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Protein

Transcriptional repressor RcnR

Gene

rcnR

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Repressor of rcnA expression. Acts by binding specifically to the rcnA promoter in the absence of nickel and cobalt. In the presence of one of these metals, it has a weaker affinity for rcnA promoter.2 Publications

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Repressor

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciEcoCyc:G7137-MONOMER.
ECOL316407:JW2092-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional repressor RcnR
Gene namesi
Name:rcnR
Synonyms:yohL
Ordered Locus Names:b2105, JW2092
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG14070. rcnR.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001691431 – 90Transcriptional repressor RcnRAdd BLAST90

Proteomic databases

PaxDbiP64530.
PRIDEiP64530.

Interactioni

Protein-protein interaction databases

BioGridi4261164. 9 interactors.
IntActiP64530. 8 interactors.
STRINGi511145.b2105.

Structurei

3D structure databases

ProteinModelPortaliP64530.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FrmR/RcnR family.Curated

Phylogenomic databases

eggNOGiENOG41090EM. Bacteria.
COG1937. LUCA.
HOGENOMiHOG000023914.
InParanoidiP64530.
OMAiHLTECIA.
PhylomeDBiP64530.

Family and domain databases

InterProiIPR003735. Metal_Tscrpt_repr.
[Graphical view]
PfamiPF02583. Trns_repr_metal. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P64530-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSHTIRDKQK LKARASKIQG QVVALKKMLD EPHECAAVLQ QIAAIRGAVN
60 70 80 90
GLMREVIKGH LTEHIVHQGD ELKREEDLDV VLKVLDSYIK
Length:90
Mass (Da):10,134
Last modified:October 11, 2004 - v1
Checksum:iBEF3E5AE971AA2F6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75166.1.
AP009048 Genomic DNA. Translation: BAE76586.1.
PIRiH64977.
RefSeqiNP_416608.1. NC_000913.3.
WP_000019944.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75166; AAC75166; b2105.
BAE76586; BAE76586; BAE76586.
GeneIDi947114.
KEGGiecj:JW2092.
eco:b2105.
PATRICi32119543. VBIEscCol129921_2182.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75166.1.
AP009048 Genomic DNA. Translation: BAE76586.1.
PIRiH64977.
RefSeqiNP_416608.1. NC_000913.3.
WP_000019944.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP64530.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261164. 9 interactors.
IntActiP64530. 8 interactors.
STRINGi511145.b2105.

Proteomic databases

PaxDbiP64530.
PRIDEiP64530.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75166; AAC75166; b2105.
BAE76586; BAE76586; BAE76586.
GeneIDi947114.
KEGGiecj:JW2092.
eco:b2105.
PATRICi32119543. VBIEscCol129921_2182.

Organism-specific databases

EchoBASEiEB3823.
EcoGeneiEG14070. rcnR.

Phylogenomic databases

eggNOGiENOG41090EM. Bacteria.
COG1937. LUCA.
HOGENOMiHOG000023914.
InParanoidiP64530.
OMAiHLTECIA.
PhylomeDBiP64530.

Enzyme and pathway databases

BioCyciEcoCyc:G7137-MONOMER.
ECOL316407:JW2092-MONOMER.

Miscellaneous databases

PROiP64530.

Family and domain databases

InterProiIPR003735. Metal_Tscrpt_repr.
[Graphical view]
PfamiPF02583. Trns_repr_metal. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRCNR_ECOLI
AccessioniPrimary (citable) accession number: P64530
Secondary accession number(s): P76424, Q2MAX0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: November 2, 2016
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.