P66537 (RS2_MYCTU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
30S ribosomal protein S2

Gene names

Name:	rpsB
Ordered Locus Names:	Rv2890c, MT2958
ORF Names:	MTCY274.21c

Organism

Mycobacterium tuberculosis

Taxonomic identifier

1773 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length	287 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the ribosomal protein S2P family.

Ontologies

Keywords
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	growth Inferred from mutant phenotype. Source: MTBBASE translation Inferred from electronic annotation. Source: InterPro
Cellular component	plasma membrane Inferred from direct assay. Source: MTBBASE small ribosomal subunit Inferred from electronic annotation. Source: InterPro
Molecular function	structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 287	287	30S ribosomal protein S2 HAMAP MF_00291_B		PRO_0000134203

Sequences

	Sequence		Length	Mass (Da)
	P66537 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: 4EAC9F7925046021	FASTA	287	31,089
	10 20 30 40 50 60 MAVVTMKQLL DSGTHFGHQT RRWNPKMKRF IFTDRNGIYI IDLQQTLTFI DKAYEFVKET 70 80 90 100 110 120 VAHGGSVLFV GTKKQAQESV AAEATRVGMP YVNQRWLGGM LTNFSTVHKR LQRLKELEAM 130 140 150 160 170 180 EQTGGFEGRT KKEILGLTRE KNKLERSLGG IRDMAKVPSA IWVVDTNKEH IAVGEARKLG 190 200 210 220 230 240 IPVIAILDTN CDPDEVDYPI PGNDDAIRSA ALLTRVIASA VAEGLQARAG LGRADGKPEA 250 260 270 280 EAAEPLAEWE QELLASATAS ATPSATASTT ALTDAPAGAT EPTTDAS

References

[1]	"Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence." Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E., Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K. , Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J., Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S., Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S., Barrell B.G. Nature 393:537-544(1998) [PubMed: 9634230] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 25618 / H37Rv.
[2]	"Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains." Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O., Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K., Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L., Delcher A., Utterback T.R. , Weidman J.F., Khouri H.M., Gill J., Mikula A., Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M. J. Bacteriol. 184:5479-5490(2002) [PubMed: 12218036] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CDC 1551 / Oshkosh.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX842581 Genomic DNA. Translation: CAA98366.1. AE000516 Genomic DNA. Translation: AAK47283.1.
PIR	E70925.
RefSeq	NP_217406.1. NC_000962.2. NP_337469.1. NC_002755.2.
3D structure databases
ProteinModelPortal	P66537.
SMR	P66537. Positions 6-228.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000003768; EBMYCP00000003768; EBMYCG00000003766. EBMYCT00000072764; EBMYCP00000070823; EBMYCG00000072759.
GeneID	887187. 925322.
GenomeReviews	Gene locus MT2958 in contig AE000516_GR. Gene locus Rv2890c in contig AL123456_GR.
KEGG	mtc:MT2958. mtu:Rv2890c.
PATRIC	18128274. VBIMycTub22151_3236.
TIGR	MT2958.
Organism-specific databases
TubercuList	Rv2890c.
Phylogenomic databases
GeneTree	EBGT00050000017722.
HOGENOM	HBG736296.
OMA	KQAQDSV.
PhylomeDB	P66537.
ProtClustDB	PRK05299.
Family and domain databases
HAMAP	MF_00291_B. Ribosomal_S2_B. [Tree]
InterPro	IPR001865. Ribosomal_S2. IPR005706. Ribosomal_S2_bac/mit/plastid. IPR018130. Ribosomal_S2_CS. IPR023591. Ribosomal_S2_flav_dom. [Graphical view]
KO	K02967.
PANTHER	PTHR12534. Ribosom_S2_bac. 1 hit.
Pfam	PF00318. Ribosomal_S2. 1 hit. [Graphical view]
PRINTS	PR00395. RIBOSOMALS2.
SUPFAM	SSF52313. Ribosomal_S2. 1 hit.
TIGRFAMs	TIGR01011. RpsB_bact. 1 hit.
PROSITE	PS00962. RIBOSOMAL_S2_1. 1 hit. PS00963. RIBOSOMAL_S2_2. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RS2_MYCTU

Accession

Primary (citable) accession number: P66537
Secondary accession number(s): Q10796

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 11, 2004
Last sequence update:	October 11, 2004
Last modified:	January 25, 2012
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program