Reviewed, UniProtKB/Swiss-Prot P65862 (PTA_STAAM)

Names and origin

Protein names

Recommended name:
    Phosphate acetyltransferase
    EC=2.3.1.8
Alternative name(s):
    Phosphotransacetylase

Gene names

Name:	pta
Ordered Locus Names:	SAV0588

Organism

Staphylococcus aureus (strain Mu50 / ATCC 700699) [Complete proteome] [HAMAP]

Taxonomic identifier

158878 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	328 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Catalytic activity	Acetyl-CoA + phosphate = CoA + acetyl phosphate.
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 2/2.
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the phosphate acetyltransferase and butyryltransferase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	phosphate acetyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 328	328	Phosphate acetyltransferase		PRO_0000179141

Sequences

	Sequence		Length	Mass (Da)
	P65862-1 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: 7EBE5837CEB3D188	FASTA	328	34,952
	10 20 30 40 50 60 MADLLNVLKD KLSGKNVKIV LPEGEDERVL TAATQLQATD YVTPIVLGDE TKVQSLAQKL 70 80 90 100 110 120 DLDISNIELI NPATSELKAE LVQSFVERRK GKATEEQAQE LLNNVNYFGT MLVYAGKADG 130 140 150 160 170 180 LVSGAAHSTG DTVRPALQII KTKPGVSRTS GIFFMIKGDE QYIFGDCAIN PELDSQGLAE 190 200 210 220 230 240 IAVESAKSAL SFGMDPKVAM LSFSTKGSAK SDDVTKVQEA VKLAQQKAEE EKLEAIIDGE 250 260 270 280 290 300 FQFDAAIVPG VAEKKAPGAK LQGDANVFVF PSLEAGNIGY KIAQRLGGYD AVGPVLQGLN 310 320 SPVNDLSRGC SIEDVYNLSI ITAAQALQ

References

[1]

"Whole genome sequencing of meticillin-resistant Staphylococcus aureus." Kuroda M., Ohta T., Uchiyama I., Baba T., Yuzawa H., Kobayashi I., Cui L., Oguchi A., Aoki K., Nagai Y., Lian J.-Q., Ito T., Kanamori M., Matsumaru H., Maruyama A., Murakami H., Hosoyama A., Mizutani-Ui Y. , Takahashi N.K., Sawano T., Inoue R., Kaito C., Sekimizu K., Hirakawa H., Kuhara S., Goto S., Yabuzaki J., Kanehisa M., Yamashita A., Oshima K., Furuya K., Yoshino C., Shiba T., Hattori M., Ogasawara N., Hayashi H., Hiramatsu K. Lancet 357:1225-1240(2001) [PubMed: 11418146] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000017 Genomic DNA. Translation: BAB56750.1.
RefSeq	NP_371112.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	P65862.
2-D gel databases
World-2DPAGE	0002:P65862.
Genome annotation databases
GeneID	1120561.
GenomeReviews	Gene locus SAV0588 in contig BA000017_GR.
KEGG	sav:SAV0588.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	P65862.
OMA	CSTEDVY.
Enzyme and pathway databases
BioCyc	SAUR158878:SAV0588-MON.
Family and domain databases
InterPro	IPR012147. P_Ac_Bu_trans. IPR004614. P_AcTrfase. IPR002505. PTA_PTB. [Graphical view]
Pfam	PF01515. PTA_PTB. 1 hit. [Graphical view]
PIRSF	PIRSF000428. P_Ac_trans. 1 hit.
TIGRFAMs	TIGR00651. pta. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PTA_STAAM

Accession

Primary (citable) accession number: P65862
Secondary accession number(s): Q99W23

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 11, 2004
Last sequence update:	October 11, 2004
Last modified:	November 3, 2009
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)