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P65611

- PYRB_BRUME

UniProt

P65611 - PYRB_BRUME

Protein

Aspartate carbamoyltransferase

Gene

pyrB

Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 66 (01 Oct 2014)
      Sequence version 1 (11 Oct 2004)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. amino acid binding Source: InterPro
    2. aspartate carbamoyltransferase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. 'de novo' pyrimidine nucleobase biosynthetic process Source: InterPro
    2. 'de novo' UMP biosynthetic process Source: UniProtKB-UniPathway
    3. cellular amino acid metabolic process Source: InterPro

    Keywords - Molecular functioni

    Transferase

    Keywords - Biological processi

    Pyrimidine biosynthesis

    Enzyme and pathway databases

    UniPathwayiUPA00070; UER00116.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Aspartate carbamoyltransferaseUniRule annotation (EC:2.1.3.2UniRule annotation)
    Alternative name(s):
    Aspartate transcarbamylaseUniRule annotation
    Short name:
    ATCaseUniRule annotation
    Gene namesi
    Name:pyrBUniRule annotation
    Ordered Locus Names:BMEII0670
    OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
    Taxonomic identifieri224914 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000000419: Chromosome II

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 322322Aspartate carbamoyltransferasePRO_0000113108Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi224914.BMEII0670.

    Structurei

    3D structure databases

    ProteinModelPortaliP65611.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ATCase/OTCase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000022685.
    KOiK00609.
    OMAiMTLNAMR.
    OrthoDBiEOG61KBJZ.

    Family and domain databases

    Gene3Di3.40.50.1370. 2 hits.
    HAMAPiMF_00001. Asp_carb_tr.
    InterProiIPR006132. Asp/Orn_carbamoyltranf_P-bd.
    IPR006130. Asp/Orn_carbamoylTrfase.
    IPR002082. Asp_carbamoyltransf.
    IPR006131. Asp_carbamoyltransf_Asp/Orn-bd.
    [Graphical view]
    PfamiPF00185. OTCace. 1 hit.
    PF02729. OTCace_N. 1 hit.
    [Graphical view]
    PRINTSiPR00100. AOTCASE.
    PR00101. ATCASE.
    SUPFAMiSSF53671. SSF53671. 1 hit.
    TIGRFAMsiTIGR00670. asp_carb_tr. 1 hit.
    PROSITEiPS00097. CARBAMOYLTRANSFERASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P65611-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTNQTVSPLF PHRHLLGIKG LSPLDILCLL DLADQEIAVS RQPEKKKSVL    50
    RGRTQINLFF EASTRTQSSF ELAGKRLGAD VMNMSVGNSS VKKGETLIDT 100
    AMTLNAMQPD ILVIRHASAG AAALLAQKVG CSVVNAGDGA HEHPTQALLD 150
    ALTIRRAKGQ IENLIVAICG DVLHSRVARS NILLLNALGA RVRVVAPSTL 200
    LPAGMADMSV EVFNSMEEGL KDADVVMMLR LQRERMAGSF VPSVREYFHF 250
    YGLDREKLKF AKPDALVMHP GPMNRGVEIA SDVADGPQSV IQQQVEMGVA 300
    VRMAVMEALL DPRRNPGNGE PA 322
    Length:322
    Mass (Da):34,802
    Last modified:October 11, 2004 - v1
    Checksum:i81B6208851B9521B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE008918 Genomic DNA. Translation: AAL53912.1.
    PIRiAE3593.
    RefSeqiNP_541648.1. NC_003318.1.

    Genome annotation databases

    EnsemblBacteriaiAAL53912; AAL53912; BMEII0670.
    GeneIDi1198442.
    KEGGibme:BMEII0670.
    PATRICi17799738. VBIBruMel146950_2205.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE008918 Genomic DNA. Translation: AAL53912.1 .
    PIRi AE3593.
    RefSeqi NP_541648.1. NC_003318.1.

    3D structure databases

    ProteinModelPortali P65611.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 224914.BMEII0670.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAL53912 ; AAL53912 ; BMEII0670 .
    GeneIDi 1198442.
    KEGGi bme:BMEII0670.
    PATRICi 17799738. VBIBruMel146950_2205.

    Phylogenomic databases

    HOGENOMi HOG000022685.
    KOi K00609.
    OMAi MTLNAMR.
    OrthoDBi EOG61KBJZ.

    Enzyme and pathway databases

    UniPathwayi UPA00070 ; UER00116 .

    Miscellaneous databases

    PROi P65611.

    Family and domain databases

    Gene3Di 3.40.50.1370. 2 hits.
    HAMAPi MF_00001. Asp_carb_tr.
    InterProi IPR006132. Asp/Orn_carbamoyltranf_P-bd.
    IPR006130. Asp/Orn_carbamoylTrfase.
    IPR002082. Asp_carbamoyltransf.
    IPR006131. Asp_carbamoyltransf_Asp/Orn-bd.
    [Graphical view ]
    Pfami PF00185. OTCace. 1 hit.
    PF02729. OTCace_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00100. AOTCASE.
    PR00101. ATCASE.
    SUPFAMi SSF53671. SSF53671. 1 hit.
    TIGRFAMsi TIGR00670. asp_carb_tr. 1 hit.
    PROSITEi PS00097. CARBAMOYLTRANSFERASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 16M / ATCC 23456 / NCTC 10094.

    Entry informationi

    Entry nameiPYRB_BRUME
    AccessioniPrimary (citable) accession number: P65611
    Secondary accession number(s): Q8YC62
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 11, 2004
    Last sequence update: October 11, 2004
    Last modified: October 1, 2014
    This is version 66 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Brucella melitensis
      Brucella melitensis (strain 16M): entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3