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P65733 (PKNJ_MYCBO) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Serine/threonine-protein kinase PknJ

EC=2.7.11.1
Gene names
Name:pknJ
Ordered Locus Names:Mb2115
OrganismMycobacterium bovis (strain ATCC BAA-935 / AF2122/97) [Complete proteome] [HAMAP]
Taxonomic identifier233413 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex

Protein attributes

Sequence length589 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Subunit structure

Homodimer By similarity.

Subcellular location

Cell membrane; Single-pass membrane protein By similarity.

Sequence similarities

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Contains 1 protein kinase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 589589Serine/threonine-protein kinase PknJ
PRO_0000171221

Regions

Topological domain1 – 342342Cytoplasmic Potential
Transmembrane343 – 36321Helical; Potential
Topological domain364 – 589226Extracellular Potential
Domain14 – 276263Protein kinase
Nucleotide binding20 – 289ATP By similarity

Sites

Active site1361Proton acceptor By similarity
Binding site431ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
P65733 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: E1E179150E2D348E

FASTA58961,595
        10         20         30         40         50         60 
MAHELSAGSV FAGYRIERML GAGGMGTVYL ARNPDLPRSE ALKVLAAELS RDLDFRARFV 

        70         80         90        100        110        120 
READVAAGLD HPNIVAVHQR GQFEGRLWIA MQFVDGGNAE DALRAATMTT ARAVYVIGEV 

       130        140        150        160        170        180 
AKALDYAHQQ GVIHRDIKPA NFLLSRAAGG DERVLLSDFG IARALGDTGL TSTGSVLATL 

       190        200        210        220        230        240 
AYAAPEVLAG QGFDGRADLY SLGCALFRLL TGEAPFAAGA GAAVAVVAGH LHQPPPTVSD 

       250        260        270        280        290        300 
RVPGLSAAMD AVIATAMAKD PMRRFTSAGE FAHAAAAALY GGATDGWVPP SPAPHVISQG 

       310        320        330        340        350        360 
AVPGSPWWQH PVGSVTALAT PPGHGWPPGL PPLPRRPRRY RRGVAAVAAV MVVAAAAVTA 

       370        380        390        400        410        420 
VTMTSHQPRT ATPPSAAALS PTSSSTTPPQ PPIVTRSRLP GLLPPLDDVK NFVGIQNLVA 

       430        440        450        460        470        480 
HEPMLQPQTP NGSINPAECW PAVGGGVPSA YDLGTVIGFY GLTIDEPPTG TAPNQVGQLI 

       490        500        510        520        530        540 
VAFRDAATAQ RHLADLASIW RRCGGRTVTL FRSEWRRPVE LSTSVPEVVD GITTMVLTAQ 

       550        560        570        580 
GPVLRVREDH AIAAKNNVLV DVDIMTPDTS RGQQAVIGIT NYILAKIPG 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX248333 Genomic DNA. Translation: CDO43368.1.
RefSeqNP_855764.1. NC_002945.3.

3D structure databases

ProteinModelPortalP65733.
SMRP65733. Positions 4-340.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING233413.Mb2115.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAD96968; CAD96968; Mb2115.
GeneID1091131.
KEGGmbo:Mb2115.
PATRIC18006356. VBIMycBov88188_2325.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0515.
KOK08884.
OMAARHTEDN.
OrthoDBEOG6B35XT.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR026954. PknH-like_Extracell.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamPF00069. Pkinase. 1 hit.
PF14032. PknH_C. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 2 hits.
PROSITEPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePKNJ_MYCBO
AccessionPrimary (citable) accession number: P65733
Secondary accession number(s): Q10697, X2BK37
Entry history
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: June 11, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families