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Protein

DNA utilization protein HofN

Gene

hofN

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein predictedi

Functioni

Required for the use of extracellular DNA as a nutrient.1 Publication

GO - Biological processi

  • carbon utilization Source: EcoCyc
  • DNA catabolic process Source: EcoCyc

Enzyme and pathway databases

BioCyciEcoCyc:G7738-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
DNA utilization protein HofN
Gene namesi
Name:hofN
Synonyms:yrfC
Ordered Locus Names:b3394, JW3357
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12924 hofN

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei19 – 39HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

Pathology & Biotechi

Disruption phenotypei

Mutants are unable to use DNA as a sole carbon and energy source and show decreased competitive fitness when cocultured with wild-type cells.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001695391 – 179DNA utilization protein HofNAdd BLAST179

Proteomic databases

PaxDbiP64634
PRIDEiP64634

Interactioni

Protein-protein interaction databases

BioGridi42630397 interactors.
STRINGi316385.ECDH10B_3569

Structurei

3D structure databases

ProteinModelPortaliP64634
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG41065NF Bacteria
COG3166 LUCA
HOGENOMiHOG000125532
KOiK12289
OMAiNRTGATQ

Family and domain databases

InterProiView protein in InterPro
IPR007813 PilN
PfamiView protein in Pfam
PF05137 PilN, 1 hit

Sequencei

Sequence statusi: Complete.

P64634-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNPPINFLPW RQQRRTAFLR FWLLMFVAPL LLAVGITLIL RLTGSAEARI
60 70 80 90 100
DAVLLQAEQQ LARSLQITKP RLLEQQQLRE QRSQRQRQRQ FTRDWQSALE
110 120 130 140 150
ALAALLPEHA WLTTISWQQG TLEIKGLTTS ITALNALETS LRQDASFHLN
160 170
QRGATQQDAQ GRWQFEYQLT RKVSDEHVL
Length:179
Mass (Da):20,796
Last modified:October 11, 2004 - v1
Checksum:i2A7D86A4B36B10C8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA Translation: AAA58191.1
U00096 Genomic DNA Translation: AAC76419.1
AP009048 Genomic DNA Translation: BAE77897.1
PIRiE65134
RefSeqiNP_417853.1, NC_000913.3
WP_001069315.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC76419; AAC76419; b3394
BAE77897; BAE77897; BAE77897
GeneIDi947898
KEGGiecj:JW3357
eco:b3394
PATRICifig|1411691.4.peg.3336

Similar proteinsi

Entry informationi

Entry nameiHOFN_ECOLI
AccessioniPrimary (citable) accession number: P64634
Secondary accession number(s): P45752, Q2M759
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: March 28, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome