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Protein

Ethanolamine utilization cobalamin adenosyltransferase

Gene

eutT

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Converts CNB12 to ADOB12.By similarity

Catalytic activityi

ATP + cob(I)yrinic acid a,c-diamide = triphosphate + adenosylcob(III)yrinic acid a,c-diamide.
ATP + cobinamide = triphosphate + adenosylcobinamide.

Pathwayi: ethanolamine degradation

This protein is involved in the pathway ethanolamine degradation, which is part of Amine and polyamine degradation.
View all proteins of this organism that are known to be involved in the pathway ethanolamine degradation and in Amine and polyamine degradation.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciEcoCyc:G7289-MONOMER
UniPathwayiUPA00560

Names & Taxonomyi

Protein namesi
Recommended name:
Ethanolamine utilization cobalamin adenosyltransferase (EC:2.5.1.17)
Gene namesi
Name:eutT
Synonyms:ypfB
Ordered Locus Names:b2459, JW2443
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG14189 eutT

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000871001 – 267Ethanolamine utilization cobalamin adenosyltransferaseAdd BLAST267

Proteomic databases

PaxDbiP65643
PRIDEiP65643

Interactioni

Protein-protein interaction databases

BioGridi4260919, 3 interactors
DIPiDIP-9543N
IntActiP65643, 7 interactors
STRINGi316385.ECDH10B_2624

Structurei

3D structure databases

ProteinModelPortaliP65643
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4108PFF Bacteria
COG4812 LUCA
HOGENOMiHOG000289182
InParanoidiP65643
KOiK04032
OMAiACCELCH

Family and domain databases

Gene3Di1.20.1200.10, 1 hit
InterProiView protein in InterPro
IPR009194 AdoCbl_synth_CblAdoTrfase_EutT
IPR016030 CblAdoTrfase-like
IPR036451 CblAdoTrfase-like_sf
PfamiView protein in Pfam
PF01923 Cob_adeno_trans, 1 hit
PIRSFiPIRSF012294 ATR_EutT, 1 hit
SUPFAMiSSF89028 SSF89028, 1 hit

Sequencei

Sequence statusi: Complete.

P65643-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKDFITEAWL RANHTLSEGA EIHLPADSRL TPSARELLES RHLRIKFIDE
60 70 80 90 100
QGRLFVDDEQ QQPQPVHGLT SSDEHPQACC ELCRQPVAKK PDTLTHLSAE
110 120 130 140 150
KMVAKSDPRL GFRAVLDSTI ALAVWLQIEL AEPWQPWLAD IRSRLGNIMR
160 170 180 190 200
ADALGEPLGC QAIVGLSDED LHRLSHQPLR YLDHDHLVPE ASHGRDAALL
210 220 230 240 250
NLLRTKVRET ETVAAQVFIT RSFEVLRPDI LQALNRLSST VYVMMILSVT
260
KQPLTVKQIQ QRLGETQ
Length:267
Mass (Da):30,172
Last modified:October 11, 2004 - v1
Checksum:iE51EDAB528B4FA76
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC75512.1
AP009048 Genomic DNA Translation: BAE76717.1
PIRiB65021
RefSeqiNP_416954.1, NC_000913.3
WP_000651298.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC75512; AAC75512; b2459
BAE76717; BAE76717; BAE76717
GeneIDi946939
KEGGiecj:JW2443
eco:b2459
PATRICifig|1411691.4.peg.4281

Similar proteinsi

Entry informationi

Entry nameiEUTT_ECOLI
AccessioniPrimary (citable) accession number: P65643
Secondary accession number(s): P76554, Q2MAI9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: March 28, 2018
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways

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