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Protein

Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B

Gene

gatB

Organism
Brucella suis biovar 1 (strain 1330)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).UniRule annotation

Catalytic activityi

ATP + L-glutamyl-tRNA(Gln) + L-glutamine = ADP + phosphate + L-glutaminyl-tRNA(Gln) + L-glutamate.UniRule annotation
ATP + L-aspartyl-tRNA(Asn) + L-glutamine = ADP + phosphate + L-asparaginyl-tRNA(Asn) + L-glutamate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit BUniRule annotation (EC:6.3.5.-UniRule annotation)
Short name:
Asp/Glu-ADT subunit BUniRule annotation
Gene namesi
Name:gatBUniRule annotation
Ordered Locus Names:BR0899, BS1330_I0895
OrganismiBrucella suis biovar 1 (strain 1330)
Taxonomic identifieri204722 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000007104 Componenti: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 500500Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit BPRO_0000148771Add
BLAST

Interactioni

Subunit structurei

Heterotrimer of A, B and C subunits.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliP64198.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GatB/GatE family. GatB subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0064.
HOGENOMiHOG000223743.
KOiK02434.
OMAiESADYRY.
OrthoDBiEOG6RJV5B.

Family and domain databases

HAMAPiMF_00121. GatB.
InterProiIPR004413. Apn/Gln-ADT_bsu.
IPR017959. Asn/Gln-tRNA_amidoTrfase_suB/E.
IPR006075. Asn/Gln-tRNA_Trfase_suB/E_cat.
IPR018027. Asn/Gln_amidotransferase.
IPR003789. Asn/Gln_tRNA_amidoTrfrase-rel.
IPR017958. Gln-tRNA_amidoTrfase_suB_CS.
[Graphical view]
PANTHERiPTHR11659. PTHR11659. 1 hit.
PfamiPF02934. GatB_N. 1 hit.
PF02637. GatB_Yqey. 1 hit.
[Graphical view]
SMARTiSM00845. GatB_Yqey. 1 hit.
[Graphical view]
SUPFAMiSSF89095. SSF89095. 1 hit.
TIGRFAMsiTIGR00133. gatB. 1 hit.
PROSITEiPS01234. GATB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P64198-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSIIDTRTPE PKRFISGATG DWEVVIGMEV HAQVTSESKL FSGASTAFGA
60 70 80 90 100
EPNSNVSLVD AAMPGMLPVI NLECVRQAVR TGIGLNAQIN LKSVFDRKNY
110 120 130 140 150
FYPDLPQGYQ ISQFKQPIVG EGKIMISVGP DNKGQFEDVE IGIERLHLEQ
160 170 180 190 200
DAGKSMHDQH PTMSYVDLNR SGVALMEIVS KPDLRSSDEA RAYLTKLRTI
210 220 230 240 250
VRYLGTCDGN MDEGSMRADV NVSVRRPGGE FGTRCEIKNV NSIRFVGQAI
260 270 280 290 300
EYEARRQIAI LEDGGVIDQE TRLFDPVKGE TRSMRSKEEA HDYRYFPDPD
310 320 330 340 350
LLPLEFDQAF VDALAAKLPE LPDVKKQRLV ETLGISVYDA SILVTEKAIA
360 370 380 390 400
DYYEAVAEGR DGKAAANWVI NDLLGALNKA GKDIEESPIS PAQLGAIIDL
410 420 430 440 450
IKEGTISGKI AKDLFEIVWN EGGDPKKLVE ERGMKQVTDT GAIEKAVDDV
460 470 480 490 500
IAANPDKVEQ AKAKPTLAGW FVGQVMKATG GKANPQAVNE LVKSKLGIEE
Length:500
Mass (Da):54,714
Last modified:October 11, 2004 - v1
Checksum:iFEBA3251275BE195
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014291 Genomic DNA. Translation: AAN29827.1.
CP002997 Genomic DNA. Translation: AEM18244.1.
RefSeqiWP_002964030.1. NZ_KN046804.1.

Genome annotation databases

EnsemblBacteriaiAAN29827; AAN29827; BR0899.
AEM18244; AEM18244; BS1330_I0895.
GeneIDi3788721.
KEGGibms:BR0899.
bsi:BS1330_I0895.
PATRICi17790106. VBIBruSui107850_0913.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014291 Genomic DNA. Translation: AAN29827.1.
CP002997 Genomic DNA. Translation: AEM18244.1.
RefSeqiWP_002964030.1. NZ_KN046804.1.

3D structure databases

ProteinModelPortaliP64198.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN29827; AAN29827; BR0899.
AEM18244; AEM18244; BS1330_I0895.
GeneIDi3788721.
KEGGibms:BR0899.
bsi:BS1330_I0895.
PATRICi17790106. VBIBruSui107850_0913.

Phylogenomic databases

eggNOGiCOG0064.
HOGENOMiHOG000223743.
KOiK02434.
OMAiESADYRY.
OrthoDBiEOG6RJV5B.

Family and domain databases

HAMAPiMF_00121. GatB.
InterProiIPR004413. Apn/Gln-ADT_bsu.
IPR017959. Asn/Gln-tRNA_amidoTrfase_suB/E.
IPR006075. Asn/Gln-tRNA_Trfase_suB/E_cat.
IPR018027. Asn/Gln_amidotransferase.
IPR003789. Asn/Gln_tRNA_amidoTrfrase-rel.
IPR017958. Gln-tRNA_amidoTrfase_suB_CS.
[Graphical view]
PANTHERiPTHR11659. PTHR11659. 1 hit.
PfamiPF02934. GatB_N. 1 hit.
PF02637. GatB_Yqey. 1 hit.
[Graphical view]
SMARTiSM00845. GatB_Yqey. 1 hit.
[Graphical view]
SUPFAMiSSF89095. SSF89095. 1 hit.
TIGRFAMsiTIGR00133. gatB. 1 hit.
PROSITEiPS01234. GATB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1330.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1330.

Entry informationi

Entry nameiGATB_BRUSU
AccessioniPrimary (citable) accession number: P64198
Secondary accession number(s): G0K9C7, Q8YGT9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: July 22, 2015
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella suis
    Brucella suis (strain 1330): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.