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Reviewed, UniProtKB/Swiss-Prot P65289 (LIP1_STAAN)

Last modified February 9, 2010. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Lipase 1
    EC=3.1.1.3
Alternative name(s):
    Glycerol ester hydrolase 1
Gene names
Name: lip1
Ordered Locus Names: SA2463
OrganismStaphylococcus aureus (strain N315) [Complete proteome] [HAMAP]
Taxonomic identifier158879 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Staphylococcus

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Protein attributes

Sequence length680 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology.

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General annotation (Comments)

Catalytic activity

Triacylglycerol + H2O = diacylglycerol + a carboxylate.

Subcellular location

Secreted By similarity.

Sequence similarities

Belongs to the AB hydrolase superfamily. Lipase family.

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Ontologies

Keywords
   Biological processLipid degradation
   Cellular componentSecreted
   DomainSignal
   Molecular functionHydrolase
   PTMZymogen
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processlipid catabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

membrane

Inferred from electronic annotation. Source: InterPro

   Molecular functiontriglyceride lipase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 3434 Potential
Propeptide35 – 290256 By similarity
PRO_0000017750
Chain291 – 680390Lipase 1
PRO_0000017751

Sites

Active site4081Charge relay system By similarity
Active site6391Charge relay system By similarity

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Sequences

Sequence LengthMass (Da)Tools
P65289-1 [UniParc].

Last modified December 20, 2005. Version 2.
Checksum: 9F670E795C08C61F

FASTA68076,531
        10         20         30         40         50         60 
MKSQNKYSIR KFSVGASSIL IATLLFLSGG QAQAAEKQVN MGNSQEDTVT AQSIGDQQTR 

        70         80         90        100        110        120 
ENANYQRENG VDEQQHTENL TKNLHNDKTI SEENHRKTDD LNKDQLKDDK NSSLNNKNIQ 

       130        140        150        160        170        180 
RDTTKNNNAN PSDVNQGLEQ AINDGKQSKV ASQQQSKEVD NSQDSNANNN LPSQSLTKEA 

       190        200        210        220        230        240 
PSLNKSDQTS QREIVNETEI EKVQPQQNNQ ANDKITNHNF NNEQEVKPQK DEKTLSVSDL 

       250        260        270        280        290        300 
KNNQKSPVEP TKDNDKKNGL NLLKSSAVAT LPNKGTKELT AKAKDDQTNK VAKQGQYKNQ 

       310        320        330        340        350        360 
DPIVLVHGFN GFTDDINPSV LAHYWGGNKM NIRQDLEENG YKAYEASISA FGSNYDRAVE 

       370        380        390        400        410        420 
LYYYIKGGRV DYGAAHAAKY GHERYGKTYE GIYKDWKPGQ KVHLVGHSMG GQTIRQLEEL 

       430        440        450        460        470        480 
LRNGNREEIE YQKKHGGEIS PLFKGNNDNM ISSITTLGTP HNGTHASDLA GNEALVRQIV 

       490        500        510        520        530        540 
FDIGKMFGNK NSRVDFGLAQ WGLKQKPNES YIDYVKRVKQ SNLWKSKDNG FYDLTREGAT 

       550        560        570        580        590        600 
DLNRKTSLNP NIVYKTYTGE ATHKALNSDR QKADLNMFFP FVITGNLIGK ATEKEWREND 

       610        620        630        640        650        660 
GLVSVISSQH PFNQAYTNAT DKIQKGIWQV TPTKHDWDHV DFVGQDSSDT VRTREELQDF 

       670        680 
WHHLADDLVK TEKVTDTKQA

« Hide

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000018 Genomic DNA. Translation: BAB43769.1. Different initiation.
PIRG90075.
RefSeqNP_375790.1.

3D structure databases

SMRP65289. Positions 297-677.
ModBaseSearch...

Protein-protein interaction databases

STRINGP65289.

Genome annotation databases

GeneID1125393.
GenomeReviewsGene locus SA2463 in contig BA000018_GR.
KEGGsau:SA2463.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1075.
HOGENOMHBG694146.
OMAYTGESTH.

Enzyme and pathway databases

BioCycSAUR158879:SA2463-MONOMER.

Family and domain databases

InterProIPR005877. Gpos_YSIRK.
[Graphical view]
PfamPF04650. YSIRK_signal. 1 hit.
[Graphical view]
TIGRFAMsTIGR01168. YSIRK_signal. 1 hit.
PROSITEPS00120. LIPASE_SER. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameLIP1_STAAN
AccessionPrimary (citable) accession number: P65289
Secondary accession number(s): Q99QX0
Entry history
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: December 20, 2005
Last modified: February 9, 2010
This is version 39 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents