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P65251

- LACA_STAAN

UniProt

P65251 - LACA_STAAN

Protein

Galactose-6-phosphate isomerase subunit LacA

Gene

lacA

Organism
Staphylococcus aureus (strain N315)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 1 (11 Oct 2004)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-galactose 6-phosphate = D-tagatose 6-phosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. galactose-6-phosphate isomerase activity Source: UniProtKB-EC

    GO - Biological processi

    1. galactose catabolic process Source: UniProtKB-UniPathway
    2. lactose catabolic process Source: InterPro

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Lactose metabolism

    Enzyme and pathway databases

    BioCyciSAUR158879:GJCB-2145-MONOMER.
    UniPathwayiUPA00702; UER00714.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Galactose-6-phosphate isomerase subunit LacAUniRule annotation (EC:5.3.1.26UniRule annotation)
    Gene namesi
    Name:lacAUniRule annotation
    Ordered Locus Names:SA1997
    OrganismiStaphylococcus aureus (strain N315)
    Taxonomic identifieri158879 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
    ProteomesiUP000000751: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 142142Galactose-6-phosphate isomerase subunit LacAPRO_0000208111Add
    BLAST

    Interactioni

    Subunit structurei

    Heteromultimeric protein consisting of LacA and LacB.UniRule annotation

    Protein-protein interaction databases

    STRINGi158879.SA1997.

    Structurei

    3D structure databases

    ProteinModelPortaliP65251.
    SMRiP65251. Positions 1-141.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the LacAB/RpiB family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0698.
    HOGENOMiHOG000226301.
    KOiK01819.
    OMAiHEVQKND.
    OrthoDBiEOG6X9MQG.

    Family and domain databases

    Gene3Di3.40.1400.10. 1 hit.
    HAMAPiMF_01555. LacA.
    InterProiIPR004783. LacA.
    IPR003500. RpiB_LacA_LacB.
    [Graphical view]
    PANTHERiPTHR30345. PTHR30345. 1 hit.
    PfamiPF02502. LacAB_rpiB. 1 hit.
    [Graphical view]
    PIRSFiPIRSF005384. RpiB_LacA_B. 1 hit.
    SUPFAMiSSF89623. SSF89623. 1 hit.
    TIGRFAMsiTIGR01118. lacA. 1 hit.
    TIGR00689. rpiB_lacA_lacB. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P65251-1 [UniParc]FASTAAdd to Basket

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    MAIIIGSDEA GKRLKEVIKS YLLDNKYDVV DVTEGQEVDF VDATLAVAKD    50
    VQSQEGNLGI VIDAFGAGSF MVATKIKGMI AAEVSDERSG YMTRGHNNSR 100
    MITMGSEIVG DTLAKNVVKG FVEGKYDGGR HQIRVDMLNK MC 142
    Length:142
    Mass (Da):15,395
    Last modified:October 11, 2004 - v1
    Checksum:iA52C4A7DBF30BE19
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000018 Genomic DNA. Translation: BAB43287.1.
    PIRiF90015.
    RefSeqiNP_375308.1. NC_002745.2.

    Genome annotation databases

    EnsemblBacteriaiBAB43287; BAB43287; BAB43287.
    GeneIDi1124913.
    KEGGisau:SA1997.
    PATRICi19576480. VBIStaAur116463_2158.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000018 Genomic DNA. Translation: BAB43287.1 .
    PIRi F90015.
    RefSeqi NP_375308.1. NC_002745.2.

    3D structure databases

    ProteinModelPortali P65251.
    SMRi P65251. Positions 1-141.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 158879.SA1997.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAB43287 ; BAB43287 ; BAB43287 .
    GeneIDi 1124913.
    KEGGi sau:SA1997.
    PATRICi 19576480. VBIStaAur116463_2158.

    Phylogenomic databases

    eggNOGi COG0698.
    HOGENOMi HOG000226301.
    KOi K01819.
    OMAi HEVQKND.
    OrthoDBi EOG6X9MQG.

    Enzyme and pathway databases

    UniPathwayi UPA00702 ; UER00714 .
    BioCyci SAUR158879:GJCB-2145-MONOMER.

    Family and domain databases

    Gene3Di 3.40.1400.10. 1 hit.
    HAMAPi MF_01555. LacA.
    InterProi IPR004783. LacA.
    IPR003500. RpiB_LacA_LacB.
    [Graphical view ]
    PANTHERi PTHR30345. PTHR30345. 1 hit.
    Pfami PF02502. LacAB_rpiB. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF005384. RpiB_LacA_B. 1 hit.
    SUPFAMi SSF89623. SSF89623. 1 hit.
    TIGRFAMsi TIGR01118. lacA. 1 hit.
    TIGR00689. rpiB_lacA_lacB. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: N315.

    Entry informationi

    Entry nameiLACA_STAAN
    AccessioniPrimary (citable) accession number: P65251
    Secondary accession number(s): Q99S74
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 11, 2004
    Last sequence update: October 11, 2004
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3