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P64275 (GREA_HELPY) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Transcription elongation factor GreA
Alternative name(s):
Transcript cleavage factor GreA
Gene names
Name:greA
Ordered Locus Names:HP_0866
OrganismHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) [Reference proteome] [HAMAP]
Taxonomic identifier85962 [NCBI]
Taxonomic lineageBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter

Protein attributes

Sequence length164 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides By similarity. HAMAP-Rule MF_00105

Sequence similarities

Belongs to the GreA/GreB family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 164164Transcription elongation factor GreA HAMAP-Rule MF_00105
PRO_0000176931

Sequences

Sequence LengthMass (Da)Tools
P64275 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: 439E43A5FD0965BE

FASTA16418,199
        10         20         30         40         50         60 
MNKEPMSMHG YNKICAELKQ LKEVERPNIV KEIDIARGHG DLKENAEYHA AKEKQRFIEA 

        70         80         90        100        110        120 
RIVDLSEIVA NAQVIDPSAL AHNKVSFGST IKILNLDNDK EFSYTIVGSV ESDPAKGLIS 

       130        140        150        160 
FGSPIAKSLI GKSKGDAVSI QLPNGESDFE ILDIYYKEIC FDEN 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE000511 Genomic DNA. Translation: AAD07908.1.
PIRB64628.
RefSeqNP_207660.1. NC_000915.1.
YP_006934780.1. NC_018939.1.

3D structure databases

ProteinModelPortalP64275.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING85962.HP0866.

Proteomic databases

PRIDEP64275.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAD07908; AAD07908; HP_0866.
GeneID899395.
KEGGheo:C694_04435.
hpy:HP0866.
PATRIC20593021. VBIHelPyl33062_0898.

Phylogenomic databases

eggNOGCOG0782.
KOK03624.
OMAITKVEWR.
OrthoDBEOG686NQ9.

Enzyme and pathway databases

BioCycHPY:HP0866-MONOMER.

Family and domain databases

Gene3D1.10.287.180. 1 hit.
3.10.50.30. 1 hit.
HAMAPMF_00105. GreA_GreB.
InterProIPR018151. TF_GreA/GreB_CS.
IPR006359. Tscrpt_elong_fac_GreA.
IPR028624. Tscrpt_elong_fac_GreA/B.
IPR001437. Tscrpt_elong_fac_GreA/B_C.
IPR023459. Tscrpt_elong_fac_GreA/B_fam.
IPR022691. Tscrpt_elong_fac_GreA/B_N.
[Graphical view]
PfamPF01272. GreA_GreB. 1 hit.
PF03449. GreA_GreB_N. 1 hit.
[Graphical view]
PIRSFPIRSF006092. GreA_GreB. 1 hit.
SUPFAMSSF46557. SSF46557. 1 hit.
TIGRFAMsTIGR01462. greA. 1 hit.
PROSITEPS00829. GREAB_1. 1 hit.
PS00830. GREAB_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGREA_HELPY
AccessionPrimary (citable) accession number: P64275
Secondary accession number(s): P55978
Entry history
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: July 9, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Helicobacter pylori

Helicobacter pylori (strain 26695): entries and gene names