "Evolutionary origin and emergence of a highly successful clone of serotype M1 group A Streptococcus involved multiple horizontal gene transfer events."
    Sumby P., Porcella S.F., Madrigal A.G., Barbian K.D., Virtaneva K., Ricklefs S.M., Sturdevant D.E., Graham M.R., Vuopio-Varkila J., Hoe N.P., Musser J.M.
    J. Infect. Dis. 192:771-782(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-947 / MGAS5005 / Serotype M1.

Entry informationi

Entry nameiRS7_STRP1
AccessioniPrimary (citable) accession number: P66619
Secondary accession number(s): Q490W8, Q9A1H2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: May 27, 2015
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.