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P66619 (RS7_STRP1) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
30S ribosomal protein S7
Gene names
Name:rpsG
Ordered Locus Names:SPy_0272, M5005_Spy0231
OrganismStreptococcus pyogenes serotype M1 [Complete proteome] [HAMAP]
Taxonomic identifier301447 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus

Protein attributes

Sequence length156 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA By similarity. HAMAP-Rule MF_00480

Subunit structure

Part of the 30S ribosomal subunit. Contacts proteins S9 and S11 By similarity.

Sequence similarities

Belongs to the ribosomal protein S7P family.

Ontologies

Keywords
   LigandRNA-binding
rRNA-binding
tRNA-binding
   Molecular functionRibonucleoprotein
Ribosomal protein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtranslation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentsmall ribosomal subunit

Inferred from electronic annotation. Source: InterPro

   Molecular_functionrRNA binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

structural constituent of ribosome

Inferred from electronic annotation. Source: InterPro

tRNA binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 15615630S ribosomal protein S7 HAMAP-Rule MF_00480
PRO_0000124357

Experimental info

Sequence conflict721V → A in AAZ50850. Ref.2

Sequences

Sequence LengthMass (Da)Tools
P66619 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: 9790B8921284F3EC

FASTA15617,679
        10         20         30         40         50         60 
MSRKNQAPKR EVLPDPLYNS KIVTRLINRV MLDGKRGTAA TIVYDAFNAI KEATGNDALE 

        70         80         90        100        110        120 
VFETAMDNIM PVLEVRARRV GGSNYQVPVE VRPERRTTLG LRWLVNASRA RGEHTMKDRL 

       130        140        150 
AKEIMDAANN TGASVKKRED THKMAEANRA FAHFRW 

« Hide

References

[1]"Complete genome sequence of an M1 strain of Streptococcus pyogenes."
Ferretti J.J., McShan W.M., Ajdic D.J., Savic D.J., Savic G., Lyon K., Primeaux C., Sezate S., Suvorov A.N., Kenton S., Lai H.S., Lin S.P., Qian Y., Jia H.G., Najar F.Z., Ren Q., Zhu H., Song L. expand/collapse author list , White J., Yuan X., Clifton S.W., Roe B.A., McLaughlin R.E.
Proc. Natl. Acad. Sci. U.S.A. 98:4658-4663(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700294 / SF370 / Serotype M1.
[2]"Evolutionary origin and emergence of a highly successful clone of serotype M1 group A Streptococcus involved multiple horizontal gene transfer events."
Sumby P., Porcella S.F., Madrigal A.G., Barbian K.D., Virtaneva K., Ricklefs S.M., Sturdevant D.E., Graham M.R., Vuopio-Varkila J., Hoe N.P., Musser J.M.
J. Infect. Dis. 192:771-782(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-947 / MGAS5005 / Serotype M1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE004092 Genomic DNA. Translation: AAK33346.1.
CP000017 Genomic DNA. Translation: AAZ50850.1.
RefSeqNP_268625.1. NC_002737.1.
YP_281595.1. NC_007297.1.

3D structure databases

ProteinModelPortalP66619.
SMRP66619. Positions 10-148.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING160490.SPy_0272.

Chemistry

ChEMBLCHEMBL2364103.

Proteomic databases

PaxDbP66619.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAK33346; AAK33346; SPy_0272.
AAZ50850; AAZ50850; M5005_Spy0231.
GeneID3572698.
900571.
KEGGspy:SPy_0272.
spz:M5005_Spy_0231.
PATRIC19714329. VBIStrPyo79812_0239.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0049.
HOGENOMHOG000039067.
KOK02992.
OMAEVHRMAD.
OrthoDBEOG6P5ZKW.
ProtClustDBPRK05302.

Enzyme and pathway databases

BioCycSPYO160490:GJ81-249-MONOMER.
SPYO293653:GHFC-281-MONOMER.

Family and domain databases

Gene3D1.10.455.10. 1 hit.
HAMAPMF_00480_B. Ribosomal_S7_B.
InterProIPR000235. Ribosomal_S5/S7.
IPR005717. Ribosomal_S7_bac/org-type.
IPR020606. Ribosomal_S7_CS.
IPR023798. Ribosomal_S7_dom.
[Graphical view]
PANTHERPTHR11205. PTHR11205. 1 hit.
PTHR11205:SF13. PTHR11205:SF13. 1 hit.
PfamPF00177. Ribosomal_S7. 1 hit.
[Graphical view]
PIRSFPIRSF002122. RPS7p_RPS7a_RPS5e_RPS7o. 1 hit.
SUPFAMSSF47973. SSF47973. 1 hit.
TIGRFAMsTIGR01029. rpsG_bact. 1 hit.
PROSITEPS00052. RIBOSOMAL_S7. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRS7_STRP1
AccessionPrimary (citable) accession number: P66619
Secondary accession number(s): Q490W8, Q9A1H2
Entry history
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: February 19, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries