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Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Streptococcus agalactiae serotype III (strain NEM316)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei39NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

tRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
Short name:
Psi55 synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:gbs1033
OrganismiStreptococcus agalactiae serotype III (strain NEM316)
Taxonomic identifieri211110 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000000823 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001219101 – 294tRNA pseudouridine synthase BAdd BLAST294

Interactioni

Protein-protein interaction databases

STRINGi211110.gbs1033.

Structurei

3D structure databases

ProteinModelPortaliP65856.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D0T. Bacteria.
COG0130. LUCA.
HOGENOMiHOG000231225.
KOiK03177.
OMAiYELQFIR.

Family and domain databases

HAMAPiMF_01080. TruB_bact. 1 hit.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR002501. PsdUridine_synth_N.
IPR014780. tRNA_psdUridine_synth_TruB.
IPR032819. TruB_C.
[Graphical view]
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiPF16198. TruB_C_2. 1 hit.
PF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00431. TruB. 1 hit.

Sequencei

Sequence statusi: Complete.

P65856-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MITGIINLKK EAGMTSHDAV FKLRKILHTK KIGHGGTLDP DVVGVLPIAV
60 70 80 90 100
GKATRVIEYM TESGKIYEGE ITLGYATSTE DSSGEVISRT PLTQSDLSED
110 120 130 140 150
VVDHAMKSFT GPITQVPPMY SAVKVNGKKL YEYARSGEEV ERPKRQITIS
160 170 180 190 200
EFRRTSPLYF EKGICRFSFY VSCSKGTYVR TLAVDLGIKL GYASHMSFLK
210 220 230 240 250
RTSSAGLSIT QSLTLEEINE KYKQEDFSFL LPIEYGVLDL PKVNLTEEDK
260 270 280 290
VEISYGRRIL LENEADTLAA FYENRVIAIL EKRGNEFKPH KVLL
Length:294
Mass (Da):32,907
Last modified:October 11, 2004 - v1
Checksum:i081E639B31125744
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL766848 Genomic DNA. Translation: CAD46692.1.
RefSeqiWP_001873502.1. NC_004368.1.

Genome annotation databases

EnsemblBacteriaiCAD46692; CAD46692; CAD46692.
KEGGisan:truB.
PATRICi19637936. VBIStrAga3577_1060.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL766848 Genomic DNA. Translation: CAD46692.1.
RefSeqiWP_001873502.1. NC_004368.1.

3D structure databases

ProteinModelPortaliP65856.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi211110.gbs1033.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAD46692; CAD46692; CAD46692.
KEGGisan:truB.
PATRICi19637936. VBIStrAga3577_1060.

Phylogenomic databases

eggNOGiENOG4105D0T. Bacteria.
COG0130. LUCA.
HOGENOMiHOG000231225.
KOiK03177.
OMAiYELQFIR.

Family and domain databases

HAMAPiMF_01080. TruB_bact. 1 hit.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR002501. PsdUridine_synth_N.
IPR014780. tRNA_psdUridine_synth_TruB.
IPR032819. TruB_C.
[Graphical view]
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiPF16198. TruB_C_2. 1 hit.
PF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00431. TruB. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiTRUB_STRA3
AccessioniPrimary (citable) accession number: P65856
Secondary accession number(s): Q8CX11, Q8E5J6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: November 2, 2016
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.