P65500 (NADB_MYCBO) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 50.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: L-aspartate oxidase Short name=LASPO EC=1.4.3.16 Alternative name(s): Quinolinate synthase B | ||||
| Gene names |
| ||||
| Organism | Mycobacterium bovis [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 1765 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex |
Protein attributes
| Sequence length | 527 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Catalyzes the oxidation of L-aspartate to iminoaspartate. |
| Catalytic activity | L-aspartate + O2 = iminosuccinate + H2O2. |
| Cofactor | FAD. |
| Pathway | |
| Subcellular location | Cytoplasm By similarity. |
| Sequence similarities | Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Pyridine nucleotide biosynthesis |
| Cellular component | Cytoplasm |
| Ligand | FAD Flavoprotein |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | NAD biosynthetic process Inferred from electronic annotation. Source: InterPro |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | L-aspartate oxidase activity Inferred from electronic annotation. Source: EC L-aspartate:fumarate oxidoreductase activityInferred from electronic annotation. Source: EC electron carrier activityInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
| ||||||||||||||||||
References
| [1] | "The complete genome sequence of Mycobacterium bovis." Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M., Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B., Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J. Hewinson R.G.Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003) [PubMed: 12788972] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-935 / AF2122/97. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | BX248339 Genomic DNA. Translation: CAD96289.1. |
| RefSeq | NP_855274.1. NC_002945.3. |
3D structure databases | |
| ProteinModelPortal | P65500. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | EBMYCT00000016163; EBMYCP00000015998; EBMYCG00000016158. |
| GeneID | 1092510. |
| GenomeReviews | Gene locus Mb1621 in contig BX248333_GR. |
| KEGG | mbo:Mb1621. |
| PATRIC | 18005245. VBIMycBov88188_1770. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| GeneTree | EBGT00050000015552. |
| HOGENOM | HBG293998. |
| OMA | GAYIWNR. |
| ProtClustDB | PRK07804. |
Enzyme and pathway databases | |
| BioCyc | MBOV233413:MB1621-MONOMER. |
Family and domain databases | |
| InterPro | IPR003953. FAD_bind2_N. IPR013027. FAD_pyr_nucl-diS_OxRdtase. IPR015939. Fum_Rdtase/Succ_DH_flav-like_C. IPR004112. Fum_Rdtase/Succ_DH_flav_C. IPR005288. NadB. [Graphical view] |
| Gene3D | G3DSA:1.20.58.100. Fum_Rdtase/Succ_DH_flav-like_C. 1 hit. |
| KO | K00278. |
| Pfam | PF00890. FAD_binding_2. 1 hit. PF02910. Succ_DH_flav_C. 1 hit. [Graphical view] |
| PRINTS | PR00368. FADPNR. |
| SUPFAM | SSF46977. Succ_DH_flav_C. 1 hit. |
| TIGRFAMs | TIGR00551. NadB. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | NADB_MYCBO | ||||||||
| Accession | Primary (citable) accession number: P65500 Secondary accession number(s): O06595 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with