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Protein

Chaperone protein DnaK

Gene

dnaK

Organism
Staphylococcus aureus (strain MW2)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Acts as a chaperone.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
Biological processStress response
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein DnaKUniRule annotation
Alternative name(s):
HSP70UniRule annotation
Heat shock 70 kDa proteinUniRule annotation
Heat shock protein 70UniRule annotation
Gene namesi
Name:dnaKUniRule annotation
Ordered Locus Names:MW1532
OrganismiStaphylococcus aureus (strain MW2)
Taxonomic identifieri196620 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000000418 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000785411 – 610Chaperone protein DnaKAdd BLAST610

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei173Phosphothreonine; by autocatalysisUniRule annotation1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiP64408

Expressioni

Inductioni

By stress conditions e.g. heat shock.UniRule annotation

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliP64408
SMRiP64408
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 70 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000228137
KOiK04043
OMAiISIKRHM

Family and domain databases

Gene3Di1.20.1270.10, 1 hit
2.60.34.10, 1 hit
HAMAPiMF_00332 DnaK, 1 hit
InterProiView protein in InterPro
IPR012725 Chaperone_DnaK
IPR018181 Heat_shock_70_CS
IPR029048 HSP70_C_sf
IPR029047 HSP70_peptide-bd_sf
IPR013126 Hsp_70_fam
PANTHERiPTHR19375 PTHR19375, 1 hit
PfamiView protein in Pfam
PF00012 HSP70, 1 hit
PRINTSiPR00301 HEATSHOCK70
SUPFAMiSSF100920 SSF100920, 1 hit
SSF100934 SSF100934, 1 hit
TIGRFAMsiTIGR02350 prok_dnaK, 1 hit
PROSITEiView protein in PROSITE
PS00297 HSP70_1, 1 hit
PS00329 HSP70_2, 1 hit
PS01036 HSP70_3, 1 hit

Sequencei

Sequence statusi: Complete.

P64408-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKIIGIDLG TTNSCVTVLE GDEPKVIQNP EGSRTTPSVV AFKNGETQVG
60 70 80 90 100
EVAKRQAITN PNTVQSIKRH MGTDYKVDIE GKSYTPQEIS AMILQNLKNT
110 120 130 140 150
AESYLGEKVD KAVITVPAYF NDAERQATKD AGKIAGLEVE RIINEPTAAA
160 170 180 190 200
LAYGLDKTDK DEKVLVFDLG GGTFDVSILE LGDGVFEVLS TAGDNKLGGD
210 220 230 240 250
DFDQVIIDYL VAEFKKENGV DLSQDKMALQ RLKDAAEKAK KDLSGVSQTQ
260 270 280 290 300
ISLPFISAGE NGPLHLEVNL TRSKFEELSD SLIRRTMEPT RQAMKDAGLT
310 320 330 340 350
NSDIDEVILV GGSTRIPAVQ EAVKKEIGKE PNKGVNPDEV VAMGAAIQGG
360 370 380 390 400
VITGDVKDVV LLDVTPLSLG IEILGGRMNT LIERNTTIPT SKSQIYSTAV
410 420 430 440 450
DNQPSVDVHV LQGERPMAAD NKTLGRFQLT DIPPAERGKP QIEVTFDIDK
460 470 480 490 500
NGIVNVTAKD LGTNKEQRIT IQSSSSLSDE EIDRMVKDAE VNAEADKKRR
510 520 530 540 550
EEVDLRNEAD SLVFQVEKTL TDLGENIGEE DKKSAEEKKD ALKTALEGQD
560 570 580 590 600
IEDIKSKKEE LEKVIQELSA KVYEQAAQQQ QQAQGANAGQ NNDSTVEDAE
610
FKEVKDDDKK
Length:610
Mass (Da):66,361
Last modified:October 11, 2004 - v1
Checksum:iB71645C36D26AAED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000033 Genomic DNA Translation: BAB95397.1
RefSeqiWP_000034716.1, NC_003923.1

Genome annotation databases

EnsemblBacteriaiBAB95397; BAB95397; BAB95397
KEGGisam:MW1532

Similar proteinsi

Entry informationi

Entry nameiDNAK_STAAW
AccessioniPrimary (citable) accession number: P64408
Secondary accession number(s): Q99TR7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: March 28, 2018
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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