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Protein

Protein-arginine kinase

Gene

mcsB

Organism
Staphylococcus aureus (strain Mu50 / ATCC 700699)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the specific phosphorylation of arginine residues in proteins.UniRule annotation

Catalytic activityi

ATP + a [protein]-L-arginine = ADP + a [protein]-N(omega)-phospho-L-arginine.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei82ATPUniRule annotation1
Binding sitei115ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi24 – 28ATPUniRule annotation5
Nucleotide bindingi166 – 170ATPUniRule annotation5
Nucleotide bindingi197 – 202ATPUniRule annotation6

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Protein-arginine kinaseUniRule annotation (EC:2.7.14.1UniRule annotation)
Gene namesi
Name:mcsBUniRule annotation
Ordered Locus Names:SAV0524
OrganismiStaphylococcus aureus (strain Mu50 / ATCC 700699)
Taxonomic identifieri158878 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000002481 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002120291 – 335Protein-arginine kinaseAdd BLAST335

Proteomic databases

PaxDbiP65205

2D gel databases

World-2DPAGEi0002:P65205

Interactioni

Protein-protein interaction databases

STRINGi158878.SAV0524

Structurei

3D structure databases

ProteinModelPortaliP65205
SMRiP65205
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini21 – 244Phosphagen kinase C-terminalUniRule annotationAdd BLAST224

Sequence similaritiesi

Belongs to the ATP:guanido phosphotransferase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG41066A3 Bacteria
COG3869 LUCA
HOGENOMiHOG000082112
KOiK19405
OMAiACPTNVG
PhylomeDBiP65205

Family and domain databases

CDDicd07930 bacterial_phosphagen_kinase, 1 hit
HAMAPiMF_00602 Prot_Arg_kinase, 1 hit
InterProiView protein in InterPro
IPR023660 Arg_Kinase
IPR000749 ATP-guanido_PTrfase
IPR022415 ATP-guanido_PTrfase_AS
IPR022414 ATP-guanido_PTrfase_cat
IPR014746 Gln_synth/guanido_kin_cat_dom
PANTHERiPTHR11547 PTHR11547, 1 hit
PfamiView protein in Pfam
PF00217 ATP-gua_Ptrans, 1 hit
SUPFAMiSSF55931 SSF55931, 1 hit
PROSITEiView protein in PROSITE
PS00112 PHOSPHAGEN_KINASE, 1 hit
PS51510 PHOSPHAGEN_KINASE_C, 1 hit

Sequencei

Sequence statusi: Complete.

P65205-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTHNIHDNIS QWMKSNEETP IVMSSRIRLA RNLENHVHPL MYATENDGFR
60 70 80 90 100
VINEVQDALP NFELMRLDQM DQQSKMKMVA KHLISPELIK QPAAAVLVND
110 120 130 140 150
DESLSVMINE EDHIRIQAMG TDTTLQALYN QASSIDDELD RSLDISYDEQ
160 170 180 190 200
LGYLTTCPTN IGTGMRASVM LHLPGLSIMK RMTRIAQTIN RFGYTIRGIY
210 220 230 240 250
GEGSQVYGHT YQVSNQLTLG KSELEIIETL TEVVNQIIHD EKQIRQKLDT
260 270 280 290 300
YNQLETQDRV FRSLGILQNC RMITMEEASY RLSEVKLGID LNYIELQNFK
310 320 330
FNELMVAIQS PFLLDEEDDK SVKEKRADIL REHIK
Length:335
Mass (Da):38,596
Last modified:October 11, 2004 - v1
Checksum:iE1AA8D8B9BA0D4BB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000017 Genomic DNA Translation: BAB56686.1
RefSeqiWP_000149502.1, NC_002758.2

Genome annotation databases

EnsemblBacteriaiBAB56686; BAB56686; SAV0524
KEGGisav:SAV0524

Similar proteinsi

Entry informationi

Entry nameiMCSB_STAAM
AccessioniPrimary (citable) accession number: P65205
Secondary accession number(s): Q99W79
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: April 25, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health