SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P65611

- PYRB_BRUME

UniProt

P65611 - PYRB_BRUME

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Aspartate carbamoyltransferase
Gene
pyrB, BMEII0670
Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. amino acid binding Source: InterPro
  2. aspartate carbamoyltransferase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 'de novo' UMP biosynthetic process Source: UniProtKB-UniPathway
  2. 'de novo' pyrimidine nucleobase biosynthetic process Source: InterPro
  3. cellular amino acid metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Pyrimidine biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00070; UER00116.

Names & Taxonomyi

Protein namesi
Recommended name:
Aspartate carbamoyltransferase (EC:2.1.3.2)
Alternative name(s):
Aspartate transcarbamylase
Short name:
ATCase
Gene namesi
Name:pyrB
Ordered Locus Names:BMEII0670
OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Taxonomic identifieri224914 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000000419: Chromosome II

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 322322Aspartate carbamoyltransferaseUniRule annotation
PRO_0000113108Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi224914.BMEII0670.

Structurei

3D structure databases

ProteinModelPortaliP65611.

Family & Domainsi

Sequence similaritiesi

Belongs to the ATCase/OTCase family.

Phylogenomic databases

HOGENOMiHOG000022685.
KOiK00609.
OMAiMTLNAMR.
OrthoDBiEOG61KBJZ.

Family and domain databases

Gene3Di3.40.50.1370. 2 hits.
HAMAPiMF_00001. Asp_carb_tr.
InterProiIPR006132. Asp/Orn_carbamoyltranf_P-bd.
IPR006130. Asp/Orn_carbamoylTrfase.
IPR002082. Asp_carbamoyltransf.
IPR006131. Asp_carbamoyltransf_Asp/Orn-bd.
[Graphical view]
PfamiPF00185. OTCace. 1 hit.
PF02729. OTCace_N. 1 hit.
[Graphical view]
PRINTSiPR00100. AOTCASE.
PR00101. ATCASE.
SUPFAMiSSF53671. SSF53671. 1 hit.
TIGRFAMsiTIGR00670. asp_carb_tr. 1 hit.
PROSITEiPS00097. CARBAMOYLTRANSFERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P65611-1 [UniParc]FASTAAdd to Basket

« Hide

MTNQTVSPLF PHRHLLGIKG LSPLDILCLL DLADQEIAVS RQPEKKKSVL    50
RGRTQINLFF EASTRTQSSF ELAGKRLGAD VMNMSVGNSS VKKGETLIDT 100
AMTLNAMQPD ILVIRHASAG AAALLAQKVG CSVVNAGDGA HEHPTQALLD 150
ALTIRRAKGQ IENLIVAICG DVLHSRVARS NILLLNALGA RVRVVAPSTL 200
LPAGMADMSV EVFNSMEEGL KDADVVMMLR LQRERMAGSF VPSVREYFHF 250
YGLDREKLKF AKPDALVMHP GPMNRGVEIA SDVADGPQSV IQQQVEMGVA 300
VRMAVMEALL DPRRNPGNGE PA 322
Length:322
Mass (Da):34,802
Last modified:October 11, 2004 - v1
Checksum:i81B6208851B9521B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE008918 Genomic DNA. Translation: AAL53912.1.
PIRiAE3593.
RefSeqiNP_541648.1. NC_003318.1.

Genome annotation databases

EnsemblBacteriaiAAL53912; AAL53912; BMEII0670.
GeneIDi1198442.
KEGGibme:BMEII0670.
PATRICi17799738. VBIBruMel146950_2205.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE008918 Genomic DNA. Translation: AAL53912.1 .
PIRi AE3593.
RefSeqi NP_541648.1. NC_003318.1.

3D structure databases

ProteinModelPortali P65611.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 224914.BMEII0670.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAL53912 ; AAL53912 ; BMEII0670 .
GeneIDi 1198442.
KEGGi bme:BMEII0670.
PATRICi 17799738. VBIBruMel146950_2205.

Phylogenomic databases

HOGENOMi HOG000022685.
KOi K00609.
OMAi MTLNAMR.
OrthoDBi EOG61KBJZ.

Enzyme and pathway databases

UniPathwayi UPA00070 ; UER00116 .

Miscellaneous databases

PROi P65611.

Family and domain databases

Gene3Di 3.40.50.1370. 2 hits.
HAMAPi MF_00001. Asp_carb_tr.
InterProi IPR006132. Asp/Orn_carbamoyltranf_P-bd.
IPR006130. Asp/Orn_carbamoylTrfase.
IPR002082. Asp_carbamoyltransf.
IPR006131. Asp_carbamoyltransf_Asp/Orn-bd.
[Graphical view ]
Pfami PF00185. OTCace. 1 hit.
PF02729. OTCace_N. 1 hit.
[Graphical view ]
PRINTSi PR00100. AOTCASE.
PR00101. ATCASE.
SUPFAMi SSF53671. SSF53671. 1 hit.
TIGRFAMsi TIGR00670. asp_carb_tr. 1 hit.
PROSITEi PS00097. CARBAMOYLTRANSFERASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 16M / ATCC 23456 / NCTC 10094.

Entry informationi

Entry nameiPYRB_BRUME
AccessioniPrimary (citable) accession number: P65611
Secondary accession number(s): Q8YC62
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: May 14, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella melitensis
    Brucella melitensis (strain 16M): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi