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P64184 (GLPD2_MYCTU) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glycerol-3-phosphate dehydrogenase 2
EC=1.1.5.3
Gene names
Name:glpD2
Ordered Locus Names:Rv3302c, MT3401
ORF Names:MTCI418A.04c, MTV016.01c
OrganismMycobacterium tuberculosis
Taxonomic identifier1773 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length585 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.

Cofactor

FAD By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

Ontologies

Keywords
   Biological processGlycerol metabolism
   Cellular componentCytoplasm
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processglycerol-3-phosphate metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentglycerol-3-phosphate dehydrogenase complex

Inferred from electronic annotation. Source: InterPro

plasma membrane

Inferred from direct assay. Source: MTBBASE

   Molecular functionsn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 585585Glycerol-3-phosphate dehydrogenase 2
PRO_0000126102

Regions

Nucleotide binding37 – 6529FAD By similarity

Sequences

Sequence LengthMass (Da)Tools
P64184 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: 760C15F7E75BB69F

FASTA58562,778
        10         20         30         40         50         60 
MSNPIQAPDG GQGWPAAALG PAQRAVAWKR LGTEQFDVVV IGGGVVGSGC ALDAATRGLK 

        70         80         90        100        110        120 
VALVEARDLA SGTSSRSSKM FHGGLRYLEQ LEFGLVREAL YERELSLTTL APHLVKPLPF 

       130        140        150        160        170        180 
LFPLTKRWWE RPYIAAGIFL YDRLGGAKSV PAQRHFTRAG ALRLSPGLKR SSLIGGIRYY 

       190        200        210        220        230        240 
DTVVDDARHT MTVARTAAHY GAVVRCSTQV VALLREGDRV IGVGVRDSEN GAVAEVRGHV 

       250        260        270        280        290        300 
VVNATGVWTD EIQALSKQRG RFQVRASKGV HVVVPRDRIV SDVAMILRTE KSVMFVIPWG 

       310        320        330        340        350        360 
SHWIIGTTDT DWNLDLAHPA ATKADIDYIL GTVNAVLATP LTHADIDGVY AGLRPLLAGE 

       370        380        390        400        410        420 
SDDTSKLSRE HAVAVPAAGL VAIAGGKYTT YRVMAADAID AAVQFIPARV APSITEKVSL 

       430        440        450        460        470        480 
LGADGYFALV NQAEHVGALQ GLHPYRVRHL LDRYGSLISD VLAMAASDPS LLSPITEAPG 

       490        500        510        520        530        540 
YLKVEAAYAA AAEGALHLED ILARRMRISI EYPHRGVDCA REVAEVVAPV LGWTAADIDR 

       550        560        570        580 
EVANYMARVE AEVLSQAQPD DVSADMLRAS APEARAEILE PVPLD

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BX842582 Genomic DNA. Translation: CAB09447.1.
AE000516 Genomic DNA. Translation: AAK47744.1.
PIRH70533.
RefSeqNP_217819.1. NC_000962.2.
NP_337930.1. NC_002755.2.

3D structure databases

ProteinModelPortalP64184.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000000367; EBMYCP00000000367; EBMYCG00000000367.
EBMYCT00000071414; EBMYCP00000069473; EBMYCG00000071409.
GeneID887211.
926639.
GenomeReviewsGene locus MT3401 in contig AE000516_GR.
Gene locus Rv3302c in contig AL123456_GR.
KEGGmtc:MT3401.
mtu:Rv3302c.
PATRIC18129230. VBIMycTub22151_3711.
TIGRMT3401.

Organism-specific databases

TubercuListRv3302c.

Phylogenomic databases

GeneTreeEBGT00050000015584.
HOGENOMHBG720894.
OMAEWMLLPI.
PhylomeDBP64184.
ProtClustDBCLSK872167.

Family and domain databases

InterProIPR006076. FAD-dep_OxRdtase.
IPR000447. G3P_DH_FAD-dep.
[Graphical view]
KOK00111.
PfamPF01266. DAO. 1 hit.
[Graphical view]
PRINTSPR01001. FADG3PDH.
PROSITEPS00977. FAD_G3PDH_1. 1 hit.
PS00978. FAD_G3PDH_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGLPD2_MYCTU
AccessionPrimary (citable) accession number: P64184
Secondary accession number(s): O07168
Entry history
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: January 25, 2012
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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