P65451 (MSRB_STAAM) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 50.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Peptide methionine sulfoxide reductase MsrB EC=1.8.4.12 Alternative name(s): Peptide-methionine (R)-S-oxide reductase | ||||
| Gene names |
| ||||
| Organism | Staphylococcus aureus (strain Mu50 / ATCC 700699) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 158878 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Firmicutes › Bacillales › Staphylococcus |
Protein attributes
| Sequence length | 142 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at protein level |
General annotation (Comments)
| Catalytic activity | Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin. HAMAP MF_01400 |
| Sequence similarities | Belongs to the MsrB Met sulfoxide reductase family. |
Ontologies
| Keywords | |
|---|---|
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Molecular function | peptide-methionine (R)-S-oxide reductase activity Inferred from electronic annotation. Source: EC peptide-methionine-(S)-S-oxide reductase activityInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 142 | 142 | Peptide methionine sulfoxide reductase MsrB HAMAP MF_01400 | PRO_0000140295 | |||||
Sites | |||||||||
| Active site | 114 | 1 | Nucleophile By similarity | ||||||
Sequences
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References
| [1] | "Whole genome sequencing of meticillin-resistant Staphylococcus aureus." Kuroda M., Ohta T., Uchiyama I., Baba T., Yuzawa H., Kobayashi I., Cui L., Oguchi A., Aoki K., Nagai Y., Lian J.-Q., Ito T., Kanamori M., Matsumaru H., Maruyama A., Murakami H., Hosoyama A., Mizutani-Ui Y. Hiramatsu K.Lancet 357:1225-1240(2001) [PubMed: 11418146] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Mu50 / ATCC 700699. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | BA000017 Genomic DNA. Translation: BAB57585.1. |
| RefSeq | NP_371947.1. NC_002758.2. |
3D structure databases | |
| ProteinModelPortal | P65451. |
| SMR | P65451. Positions 9-142. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | P65451. |
2D gel databases | |
| World-2DPAGE | 0002:P65451. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | EBSTAT00000005712; EBSTAP00000005530; EBSTAG00000005711. |
| GeneID | 1121398. |
| GenomeReviews | Gene locus SAV1423 in contig BA000017_GR. |
| KEGG | sav:SAV1423. |
| PATRIC | 19563570. VBIStaAur52173_1462. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG0229. |
| GeneTree | EBGT00050000024012. |
| HOGENOM | HBG715255. |
| OMA | FTDGPVD. |
| PhylomeDB | P65451. |
| ProtClustDB | PRK00222. |
Enzyme and pathway databases | |
| BioCyc | SAUR158878:SAV1423-MONOMER. |
Family and domain databases | |
| HAMAP | MF_01400. MsrB. [Tree] |
| InterPro | IPR002579. Methionine_sulphoxide_MsrB. IPR011057. Mss4-like. [Graphical view] |
| Gene3D | G3DSA:2.170.150.20. MsrB. 1 hit. |
| KO | K07305. |
| Pfam | PF01641. SelR. 1 hit. [Graphical view] |
| SUPFAM | SSF51316. Mss4_like. 1 hit. |
| TIGRFAMs | TIGR00357. TIGR00357. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | MSRB_STAAM | ||||||||
| Accession | Primary (citable) accession number: P65451 Secondary accession number(s): Q99U64 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |

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