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P65252

- LACA_STAAW

UniProt

P65252 - LACA_STAAW

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Protein

Galactose-6-phosphate isomerase subunit LacA

Gene

lacA

Organism
Staphylococcus aureus (strain MW2)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-galactose 6-phosphate = D-tagatose 6-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. galactose-6-phosphate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. galactose catabolic process Source: UniProtKB-UniPathway
  2. lactose catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Lactose metabolism

Enzyme and pathway databases

BioCyciSAUR196620:GJ9Z-2199-MONOMER.
UniPathwayiUPA00702; UER00714.

Names & Taxonomyi

Protein namesi
Recommended name:
Galactose-6-phosphate isomerase subunit LacAUniRule annotation (EC:5.3.1.26UniRule annotation)
Gene namesi
Name:lacAUniRule annotation
Ordered Locus Names:MW2121
OrganismiStaphylococcus aureus (strain MW2)
Taxonomic identifieri196620 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000000418: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 142142Galactose-6-phosphate isomerase subunit LacAPRO_0000208110Add
BLAST

Interactioni

Subunit structurei

Heteromultimeric protein consisting of LacA and LacB.UniRule annotation

Protein-protein interaction databases

STRINGi196620.MW2121.

Structurei

3D structure databases

ProteinModelPortaliP65252.
SMRiP65252. Positions 1-141.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the LacAB/RpiB family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0698.
HOGENOMiHOG000226301.
KOiK01819.
OMAiHEVQKND.
OrthoDBiEOG6X9MQG.

Family and domain databases

Gene3Di3.40.1400.10. 1 hit.
HAMAPiMF_01555. LacA.
InterProiIPR004783. LacA.
IPR003500. RpiB_LacA_LacB.
[Graphical view]
PANTHERiPTHR30345. PTHR30345. 1 hit.
PfamiPF02502. LacAB_rpiB. 1 hit.
[Graphical view]
PIRSFiPIRSF005384. RpiB_LacA_B. 1 hit.
SUPFAMiSSF89623. SSF89623. 1 hit.
TIGRFAMsiTIGR01118. lacA. 1 hit.
TIGR00689. rpiB_lacA_lacB. 1 hit.

Sequencei

Sequence statusi: Complete.

P65252-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAIIIGSDEA GKRLKEVIKS YLLDNKYDVV DVTEGQEVDF VDATLAVAKD
60 70 80 90 100
VQSQEGNLGI VIDAFGAGSF MVATKIKGMI AAEVSDERSG YMTRGHNNSR
110 120 130 140
MITMGSEIVG DTLAKNVVKG FVEGKYDGGR HQIRVDMLNK MC
Length:142
Mass (Da):15,395
Last modified:October 11, 2004 - v1
Checksum:iA52C4A7DBF30BE19
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000033 Genomic DNA. Translation: BAB95986.1.
RefSeqiNP_646938.1. NC_003923.1.

Genome annotation databases

EnsemblBacteriaiBAB95986; BAB95986; BAB95986.
GeneIDi1004239.
KEGGisam:MW2121.
PATRICi19570968. VBIStaAur44266_2193.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000033 Genomic DNA. Translation: BAB95986.1 .
RefSeqi NP_646938.1. NC_003923.1.

3D structure databases

ProteinModelPortali P65252.
SMRi P65252. Positions 1-141.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 196620.MW2121.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAB95986 ; BAB95986 ; BAB95986 .
GeneIDi 1004239.
KEGGi sam:MW2121.
PATRICi 19570968. VBIStaAur44266_2193.

Phylogenomic databases

eggNOGi COG0698.
HOGENOMi HOG000226301.
KOi K01819.
OMAi HEVQKND.
OrthoDBi EOG6X9MQG.

Enzyme and pathway databases

UniPathwayi UPA00702 ; UER00714 .
BioCyci SAUR196620:GJ9Z-2199-MONOMER.

Family and domain databases

Gene3Di 3.40.1400.10. 1 hit.
HAMAPi MF_01555. LacA.
InterProi IPR004783. LacA.
IPR003500. RpiB_LacA_LacB.
[Graphical view ]
PANTHERi PTHR30345. PTHR30345. 1 hit.
Pfami PF02502. LacAB_rpiB. 1 hit.
[Graphical view ]
PIRSFi PIRSF005384. RpiB_LacA_B. 1 hit.
SUPFAMi SSF89623. SSF89623. 1 hit.
TIGRFAMsi TIGR01118. lacA. 1 hit.
TIGR00689. rpiB_lacA_lacB. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MW2.

Entry informationi

Entry nameiLACA_STAAW
AccessioniPrimary (citable) accession number: P65252
Secondary accession number(s): Q99S74
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: October 1, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3