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Protein

Septum site-determining protein MinC

Gene

minC

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.UniRule annotation

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, Septation

Enzyme and pathway databases

BioCyciSENT99287:G1FZD-1830-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Septum site-determining protein MinC
Gene namesi
Name:minCUniRule annotation
Ordered Locus Names:STM1814
OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Taxonomic identifieri99287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella
Proteomesi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001890601 – 235Septum site-determining protein MinCAdd BLAST235

Proteomic databases

PaxDbiP65359
PRIDEiP65359

Interactioni

Subunit structurei

Interacts with MinD and FtsZ.UniRule annotation

Protein-protein interaction databases

STRINGi99287.STM1814

Structurei

Secondary structure

1235
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi16 – 22Combined sources7
Helixi25 – 38Combined sources14
Helixi40 – 43Combined sources4
Beta strandi47 – 54Combined sources8
Helixi61 – 69Combined sources9
Turni70 – 72Combined sources3
Beta strandi74 – 80Combined sources7
Helixi84 – 92Combined sources9

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3GHFX-ray2.20A2-110[»]
ProteinModelPortaliP65359
SMRiP65359
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP65359

Family & Domainsi

Sequence similaritiesi

Belongs to the MinC family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105K7U Bacteria
COG0850 LUCA
HOGENOMiHOG000062060
KOiK03610
OMAiRRDPLWG
PhylomeDBiP65359

Family and domain databases

Gene3Di2.160.20.70, 1 hit
3.30.750.120, 1 hit
HAMAPiMF_00267 MinC, 1 hit
InterProiView protein in InterPro
IPR016098 CAP/MinC_C
IPR013033 MinC
IPR036145 MinC_C_sf
IPR007874 MinC_N
IPR038061 MinC_Proteobac_N_sf
IPR005526 Septum_form_inhib_MinC_C
PANTHERiPTHR34108 PTHR34108, 1 hit
PfamiView protein in Pfam
PF03775 MinC_C, 1 hit
PF05209 MinC_N, 1 hit
SUPFAMiSSF63848 SSF63848, 1 hit
TIGRFAMsiTIGR01222 minC, 1 hit

Sequencei

Sequence statusi: Complete.

P65359-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNTPIELKG SSFTLSVVHL HEAEPEVIRQ ALEDKIAQAP AFLKHAPVVI
60 70 80 90 100
NVSGLESPVN WPELHKIVTS TGLRIIGVSG CKDASLKVEI DRMGLPLLTE
110 120 130 140 150
GKEKAVRPAP VEPATPSEPP QNANPITKTR LIDVPVRSGQ RIYAPQCDLI
160 170 180 190 200
VTSHVSAGAE LIADGNIHVY GMMRGRALAG ASGDREAQIF CTHLTAELVS
210 220 230
IAGVYWLSDK IPAEFYGKAA RLRLADNALT VQPLN
Length:235
Mass (Da):25,246
Last modified:October 11, 2004 - v1
Checksum:iFF4165927F34056A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006468 Genomic DNA Translation: AAL20729.1
RefSeqiNP_460770.1, NC_003197.2
WP_000072527.1, NC_003197.2

Genome annotation databases

EnsemblBacteriaiAAL20729; AAL20729; STM1814
GeneIDi1253333
KEGGistm:STM1814
PATRICifig|99287.12.peg.1914

Similar proteinsi

Entry informationi

Entry nameiMINC_SALTY
AccessioniPrimary (citable) accession number: P65359
Secondary accession number(s): Q8XEJ9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: April 25, 2018
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

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