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P65081 (Y3413_MYCTU) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Uncharacterized protein Rv3413c/MT3522
Gene names
Ordered Locus Names:Rv3413c, MT3522
ORF Names:MTCY78.16
OrganismMycobacterium tuberculosis [Reference proteome] [HAMAP]
Taxonomic identifier1773 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length299 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Cell membrane; Single-pass membrane protein Potential.

Induction

Positively regulated by alternative sigma factor SigD. Ref.3

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 299299Uncharacterized protein Rv3413c/MT3522
PRO_0000104133

Regions

Transmembrane86 – 10621Helical; Potential
Compositional bias201 – 29797Pro-rich

Secondary structure

1 ..... 299
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P65081 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: CFCEDFE38C8E0B5C

FASTA29931,248
        10         20         30         40         50         60 
MREFGNPLGD RPPLDELART DLLLDALAER EEVDFADPRD DALAALLGQW RDDLRWPPAS 

        70         80         90        100        110        120 
ALVSQDEAVA ALRAGVAQRR RARRSLAAVG SVAAALLVLS GFGAVVADAR PGDLLYGLHA 

       130        140        150        160        170        180 
MMFNRSRVSD DQIVLSAKAN LAKVEQMIAQ GQWAEAQDEL AEVSSTVQAV TDGSRRQDLI 

       190        200        210        220        230        240 
NEVNLLNTKV ETRDPNATLR PGSPSNPAAP GSVGNSWTPL APVVEPPTPP TPASAAEPSM 

       250        260        270        280        290 
SAGVSESPMP NSTSTVAASP STPSSKPEPG SIDPSLEPAD EATNPAGQPA PETPVSPTH

« Hide

References

« Hide 'large scale' references
[1]"Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence."
Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E., Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K. expand/collapse author list , Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J., Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S., Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S., Barrell B.G.
Nature 393:537-544(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 25618 / H37Rv.
[2]"Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains."
Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O., Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K., Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L., Delcher A., Utterback T.R. expand/collapse author list , Weidman J.F., Khouri H.M., Gill J., Mikula A., Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.
J. Bacteriol. 184:5479-5490(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CDC 1551 / Oshkosh.
[3]"Transcription regulation by the Mycobacterium tuberculosis alternative sigma factor SigD and its role in virulence."
Raman S., Hazra R., Dascher C.C., Husson R.N.
J. Bacteriol. 186:6605-6616(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: INDUCTION.
Strain: ATCC 25618 / H37Rv.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BX842583 Genomic DNA. Translation: CAB01010.1.
AE000516 Genomic DNA. Translation: AAK47860.1.
AL123456 Genomic DNA. Translation: CCP46235.1.
PIRB70737.
RefSeqNP_217930.1. NC_000962.3.
NP_338046.1. NC_002755.2.
YP_006516899.1. NC_018143.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3VEPX-ray2.50C/G/J/X1-80[»]
ProteinModelPortalP65081.
ModBaseSearch...

Protein-protein interaction databases

STRING83332.Rv3413c.

Proteomic databases

PRIDEP65081.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAK47860; AAK47860; MT3522.
GeneID13317017.
887925.
923088.
KEGGmtc:MT3522.
mtu:Rv3413c.
mtv:RVBD_3413c.
PATRIC18129481. VBIMycTub22151_3836.

Organism-specific databases

TubercuListRv3413c.

Phylogenomic databases

eggNOGNOG12793.
HOGENOMHOG000043964.
OMADEVARTD.
ProtClustDBCLSK792478.

Family and domain databases

ProtoNetSearch...

Entry information

Entry nameY3413_MYCTU
AccessionPrimary (citable) accession number: P65081
Secondary accession number(s): L0TFJ3, Q50713
Entry history
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: May 1, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Mycobacterium tuberculosis strains ATCC 25618 / H37Rv and CDC 1551 / Oshkosh

Mycobacterium tuberculosis strains ATCC 25618 / H37Rv and CDC 1551 / Oshkosh: entries and gene names

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents