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P65975 (RECA_BRUME) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein RecA
Alternative name(s):
Recombinase A
Gene names
Name:recA
Ordered Locus Names:BMEI0787
OrganismBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) [Complete proteome] [HAMAP]
Taxonomic identifier224914 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length361 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage By similarity. HAMAP-Rule MF_00268

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00268.

Sequence similarities

Belongs to the RecA family.

Sequence caution

The sequence AAL51968.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processDNA damage
DNA recombination
DNA repair
SOS response
   Cellular componentCytoplasm
   LigandATP-binding
DNA-binding
Nucleotide-binding
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processDNA recombination

Inferred from electronic annotation. Source: UniProtKB-HAMAP

DNA repair

Inferred from electronic annotation. Source: UniProtKB-HAMAP

SOS response

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

DNA-dependent ATPase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

damaged DNA binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

single-stranded DNA binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 361361Protein RecA HAMAP-Rule MF_00268
PRO_0000122671

Regions

Nucleotide binding77 – 848ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
P65975 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: 6E15766D33E5756E

FASTA36138,735
        10         20         30         40         50         60 
MSQNSLRLVE DNSVDKTKAL DAALSQIERA FGKGSIMRLG QNDQVVEIET VSTGSLSLDI 

        70         80         90        100        110        120 
ALGVGGLPKG RIVEIYGPES SGKTTLALHT IAEAQKKGGI CAFVDAEHAL DPVYARKLGV 

       130        140        150        160        170        180 
DLENLLISQP DTGEQALEIT DTLVRSGAID VLVVDSVAAL TPRAEIEGEM GDSLPGLQAR 

       190        200        210        220        230        240 
LMSQALRKLT GSISRSNCMV IFINQIRMKI GVMFGSPETT TGGNALKFYA SVRLDIRRIG 

       250        260        270        280        290        300 
SIKERDEVVG NQTRVKVVKN KLAPPFKQVE FDIMYGAGVS KVGELVDLGV KAGVVEKSGA 

       310        320        330        340        350        360 
WFSYNSQRLG QGRENAKQYL KDNPEVAREI ETTLRQNAGL IAEQFLDDGG PEEDAAGAAE 


M 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE008917 Genomic DNA. Translation: AAL51968.1. Different initiation.
PIRAE3350.
RefSeqNP_539704.2. NC_003317.1.

3D structure databases

ProteinModelPortalP65975.
SMRP65975. Positions 15-336.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING224914.BMEI0787.

Proteomic databases

PRIDEP65975.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAL51968; AAL51968; BMEI0787.
GeneID1196498.
KEGGbme:BMEI0787.
PATRIC17851765. VBIBruMel92729_0886.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000264120.
KOK03553.
OMADYGEQAL.
OrthoDBEOG6ZKXNZ.
ProtClustDBPRK09354.

Family and domain databases

Gene3D3.30.250.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPMF_00268. RecA.
InterProIPR003593. AAA+_ATPase.
IPR013765. DNA_recomb/repair_RecA.
IPR020584. DNA_recomb/repair_RecA_CS.
IPR027417. P-loop_NTPase.
IPR020588. RecA_ATP-bd.
IPR023400. RecA_C.
IPR020587. RecA_monomer-monomer_interface.
[Graphical view]
PANTHERPTHR22942:SF1. PTHR22942:SF1. 1 hit.
PfamPF00154. RecA. 1 hit.
[Graphical view]
PRINTSPR00142. RECA.
SMARTSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
SSF54752. SSF54752. 1 hit.
TIGRFAMsTIGR02012. tigrfam_recA. 1 hit.
PROSITEPS00321. RECA_1. 1 hit.
PS50162. RECA_2. 1 hit.
PS50163. RECA_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROP65975.

Entry information

Entry nameRECA_BRUME
AccessionPrimary (citable) accession number: P65975
Secondary accession number(s): Q8YHL0
Entry history
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: April 16, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Brucella melitensis

Brucella melitensis (strain 16M): entries and gene names