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P65729

- PKNG_MYCBO

UniProt

P65729 - PKNG_MYCBO

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Protein
Serine/threonine-protein kinase PknG
Gene
pknG, Mb0418c
Organism
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei181 – 1811ATP By similarity
Active sitei276 – 2761Proton acceptor By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi157 – 1659ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. protein serine/threonine kinase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein kinase PknG (EC:2.7.11.1)
Gene namesi
Name:pknG
Ordered Locus Names:Mb0418c
OrganismiMycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Taxonomic identifieri233413 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
ProteomesiUP000001419: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 750750Serine/threonine-protein kinase PknG
PRO_0000171214Add
BLAST

Post-translational modificationi

Autophosphorylated By similarity.

Keywords - PTMi

Phosphoprotein

Interactioni

Protein-protein interaction databases

STRINGi233413.Mb0418c.

Structurei

3D structure databases

ProteinModelPortaliP65729.
SMRiP65729. Positions 74-746.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini151 – 396246Protein kinase
Add
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000049016.
KOiK14949.
OMAiHRYALVD.
OrthoDBiEOG6B35XT.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P65729-1 [UniParc]FASTAAdd to Basket

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MAKASETERS GPGTQPADAQ TATSATVRPL STQAVFRPDF GDEDNFPHPT    50
LGPDTEPQDR MATTSRVRPP VRRLGGGLVE IPRAPDIDPL EALMTNPVVP 100
ESKRFCWNCG RPVGRSDSET KGASEGWCPY CGSPYSFLPQ LNPGDIVAGQ 150
YEVKGCIAHG GLGWIYLALD RNVNGRPVVL KGLVHSGDAE AQAMAMAERQ 200
FLAEVVHPSI VQIFNFVEHT DRHGDPVGYI VMEYVGGQSL KRSKGQKLPV 250
AEAIAYLLEI LPALSYLHSI GLVYNDLKPE NIMLTEEQLK LIDLGAVSRI 300
NSFGYLYGTP GFQAPEIVRT GPTVATDIYT VGRTLAALTL DLPTRNGRYV 350
DGLPEDDPVL KTYDSYGRLL RRAIDPDPRQ RFTTAEEMSA QLTGVLREVV 400
AQDTGVPRPG LSTIFSPSRS TFGVDLLVAH TDVYLDGQVH AEKLTANEIV 450
TALSVPLVDP TDVAASVLQA TVLSQPVQTL DSLRAARHGA LDADGVDFSE 500
SVELPLMEVR ALLDLGDVAK ATRKLDDLAE RVGWRWRLVW YRAVAELLTG 550
DYDSATKHFT EVLDTFPGEL APKLALAATA ELAGNTDEHK FYQTVWSTND 600
GVISAAFGLA RARSAEGDRV GAVRTLDEVP PTSRHFTTAR LTSAVTLLSG 650
RSTSEVTEEQ IRDAARRVEA LPPTEPRVLQ IRALVLGGAL DWLKDNKAST 700
NHILGFPFTS HGLRLGVEAS LRSLARVAPT QRHRYTLVDM ANKVRPTSTF 750
Length:750
Mass (Da):81,577
Last modified:October 11, 2004 - v1
Checksum:iCFC6E54DBE19569F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX248333 Genomic DNA. Translation: CDO41657.1.
RefSeqiNP_854081.1. NC_002945.3.

Genome annotation databases

EnsemblBacteriaiCAD93281; CAD93281; Mb0418c.
GeneIDi1091420.
KEGGimbo:Mb0418c.
PATRICi18002575. VBIMycBov88188_0456.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX248333 Genomic DNA. Translation: CDO41657.1 .
RefSeqi NP_854081.1. NC_002945.3.

3D structure databases

ProteinModelPortali P65729.
SMRi P65729. Positions 74-746.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 233413.Mb0418c.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAD93281 ; CAD93281 ; Mb0418c .
GeneIDi 1091420.
KEGGi mbo:Mb0418c.
PATRICi 18002575. VBIMycBov88188_0456.

Phylogenomic databases

eggNOGi COG0515.
HOGENOMi HOG000049016.
KOi K14949.
OMAi HRYALVD.
OrthoDBi EOG6B35XT.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF00069. Pkinase. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-935 / AF2122/97.

Entry informationi

Entry nameiPKNG_MYCBO
AccessioniPrimary (citable) accession number: P65729
Secondary accession number(s): P96256, X2BEZ4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: June 11, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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