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Protein

Aminomethyltransferase

Gene

gcvT

Organism
Salmonella typhi
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The glycine cleavage system catalyzes the degradation of glycine.UniRule annotation

Catalytic activityi

[Protein]-S8-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminotransferase, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
AminomethyltransferaseUniRule annotation (EC:2.1.2.10UniRule annotation)
Alternative name(s):
Glycine cleavage system T proteinUniRule annotation
Gene namesi
Name:gcvTUniRule annotation
Ordered Locus Names:STY3211, t2973
OrganismiSalmonella typhi
Taxonomic identifieri90370 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000002670 Componenti: Chromosome
  • UP000000541 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001225911 – 364AminomethyltransferaseAdd BLAST364

Interactioni

Subunit structurei

The glycine cleavage system is composed of four proteins: P, T, L and H.UniRule annotation

Protein-protein interaction databases

STRINGi220341.STY3211

Structurei

3D structure databases

ProteinModelPortaliP64223
SMRiP64223
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GcvT family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D43 Bacteria
COG0404 LUCA
HOGENOMiHOG000239381
KOiK00605
OMAiMPVQYPA

Family and domain databases

Gene3Di3.30.1360.120, 2 hits
HAMAPiMF_00259 GcvT, 1 hit
InterProiView protein in InterPro
IPR006223 GCS_T
IPR022903 GCS_T_bac
IPR028896 GCST/YgfZ/DmdA
IPR013977 GCV_T_C
IPR006222 GCV_T_N
IPR029043 GcvT/YgfZ_C
IPR027266 TrmE/GcvT_dom1
PfamiView protein in Pfam
PF01571 GCV_T, 1 hit
PF08669 GCV_T_C, 1 hit
PIRSFiPIRSF006487 GcvT, 1 hit
SUPFAMiSSF101790 SSF101790, 1 hit
TIGRFAMsiTIGR00528 gcvT, 1 hit

Sequencei

Sequence statusi: Complete.

P64223-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQQTPLYEQ HTLCGARMVD FHGWMMPLHY GSQLDEHHAV RTDAGMFDVS
60 70 80 90 100
HMTIVDLHGS RTREFLRYLL ANDVAKLTKT GKALYSGMLN ASGGVIDDLI
110 120 130 140 150
VYYFTEDFFR LVVNSATREK DLSWITQHAE PYAIDITVRD DLSLIAVQGP
160 170 180 190 200
NAQEKAATLF TDQQRHAVEG MKPFFGVQAG DLFIATTGYT GEAGYEIAMP
210 220 230 240 250
NEKAADFWRA LVEAGVKPCG LGARDTLRLE AGMNLYGQEM DEGISPLAAN
260 270 280 290 300
MGWTIAWEPA DRDFIGREAL EMQREKGHEQ LVGLVMTEKG VLRNELPVRF
310 320 330 340 350
TDAQGNQQEG IITSGTFSPT LGYSIALARV PAGIGETAIV QIRNREMPVK
360
VTKPVFVRNG KAVA
Length:364
Mass (Da):40,217
Last modified:October 11, 2004 - v1
Checksum:i5CCF54BC8EE86EA7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL513382 Genomic DNA Translation: CAD02885.1
AE014613 Genomic DNA Translation: AAO70525.1
RefSeqiNP_457453.1, NC_003198.1
WP_000068738.1, NZ_PHKG01000024.1

Genome annotation databases

EnsemblBacteriaiAAO70525; AAO70525; t2973
CAD02885; CAD02885; CAD02885
GeneIDi1249495
KEGGistt:t2973
sty:STY3211
PATRICifig|220341.7.peg.3270

Similar proteinsi

Entry informationi

Entry nameiGCST_SALTI
AccessioniPrimary (citable) accession number: P64223
Secondary accession number(s): Q8XG67
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: March 28, 2018
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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