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P65643

- EUTT_ECOLI

UniProt

P65643 - EUTT_ECOLI

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Protein
Ethanolamine utilization cobalamin adenosyltransferase
Gene
eutT, ypfB, b2459, JW2443
Organism
Escherichia coli (strain K12)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Converts CNB12 to ADOB12 By similarity.

Catalytic activityi

ATP + cob(I)yrinic acid a,c-diamide = triphosphate + adenosylcob(III)yrinic acid a,c-diamide.
ATP + cobinamide = triphosphate + adenosylcobinamide.

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. cob(I)yrinic acid a,c-diamide adenosyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. cobalamin biosynthetic process Source: InterPro
  2. ethanolamine catabolic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciEcoCyc:G7289-MONOMER.
ECOL316407:JW2443-MONOMER.
UniPathwayiUPA00560.

Names & Taxonomyi

Protein namesi
Recommended name:
Ethanolamine utilization cobalamin adenosyltransferase (EC:2.5.1.17)
Gene namesi
Name:eutT
Synonyms:ypfB
Ordered Locus Names:b2459, JW2443
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000000318: Chromosome, UP000000625: Chromosome

Organism-specific databases

EcoGeneiEG14189. eutT.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 267267Ethanolamine utilization cobalamin adenosyltransferase
PRO_0000087100Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriP65643.

Interactioni

Protein-protein interaction databases

DIPiDIP-9543N.
IntActiP65643. 7 interactions.
STRINGi511145.b2459.

Structurei

3D structure databases

ProteinModelPortaliP65643.
SMRiP65643. Positions 104-248.

Family & Domainsi

Phylogenomic databases

eggNOGiCOG4812.
HOGENOMiHOG000289182.
KOiK04032.
OMAiACCELCH.
OrthoDBiEOG6FRCTX.

Family and domain databases

Gene3Di1.20.1200.10. 1 hit.
InterProiIPR016030. AdoCbl_synth_CblAdoTrfase-like.
IPR009194. AdoCbl_synth_CblAdoTrfase_EutT.
[Graphical view]
PfamiPF01923. Cob_adeno_trans. 1 hit.
[Graphical view]
PIRSFiPIRSF012294. ATR_EutT. 1 hit.
SUPFAMiSSF89028. SSF89028. 1 hit.

Sequencei

Sequence statusi: Complete.

P65643-1 [UniParc]FASTAAdd to Basket

« Hide

MKDFITEAWL RANHTLSEGA EIHLPADSRL TPSARELLES RHLRIKFIDE    50
QGRLFVDDEQ QQPQPVHGLT SSDEHPQACC ELCRQPVAKK PDTLTHLSAE 100
KMVAKSDPRL GFRAVLDSTI ALAVWLQIEL AEPWQPWLAD IRSRLGNIMR 150
ADALGEPLGC QAIVGLSDED LHRLSHQPLR YLDHDHLVPE ASHGRDAALL 200
NLLRTKVRET ETVAAQVFIT RSFEVLRPDI LQALNRLSST VYVMMILSVT 250
KQPLTVKQIQ QRLGETQ 267
Length:267
Mass (Da):30,172
Last modified:October 11, 2004 - v1
Checksum:iE51EDAB528B4FA76
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U00096 Genomic DNA. Translation: AAC75512.1.
AP009048 Genomic DNA. Translation: BAE76717.1.
PIRiB65021.
RefSeqiNP_416954.1. NC_000913.3.
YP_490686.1. NC_007779.1.

Genome annotation databases

EnsemblBacteriaiAAC75512; AAC75512; b2459.
BAE76717; BAE76717; BAE76717.
GeneIDi12931925.
946939.
KEGGiecj:Y75_p2411.
eco:b2459.
PATRICi32120301. VBIEscCol129921_2553.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U00096 Genomic DNA. Translation: AAC75512.1 .
AP009048 Genomic DNA. Translation: BAE76717.1 .
PIRi B65021.
RefSeqi NP_416954.1. NC_000913.3.
YP_490686.1. NC_007779.1.

3D structure databases

ProteinModelPortali P65643.
SMRi P65643. Positions 104-248.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

DIPi DIP-9543N.
IntActi P65643. 7 interactions.
STRINGi 511145.b2459.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC75512 ; AAC75512 ; b2459 .
BAE76717 ; BAE76717 ; BAE76717 .
GeneIDi 12931925.
946939.
KEGGi ecj:Y75_p2411.
eco:b2459.
PATRICi 32120301. VBIEscCol129921_2553.

Organism-specific databases

EchoBASEi EB3941.
EcoGenei EG14189. eutT.

Phylogenomic databases

eggNOGi COG4812.
HOGENOMi HOG000289182.
KOi K04032.
OMAi ACCELCH.
OrthoDBi EOG6FRCTX.

Enzyme and pathway databases

UniPathwayi UPA00560 .
BioCyci EcoCyc:G7289-MONOMER.
ECOL316407:JW2443-MONOMER.

Miscellaneous databases

PROi P65643.

Gene expression databases

Genevestigatori P65643.

Family and domain databases

Gene3Di 1.20.1200.10. 1 hit.
InterProi IPR016030. AdoCbl_synth_CblAdoTrfase-like.
IPR009194. AdoCbl_synth_CblAdoTrfase_EutT.
[Graphical view ]
Pfami PF01923. Cob_adeno_trans. 1 hit.
[Graphical view ]
PIRSFi PIRSF012294. ATR_EutT. 1 hit.
SUPFAMi SSF89028. SSF89028. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  2. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiEUTT_ECOLI
AccessioniPrimary (citable) accession number: P65643
Secondary accession number(s): P76554, Q2MAI9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: May 14, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways

External Data

Dasty 3

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