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P65251 (LACA_STAAN) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Galactose-6-phosphate isomerase subunit LacA

EC=5.3.1.26
Gene names
Name:lacA
Ordered Locus Names:SA1997
OrganismStaphylococcus aureus (strain N315) [Complete proteome] [HAMAP]
Taxonomic identifier158879 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesStaphylococcus

Protein attributes

Sequence length142 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-galactose 6-phosphate = D-tagatose 6-phosphate. HAMAP-Rule MF_01555

Pathway

Carbohydrate metabolism; D-galactose 6-phosphate degradation; D-tagatose 6-phosphate from D-galactose 6-phosphate: step 1/1. HAMAP-Rule MF_01555

Subunit structure

Heteromultimeric protein consisting of LacA and LacB By similarity.

Sequence similarities

Belongs to the LacAB/RpiB family.

Ontologies

Keywords
   Biological processLactose metabolism
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgalactose catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

lactose catabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functiongalactose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 142142Galactose-6-phosphate isomerase subunit LacA HAMAP-Rule MF_01555
PRO_0000208111

Sequences

Sequence LengthMass (Da)Tools
P65251 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: A52C4A7DBF30BE19

FASTA14215,395
        10         20         30         40         50         60 
MAIIIGSDEA GKRLKEVIKS YLLDNKYDVV DVTEGQEVDF VDATLAVAKD VQSQEGNLGI 

        70         80         90        100        110        120 
VIDAFGAGSF MVATKIKGMI AAEVSDERSG YMTRGHNNSR MITMGSEIVG DTLAKNVVKG 

       130        140 
FVEGKYDGGR HQIRVDMLNK MC 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000018 Genomic DNA. Translation: BAB43287.1.
PIRF90015.
RefSeqNP_375308.1. NC_002745.2.

3D structure databases

ProteinModelPortalP65251.
SMRP65251. Positions 1-141.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING158879.SA1997.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB43287; BAB43287; BAB43287.
GeneID1124913.
KEGGsau:SA1997.
PATRIC19576480. VBIStaAur116463_2158.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0698.
HOGENOMHOG000226301.
KOK01819.
OMAHEVQKND.
OrthoDBEOG6X9MQG.
ProtClustDBPRK08621.

Enzyme and pathway databases

BioCycSAUR158879:GJCB-2145-MONOMER.
UniPathwayUPA00702; UER00714.

Family and domain databases

Gene3D3.40.1400.10. 1 hit.
HAMAPMF_01555. LacA.
InterProIPR004783. Gal-6-P_isomerase_su_LacA.
IPR003500. RpiB_LacA_LacB.
[Graphical view]
PANTHERPTHR30345. PTHR30345. 1 hit.
PfamPF02502. LacAB_rpiB. 1 hit.
[Graphical view]
PIRSFPIRSF005384. RpiB_LacA_B. 1 hit.
SUPFAMSSF89623. SSF89623. 1 hit.
TIGRFAMsTIGR01118. lacA. 1 hit.
TIGR00689. rpiB_lacA_lacB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameLACA_STAAN
AccessionPrimary (citable) accession number: P65251
Secondary accession number(s): Q99S74
Entry history
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: February 19, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways