SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P64804

- PDUO_MYCBO

UniProt

P64804 - PDUO_MYCBO

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Cob(I)yrinic acid a,c-diamide adenosyltransferase
Gene
Mb1347c
Organism
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + cob(I)yrinic acid a,c-diamide = triphosphate + adenosylcob(III)yrinic acid a,c-diamide.
ATP + cobinamide = triphosphate + adenosylcobinamide.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei28 – 281ATP By similarity
Binding sitei163 – 1631ATP By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi10 – 189ATP By similarity
Nucleotide bindingi137 – 1426ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. cob(I)yrinic acid a,c-diamide adenosyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. cobalamin biosynthetic process Source: UniProtKB-UniPathway
  2. porphyrin-containing compound biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Cobalamin biosynthesis, Porphyrin biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00148; UER00233.

Names & Taxonomyi

Protein namesi
Recommended name:
Cob(I)yrinic acid a,c-diamide adenosyltransferase (EC:2.5.1.17)
Alternative name(s):
Cob(I)alamin adenosyltransferase
Gene namesi
Ordered Locus Names:Mb1347c
OrganismiMycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Taxonomic identifieri233413 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
ProteomesiUP000001419: Chromosome

Subcellular locationi

Cytoplasm Reviewed prediction

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 193193Cob(I)yrinic acid a,c-diamide adenosyltransferase
PRO_0000103799Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi233413.Mb1347c.

Structurei

3D structure databases

ProteinModelPortaliP64804.
SMRiP64804. Positions 29-188.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG2096.
HOGENOMiHOG000291639.
OMAiDSFTNMK.
OrthoDBiEOG6SZ1P1.

Family and domain databases

Gene3Di1.20.1200.10. 1 hit.
InterProiIPR016030. AdoCbl_synth_CblAdoTrfase-like.
IPR029499. PduO-typ.
[Graphical view]
PfamiPF01923. Cob_adeno_trans. 1 hit.
[Graphical view]
ProDomiPD007457. AdoCbl_syn_CblAdoTrfase_PduO_N. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF89028. SSF89028. 1 hit.
TIGRFAMsiTIGR00636. PduO_Nterm. 1 hit.

Sequencei

Sequence statusi: Complete.

P64804-1 [UniParc]FASTAAdd to Basket

« Hide

MAVHLTRIYT RTGDDGTTGL SDMSRVAKTD ARLVAYADCD EANAAIGAAL    50
ALGHPDTQIT DVLRQIQNDL FDAGADLSTP IVENPKHPPL RIAQSYIDRL 100
EGWCDAYNAG LPALKSFVLP GGSPLSALLH VARTVVRRAE RSAWAAVDAH 150
PEGVSVLPAK YLNRLSDLLF ILSRVANPDG DVLWRPGGDR TAS 193
Length:193
Mass (Da):20,694
Last modified:October 11, 2004 - v1
Checksum:i2FB302A9F5A5208B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX248333 Genomic DNA. Translation: CDO42594.1.
RefSeqiNP_855001.1. NC_002945.3.

Genome annotation databases

EnsemblBacteriaiCAD94208; CAD94208; Mb1347c.
GeneIDi1090637.
KEGGimbo:Mb1347c.
PATRICi18004649. VBIMycBov88188_1476.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX248333 Genomic DNA. Translation: CDO42594.1 .
RefSeqi NP_855001.1. NC_002945.3.

3D structure databases

ProteinModelPortali P64804.
SMRi P64804. Positions 29-188.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 233413.Mb1347c.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAD94208 ; CAD94208 ; Mb1347c .
GeneIDi 1090637.
KEGGi mbo:Mb1347c.
PATRICi 18004649. VBIMycBov88188_1476.

Phylogenomic databases

eggNOGi COG2096.
HOGENOMi HOG000291639.
OMAi DSFTNMK.
OrthoDBi EOG6SZ1P1.

Enzyme and pathway databases

UniPathwayi UPA00148 ; UER00233 .

Family and domain databases

Gene3Di 1.20.1200.10. 1 hit.
InterProi IPR016030. AdoCbl_synth_CblAdoTrfase-like.
IPR029499. PduO-typ.
[Graphical view ]
Pfami PF01923. Cob_adeno_trans. 1 hit.
[Graphical view ]
ProDomi PD007457. AdoCbl_syn_CblAdoTrfase_PduO_N. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
SUPFAMi SSF89028. SSF89028. 1 hit.
TIGRFAMsi TIGR00636. PduO_Nterm. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-935 / AF2122/97.

Entry informationi

Entry nameiPDUO_MYCBO
AccessioniPrimary (citable) accession number: P64804
Secondary accession number(s): Q10622, X2BHJ1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: June 11, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi