P65801 (GCP_MYCTU) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 50.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp Alternative name(s): t(6)A37 threonylcarbamoyladenosine biosynthesis protein | ||||||
| Gene names |
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| Organism | Mycobacterium tuberculosis | ||||||
| Taxonomic identifier | 1773 [NCBI] | ||||||
| Taxonomic lineage | Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex |
Protein attributes
| Sequence length | 344 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445 |
| Subcellular location | Cytoplasm Potential HAMAP MF_01445. |
| Sequence similarities | Belongs to the KAE1 / YgjD family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | tRNA processing |
| Cellular component | Cytoplasm |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological process | proteolysis Inferred from electronic annotation. Source: InterPro tRNA processingInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 344 | 344 | Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445 | PRO_0000096970 | |||
Sequences
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References
| [1] | "Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence." Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E., Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K. Barrell B.G.Nature 393:537-544(1998) [PubMed: 9634230] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 25618 / H37Rv. |
| [2] | "Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains." Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O., Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K., Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L., Delcher A., Utterback T.R. Fraser C.M.J. Bacteriol. 184:5479-5490(2002) [PubMed: 12218036] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CDC 1551 / Oshkosh. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | BX842583 Genomic DNA. Translation: CAB01004.1. AE000516 Genomic DNA. Translation: AAK47866.1. |
| PIR | H70737. |
| RefSeq | NP_217936.1. NC_000962.2. NP_338052.1. NC_002755.2. |
3D structure databases | |
| ProteinModelPortal | P65801. |
| ModBase | Search... |
Protein family/group databases | |
| MEROPS | M22.A01. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | EBMYCT00000003243; EBMYCP00000003243; EBMYCG00000003241. EBMYCT00000072877; EBMYCP00000070936; EBMYCG00000072872. |
| GeneID | 887595. 923200. |
| GenomeReviews | Gene locus MT3528 in contig AE000516_GR. Gene locus Rv3419c in contig AL123456_GR. |
| KEGG | mtc:MT3528. mtu:Rv3419c. |
| PATRIC | 18129493. VBIMycTub22151_3842. |
| TIGR | MT3528. |
Organism-specific databases | |
| TubercuList | Rv3419c. |
Phylogenomic databases | |
| GeneTree | EBGT00050000017447. |
| HOGENOM | HBG304663. |
| OMA | PLYGVNH. |
| PhylomeDB | P65801. |
| ProtClustDB | PRK09604. |
Family and domain databases | |
| HAMAP | MF_01445. gcp. [Tree] |
| InterPro | IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. [Graphical view] |
| KO | K01409. |
| Pfam | PF00814. Peptidase_M22. 1 hit. [Graphical view] |
| PRINTS | PR00789. OSIALOPTASE. |
| TIGRFAMs | TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit. |
| PROSITE | PS01016. GLYCOPROTEASE. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | GCP_MYCTU | ||||||||
| Accession | Primary (citable) accession number: P65801 Secondary accession number(s): Q50709 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |

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