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P65722 (PHS_BRUME) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Putative pterin-4-alpha-carbinolamine dehydratase
Short name=PHS
EC=4.2.1.96
Alternative name(s):
4-alpha-hydroxy-tetrahydropterin dehydratase
Pterin carbinolamine dehydratase
Short name=PCD
Gene names
Name:phhB
Ordered Locus Names:BMEI1864
OrganismBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) [Complete proteome] [HAMAP]
Taxonomic identifier224914 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length97 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

(6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H2O. HAMAP MF_00434

Sequence similarities

Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

Ontologies

Keywords
   Molecular functionLyase
   Technical term3D-structure
Complete proteome
Gene Ontology (GO)
   Biological processtetrahydrobiopterin biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular function4-alpha-hydroxytetrahydrobiopterin dehydratase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 9797Putative pterin-4-alpha-carbinolamine dehydratase HAMAP MF_00434
PRO_0000063076

Secondary structure

1 ................. 97
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P65722 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: 3176828807D408F3

FASTA9711,054
        10         20         30         40         50         60 
MARNRLTESE MNEALRALDG WQKVDGREAI TRSFKFKDFS TAFGFMAQAA LYAEKLDHHP 

        70         80         90 
EWFNAYNRVD VTLATHSENG VTELDIKMAR KMNAIAG

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE008917 Genomic DNA. Translation: AAL53045.1.
PIRAB3485.
RefSeqNP_540781.1. NC_003317.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3JSTX-ray2.10A/B1-97[»]
ProteinModelPortalP65722.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1197575.
GenomeReviewsGene locus BMEI1864 in contig AE008917_GR.
KEGGbme:BMEI1864.
PATRIC17854154. VBIBruMel92729_2062.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG705804.
OMASEERKTR.
PhylomeDBP65722.
ProtClustDBPRK00823.

Enzyme and pathway databases

BioCycBMEL224914:BMEI1864-MONOMER.

Family and domain databases

HAMAPMF_00434. Pterin_4_alpha.
[Tree]
InterProIPR001533. Trans/pterin_deHydtase.
[Graphical view]
Gene3DG3DSA:3.30.1360.20. Trans_pterinDh. 1 hit.
KOK01724.
PANTHERPTHR12599. Trans_pterinDh. 1 hit.
PfamPF01329. Pterin_4a. 1 hit.
[Graphical view]
SUPFAMSSF55248. Trans_pterinDh. 1 hit.
ProtoNetSearch...

Entry information

Entry namePHS_BRUME
AccessionPrimary (citable) accession number: P65722
Secondary accession number(s): Q8YEL4
Entry history
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: January 25, 2012
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Brucella melitensis

Brucella melitensis (strain 16M): entries and gene names

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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