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Protein

Transcriptional regulator YqjI

Gene

yqjI

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Represses the expression of YqjH which is involved in iron homeostasis under excess nickel conditions. Also represses its own expression.1 Publication

Enzyme regulationi

Divalent metals such as nickel and iron have a similar negative effect on YqjI DNA-binding activity.1 Publication

GO - Molecular functioni

  • DNA binding Source: EcoCyc
  • DNA binding transcription factor activity Source: EcoCyc

GO - Biological processi

  • cellular response to DNA damage stimulus Source: EcoliWiki
  • negative regulation of transcription, DNA-templated Source: EcoCyc
  • positive regulation of transcription, DNA-templated Source: EcoCyc
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Molecular functionDNA-binding, Repressor
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

BioCyciEcoCyc:G7594-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional regulator YqjI
Gene namesi
Name:yqjI
Ordered Locus Names:b3071, JW3042
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12954 yqjI

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: EcoCyc

Pathology & Biotechi

Disruption phenotypei

Disruption leads to a 40-fold increase in yqjH basal expression.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001694381 – 207Transcriptional regulator YqjIAdd BLAST207

Proteomic databases

PaxDbiP64588
PRIDEiP64588

Expressioni

Inductioni

Autorepressed.1 Publication

Interactioni

Subunit structurei

Oligomer (probable predominant form) and monomer.1 Publication

Protein-protein interaction databases

BioGridi4259594, 11 interactors
DIPiDIP-48127N
IntActiP64588, 31 interactors
STRINGi316385.ECDH10B_3246

Structurei

3D structure databases

ProteinModelPortaliP64588
SMRiP64588
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4105NTW Bacteria
COG1695 LUCA
HOGENOMiHOG000221100
InParanoidiP64588
OMAiNASHGYE
PhylomeDBiP64588

Family and domain databases

Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR005149 Tscrpt_reg_PadR_N
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF03551 PadR, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit

Sequencei

Sequence statusi: Complete.

P64588-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSHHHEGCCK HEGQPRHEGC CKGEKSEHEH CGHGHQHEHG QCCGGRHGRG
60 70 80 90 100
GGRRQRFFGH GELRLVILDI LSRDDSHGYE LIKAIENLTQ GNYTPSPGVI
110 120 130 140 150
YPTLDFLQEQ SLITIREEEG GKKQIALTEQ GAQWLEENRE QVEMIEERIK
160 170 180 190 200
ARCVGAALRQ NPQMKRALDN FKAVLDLRVN QSDISDAQIK KIIAVIDRAA

FDITQLD
Length:207
Mass (Da):23,401
Last modified:October 11, 2004 - v1
Checksum:iDD3D108D83E087F7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U28379 Genomic DNA Translation: AAA89150.1
U00096 Genomic DNA Translation: AAC76106.1
AP009048 Genomic DNA Translation: BAE77121.1
PIRiD65095
RefSeqiNP_417542.1, NC_000913.3
WP_000018003.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC76106; AAC76106; b3071
BAE77121; BAE77121; BAE77121
GeneIDi947584
KEGGiecj:JW3042
eco:b3071
PATRICifig|1411691.4.peg.3659

Similar proteinsi

Entry informationi

Entry nameiYQJI_ECOLI
AccessioniPrimary (citable) accession number: P64588
Secondary accession number(s): Q2M9D5, Q46872
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: March 28, 2018
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

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