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P65643

- EUTT_ECOLI

UniProt

P65643 - EUTT_ECOLI

Protein

Ethanolamine utilization cobalamin adenosyltransferase

Gene

eutT

Organism
Escherichia coli (strain K12)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 64 (01 Oct 2014)
      Sequence version 1 (11 Oct 2004)
      Previous versions | rss
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    Functioni

    Converts CNB12 to ADOB12.By similarity

    Catalytic activityi

    ATP + cob(I)yrinic acid a,c-diamide = triphosphate + adenosylcob(III)yrinic acid a,c-diamide.
    ATP + cobinamide = triphosphate + adenosylcobinamide.

    Pathwayi

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. cob(I)yrinic acid a,c-diamide adenosyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. cobalamin biosynthetic process Source: InterPro
    2. ethanolamine catabolic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciEcoCyc:G7289-MONOMER.
    ECOL316407:JW2443-MONOMER.
    UniPathwayiUPA00560.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ethanolamine utilization cobalamin adenosyltransferase (EC:2.5.1.17)
    Gene namesi
    Name:eutT
    Synonyms:ypfB
    Ordered Locus Names:b2459, JW2443
    OrganismiEscherichia coli (strain K12)
    Taxonomic identifieri83333 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000000318: Chromosome, UP000000625: Chromosome

    Organism-specific databases

    EcoGeneiEG14189. eutT.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 267267Ethanolamine utilization cobalamin adenosyltransferasePRO_0000087100Add
    BLAST

    Expressioni

    Gene expression databases

    GenevestigatoriP65643.

    Interactioni

    Protein-protein interaction databases

    DIPiDIP-9543N.
    IntActiP65643. 7 interactions.
    STRINGi511145.b2459.

    Structurei

    3D structure databases

    ProteinModelPortaliP65643.
    SMRiP65643. Positions 104-248.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiCOG4812.
    HOGENOMiHOG000289182.
    KOiK04032.
    OMAiACCELCH.
    OrthoDBiEOG6FRCTX.

    Family and domain databases

    Gene3Di1.20.1200.10. 1 hit.
    InterProiIPR016030. AdoCbl_synth_CblAdoTrfase-like.
    IPR009194. AdoCbl_synth_CblAdoTrfase_EutT.
    [Graphical view]
    PfamiPF01923. Cob_adeno_trans. 1 hit.
    [Graphical view]
    PIRSFiPIRSF012294. ATR_EutT. 1 hit.
    SUPFAMiSSF89028. SSF89028. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P65643-1 [UniParc]FASTAAdd to Basket

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    MKDFITEAWL RANHTLSEGA EIHLPADSRL TPSARELLES RHLRIKFIDE    50
    QGRLFVDDEQ QQPQPVHGLT SSDEHPQACC ELCRQPVAKK PDTLTHLSAE 100
    KMVAKSDPRL GFRAVLDSTI ALAVWLQIEL AEPWQPWLAD IRSRLGNIMR 150
    ADALGEPLGC QAIVGLSDED LHRLSHQPLR YLDHDHLVPE ASHGRDAALL 200
    NLLRTKVRET ETVAAQVFIT RSFEVLRPDI LQALNRLSST VYVMMILSVT 250
    KQPLTVKQIQ QRLGETQ 267
    Length:267
    Mass (Da):30,172
    Last modified:October 11, 2004 - v1
    Checksum:iE51EDAB528B4FA76
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U00096 Genomic DNA. Translation: AAC75512.1.
    AP009048 Genomic DNA. Translation: BAE76717.1.
    PIRiB65021.
    RefSeqiNP_416954.1. NC_000913.3.
    YP_490686.1. NC_007779.1.

    Genome annotation databases

    EnsemblBacteriaiAAC75512; AAC75512; b2459.
    BAE76717; BAE76717; BAE76717.
    GeneIDi12931925.
    946939.
    KEGGiecj:Y75_p2411.
    eco:b2459.
    PATRICi32120301. VBIEscCol129921_2553.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U00096 Genomic DNA. Translation: AAC75512.1 .
    AP009048 Genomic DNA. Translation: BAE76717.1 .
    PIRi B65021.
    RefSeqi NP_416954.1. NC_000913.3.
    YP_490686.1. NC_007779.1.

    3D structure databases

    ProteinModelPortali P65643.
    SMRi P65643. Positions 104-248.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    DIPi DIP-9543N.
    IntActi P65643. 7 interactions.
    STRINGi 511145.b2459.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC75512 ; AAC75512 ; b2459 .
    BAE76717 ; BAE76717 ; BAE76717 .
    GeneIDi 12931925.
    946939.
    KEGGi ecj:Y75_p2411.
    eco:b2459.
    PATRICi 32120301. VBIEscCol129921_2553.

    Organism-specific databases

    EchoBASEi EB3941.
    EcoGenei EG14189. eutT.

    Phylogenomic databases

    eggNOGi COG4812.
    HOGENOMi HOG000289182.
    KOi K04032.
    OMAi ACCELCH.
    OrthoDBi EOG6FRCTX.

    Enzyme and pathway databases

    UniPathwayi UPA00560 .
    BioCyci EcoCyc:G7289-MONOMER.
    ECOL316407:JW2443-MONOMER.

    Miscellaneous databases

    PROi P65643.

    Gene expression databases

    Genevestigatori P65643.

    Family and domain databases

    Gene3Di 1.20.1200.10. 1 hit.
    InterProi IPR016030. AdoCbl_synth_CblAdoTrfase-like.
    IPR009194. AdoCbl_synth_CblAdoTrfase_EutT.
    [Graphical view ]
    Pfami PF01923. Cob_adeno_trans. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF012294. ATR_EutT. 1 hit.
    SUPFAMi SSF89028. SSF89028. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / MG1655 / ATCC 47076.
    2. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
      Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
      Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

    Entry informationi

    Entry nameiEUTT_ECOLI
    AccessioniPrimary (citable) accession number: P65643
    Secondary accession number(s): P76554, Q2MAI9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 11, 2004
    Last sequence update: October 11, 2004
    Last modified: October 1, 2014
    This is version 64 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Escherichia coli
      Escherichia coli (strain K12): entries and cross-references to EcoGene
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways

    External Data

    Dasty 3