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P65770 (PPNK2_LISMO) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable inorganic polyphosphate/ATP-NAD kinase 2

Short name=Poly(P)/ATP NAD kinase 2
EC=2.7.1.23
Gene names
Name:ppnK2
Ordered Locus Names:lmo1586
OrganismListeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) [Reference proteome] [HAMAP]
Taxonomic identifier169963 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria

Protein attributes

Sequence length267 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity. HAMAP-Rule MF_00361

Catalytic activity

ATP + NAD+ = ADP + NADP+. HAMAP-Rule MF_00361

Cofactor

Divalent metal ions By similarity. HAMAP-Rule MF_00361

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00361.

Sequence similarities

Belongs to the NAD kinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
NAD
NADP
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processNAD metabolic process

Inferred from electronic annotation. Source: InterPro

NADP biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

NAD+ kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 267267Probable inorganic polyphosphate/ATP-NAD kinase 2 HAMAP-Rule MF_00361
PRO_0000120633

Sequences

Sequence LengthMass (Da)Tools
P65770 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: 69512B6100D49F73

FASTA26730,499
        10         20         30         40         50         60 
MAKTIFYFSY RKTEELHAKA KELKKITTDY GYELTDDYQK ANVIISIGGD GAFLKSVRET 

        70         80         90        100        110        120 
GFRQDCLYAG IALTEQLGQY CDFHINQLDE IIKAAIEDRW LVRRYPTIYG TVNNTKAFYV 

       130        140        150        160        170        180 
LNEFNIRSSI IRTLTMDLYI NDSHFETFRG DGMVISTPTG STAYNKSVNG SIVDPLLPSM 

       190        200        210        220        230        240 
QVSELASINN NKFRTLGSSF ILSPKRKLRI EIASEEGNNE FPMIGMDSEA LSIQHVHEVN 

       250        260 
LEVGDRFINI IKLPKNSFWD KVKRNFL 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL591979 Genomic DNA. Translation: CAC99664.1.
PIRAB1273.
RefSeqNP_465111.1. NC_003210.1.

3D structure databases

ProteinModelPortalP65770.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING169963.lmo1586.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAC99664; CAC99664; CAC99664.
GeneID987765.
KEGGlmo:lmo1586.
PATRIC20312303. VBILisMon69206_1628.

Organism-specific databases

GenoListLMO1586.

Phylogenomic databases

eggNOGCOG0061.
HOGENOMHOG000275803.
KOK00858.
OMADDLHFET.
OrthoDBEOG6PZXDR.
ProtClustDBPRK03501.

Enzyme and pathway databases

BioCycLMON169963:LMO1586-MONOMER.

Family and domain databases

Gene3D2.60.200.30. 1 hit.
3.40.50.10330. 1 hit.
HAMAPMF_00361. NAD_kinase.
InterProIPR017438. ATP-NAD_kinase_dom_1.
IPR016064. ATP-NAD_kinase_PpnK-typ.
IPR017437. ATP-NAD_kinase_PpnK-typ_all-b.
IPR002504. PolyP/ATP_NADK_prd.
[Graphical view]
PANTHERPTHR20275. PTHR20275. 1 hit.
PfamPF01513. NAD_kinase. 1 hit.
[Graphical view]
SUPFAMSSF111331. SSF111331. 1 hit.
ProtoNetSearch...

Entry information

Entry namePPNK2_LISMO
AccessionPrimary (citable) accession number: P65770
Secondary accession number(s): Q92BC2
Entry history
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: February 19, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families