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Protein

Glycerol-3-phosphate dehydrogenase 1

Gene

glpD1

Organism
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.

Cofactori

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi28 – 5629FADBy similarityAdd
BLAST

GO - Molecular functioni

  1. sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity Source: UniProtKB-EC

GO - Biological processi

  1. glycerol-3-phosphate metabolic process Source: InterPro
  2. glycerol metabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Glycerol metabolism

Keywords - Ligandi

FAD, Flavoprotein

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase 1 (EC:1.1.5.3)
Gene namesi
Name:glpD1
Synonyms:glpD
Ordered Locus Names:Mb2273c
OrganismiMycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Taxonomic identifieri233413 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
ProteomesiUP000001419 Componenti: Chromosome

Subcellular locationi

  1. Cytoplasm By similarity

GO - Cellular componenti

  1. glycerol-3-phosphate dehydrogenase complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 516516Glycerol-3-phosphate dehydrogenase 1PRO_0000126101Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi233413.Mb2273c.

Structurei

3D structure databases

ProteinModelPortaliP64183.
SMRiP64183. Positions 27-498.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0578.
HOGENOMiHOG000004813.
KOiK00111.
OMAiSREHAVT.
OrthoDBiEOG651SR7.

Family and domain databases

InterProiIPR006076. FAD-dep_OxRdtase.
IPR000447. G3P_DH_FAD-dep.
[Graphical view]
PfamiPF01266. DAO. 1 hit.
[Graphical view]
PRINTSiPR01001. FADG3PDH.
PROSITEiPS00977. FAD_G3PDH_1. 1 hit.
PS00978. FAD_G3PDH_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P64183-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLMPHSAALN AARRSADLTA LADGGALDVI VIGGGITGVG IALDAATRGL
60 70 80 90 100
TVALVEKHDL AFGTSRWSSK LVHGGLRYLA SGNVGIARRS AVERGILMTR
110 120 130 140 150
NAPHLVHAMP QLVPLLPSMG HTKRALVRAG FLAGDALRVL AGTPAATLPR
160 170 180 190 200
SRRIPASRVV EIAPTVRRDG LDGGLLAYDG QLIDDARLVM AVARTAAQHG
210 220 230 240 250
ARILTYVGAS NVTGTSVELT DRRTRQSFAL SARAVINAAG VWAGEIDPSL
260 270 280 290 300
RLRPSRGTHL VFDAKSFANP TAALTIPIPG ELNRFVFAMP EQLGRIYLGL
310 320 330 340 350
TDEDAPGPIP DVPQPSSEEI TFLLDTVNTA LGTAVGTKDV IGAYAGLRPL
360 370 380 390 400
IDTGGAGVQG RTADVSRDHA VFESPSGVIS VVGGKLTEYR YMAEDVLNRA
410 420 430 440 450
ITLRHLRAAK CRTRNLPLIG APANPGPAPG SGAGLPESLV ARYGAEAANV
460 470 480 490 500
AAAATCERPT EPVADGIDVT RAEFEYAVTH EGALDVDDIL DRRTRIGLVP
510
RDRERVVAVA KEFLSR
Length:516
Mass (Da):54,176
Last modified:October 11, 2004 - v1
Checksum:i164A136FEEB402E6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX248333 Genomic DNA. Translation: CDO43530.1.
RefSeqiNP_855922.1. NC_002945.3.

Genome annotation databases

EnsemblBacteriaiCDO43530; CDO43530; Mb2273c.
GeneIDi1091414.
KEGGimbo:Mb2273c.
PATRICi18006698. VBIMycBov88188_2494.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX248333 Genomic DNA. Translation: CDO43530.1.
RefSeqiNP_855922.1. NC_002945.3.

3D structure databases

ProteinModelPortaliP64183.
SMRiP64183. Positions 27-498.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi233413.Mb2273c.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCDO43530; CDO43530; Mb2273c.
GeneIDi1091414.
KEGGimbo:Mb2273c.
PATRICi18006698. VBIMycBov88188_2494.

Phylogenomic databases

eggNOGiCOG0578.
HOGENOMiHOG000004813.
KOiK00111.
OMAiSREHAVT.
OrthoDBiEOG651SR7.

Family and domain databases

InterProiIPR006076. FAD-dep_OxRdtase.
IPR000447. G3P_DH_FAD-dep.
[Graphical view]
PfamiPF01266. DAO. 1 hit.
[Graphical view]
PRINTSiPR01001. FADG3PDH.
PROSITEiPS00977. FAD_G3PDH_1. 1 hit.
PS00978. FAD_G3PDH_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-935 / AF2122/97.

Entry informationi

Entry nameiGLPD1_MYCBO
AccessioniPrimary (citable) accession number: P64183
Secondary accession number(s): Q10502, X2BK71
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: April 1, 2015
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.