P65644 (EUTT_ECOL6) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ethanolamine utilization cobalamin adenosyltransferase
EC=2.5.1.17

Gene names

Name:	eutT
Ordered Locus Names:	c2984

Organism

Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) [Complete proteome] [HAMAP]

Taxonomic identifier

199310 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	267 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Converts CNB12 to ADOB12 By similarity.
Catalytic activity	ATP + cob(I)yrinic acid a,c-diamide = triphosphate + adenosylcob(III)yrinic acid a,c-diamide. ATP + cobinamide = triphosphate + adenosylcobinamide.
Pathway	Amine and polyamine degradation; ethanolamine degradation.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	cobalamin biosynthetic process Inferred from electronic annotation. Source: InterPro ethanolamine catabolic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW cob(I)yrinic acid a,c-diamide adenosyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 267	267	Ethanolamine utilization cobalamin adenosyltransferase		PRO_0000087099

Sequences

	Sequence		Length	Mass (Da)
	P65644 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: E51EDAB528B4FA76	FASTA	267	30,172
	10 20 30 40 50 60 MKDFITEAWL RANHTLSEGA EIHLPADSRL TPSARELLES RHLRIKFIDE QGRLFVDDEQ 70 80 90 100 110 120 QQPQPVHGLT SSDEHPQACC ELCRQPVAKK PDTLTHLSAE KMVAKSDPRL GFRAVLDSTI 130 140 150 160 170 180 ALAVWLQIEL AEPWQPWLAD IRSRLGNIMR ADALGEPLGC QAIVGLSDED LHRLSHQPLR 190 200 210 220 230 240 YLDHDHLVPE ASHGRDAALL NLLRTKVRET ETVAAQVFIT RSFEVLRPDI LQALNRLSST 250 260 VYVMMILSVT KQPLTVKQIQ QRLGETQ

References

[1]

"Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coli." Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D., Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F., Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T., Donnenberg M.S., Blattner F.R. Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CFT073 / ATCC 700928 / UPEC.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014075 Genomic DNA. Translation: AAN81434.1.
RefSeq	NP_754866.1. NC_004431.1.
3D structure databases
ProteinModelPortal	P65644.
ModBase	Search...
Protein-protein interaction databases
STRING	199310.c2984.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAN81434; AAN81434; c2984.
GeneID	1038632.
KEGG	ecc:c2984.
PATRIC	18283830. VBIEscCol75197_2815.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000289182.
KO	K04032.
OMA	DIMQALN.
ProtClustDB	PRK15020.
Enzyme and pathway databases
UniPathway	UPA00560.
Family and domain databases
Gene3D	1.20.1200.10. 1 hit.
InterPro	IPR016030. AdoCbl_synth_CblAdoTrfase-like. IPR009194. AdoCbl_synth_CblAdoTrfase_EutT. [Graphical view]
Pfam	PF01923. Cob_adeno_trans. 1 hit. [Graphical view]
PIRSF	PIRSF012294. ATR_EutT. 1 hit.
SUPFAM	SSF89028. AdoCbl_synth_CblAdoTrfase-like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

EUTT_ECOL6

Accession

Primary (citable) accession number: P65644
Secondary accession number(s): P76554

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 11, 2004
Last sequence update:	October 11, 2004
Last modified:	May 1, 2013
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program