P65301 (LPPK_MYCBO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative lipoprotein LppK

Gene names

Name:	lppK
Ordered Locus Names:	Mb2140

Organism

Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) [Complete proteome] [HAMAP]

Taxonomic identifier

233413 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex › Mycobacterium bovis

Protein attributes

Sequence length	189 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Subcellular location	Cell membrane; Lipid-anchor Potential.
Sequence similarities	Belongs to the MTB12 family.

Ontologies

Keywords
Cellular component	Cell membrane Membrane
Domain	Signal
PTM	Lipoprotein Palmitate
Technical term	Complete proteome
Gene Ontology (GO)
Cellular_component	plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 22	22	Potential
	Chain	23 – 189	167	Putative lipoprotein LppK		PRO_0000018109
Amino acid modifications
	Lipidation	23	1	N-palmitoyl cysteine By similarity
	Lipidation	23	1	S-diacylglycerol cysteine By similarity

Sequences

	Sequence		Length	Mass (Da)
	P65301 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: FBF63A33BF83CB77	FASTA	189	19,728
	10 20 30 40 50 60 MRRNIRVTLG AATIVAALGL SGCSHPEFKR SSPPAPSLPP VTSSPLEAAP ITPLPAPEAL 70 80 90 100 110 120 IDVLSRLADP AVPGTNKVQL IEGATPENAA ALDRFTTALR DGSYLPMTFA ANDIAWSDNK 130 140 150 160 170 180 PSDVMATVVV TTAHPDNREF TFPMEFVSFK GGWQLSRQTA EMLLAMGNSP DSTPSATSPA PAPSPTPPG

References

[1]

"The complete genome sequence of Mycobacterium bovis." Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M., Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B., Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J. , Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G. Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-935 / AF2122/97.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX248341 Genomic DNA. Translation: CAD96993.1.
RefSeq	NP_855789.1. NC_002945.3.
3D structure databases
ProteinModelPortal	P65301.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAD96993; CAD96993; Mb2140.
GeneID	1091172.
KEGG	mbo:Mb2140.
PATRIC	18006412. VBIMycBov88188_2353.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	NOG12457.
HOGENOM	HOG000047847.
OMA	TFPMEFT.
ProtClustDB	CLSK791638.
Family and domain databases
InterPro	IPR020235. LMW_antigen_MTB12. [Graphical view]
ProDom	PD033474. LMW_antigen_MTB12. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS51257. PROKAR_LIPOPROTEIN. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

LPPK_MYCBO

Accession

Primary (citable) accession number: P65301
Secondary accession number(s): O33251

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 11, 2004
Last sequence update:	October 11, 2004
Last modified:	May 1, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program