P63933 (DGTL1_BRUME) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxyguanosinetriphosphate triphosphohydrolase-like protein

Gene names

Ordered Locus Names:

BMEI1090

Organism

Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) [Complete proteome] [HAMAP]

Taxonomic identifier

224914 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella melitensis › Brucella melitensis bv. 1

Protein attributes

Sequence length	402 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the dGTPase family. Type 2 subfamily.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	GTP metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	dGTPase activity Inferred from electronic annotation. Source: InterPro magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoric diester hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 402	402	Deoxyguanosinetriphosphate triphosphohydrolase-like protein HAMAP-Rule MF_01212		PRO_0000205296

Sequences

	Sequence		Length	Mass (Da)
	P63933 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: 283F7B5E0FE206D4	FASTA	402	45,727
	10 20 30 40 50 60 MSLEGIGFGY RERAPYASNP AFSRGRLVPE PESPTRTPFQ RDRDRIIHST AFRRLKHKTQ 70 80 90 100 110 120 VFIAHEGDHY RTRLTHTIEV AQIARALARA LRLDEDLAEA VALVHDFGHT PFGHTGEDAL 130 140 150 160 170 180 NERMKNFGGF DHNAQSLRIV TKLEHRYADF DGLNLSWETL EGLVKHNGPL LGPYAAHPDI 190 200 210 220 230 240 PVPQPILDFN ARYDLELSRF ASLEAQCAAI ADDIAYNAHD IDDGLRAGLL TLESLDEVPL 250 260 270 280 290 300 AKRLLDIVRT RYPNLDPVRT GHELVRRQIT IMVEDVIEEA QRRLASARPG TMEDVHNQPR 310 320 330 340 350 360 ALVGFSDAMR AEEKVLKRFL FKNLYFHESV VVRRHAADRI VQDLFDACFT DPSLMPDEWR 370 380 390 400 LGCEALDKAA LARRVADYLA GMTDNYAVRE HRRLFDRTPD LA

References

[1]

"The genome sequence of the facultative intracellular pathogen Brucella melitensis." DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T., Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G., Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E., Selkov E. , Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J., Haselkorn R., Kyrpides N.C., Overbeek R. Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 16M / ATCC 23456 / NCTC 10094.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE008917 Genomic DNA. Translation: AAL52271.1.
PIR	AD3388.
RefSeq	NP_540007.1. NC_003317.1.
3D structure databases
ProteinModelPortal	P63933.
ModBase	Search...
Protein-protein interaction databases
STRING	224914.BMEI1090.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAL52271; AAL52271; BMEI1090.
GeneID	1196801.
KEGG	bme:BMEI1090.
PATRIC	17797848. VBIBruMel146950_0740.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000082148.
KO	K01129.
OMA	ERWRAPY.
ProtClustDB	PRK01286.
Family and domain databases
Gene3D	1.10.3210.10. 2 hits.
HAMAP	MF_01212. dGTPase_type2.
InterPro	IPR006261. dGTP_triP_hydro. IPR023023. dGTP_triP_hydro_type2. IPR003607. HD/PDEase_dom. IPR006674. HD_domain. IPR026875. PHydrolase_assoc_dom. IPR006675. Uncharacterised_HDIG. [Graphical view]
Pfam	PF01966. HD. 1 hit. PF13286. HD_assoc. 1 hit. [Graphical view]
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01353. dGTP_triPase. 1 hit. TIGR00277. HDIG. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DGTL1_BRUME

Accession

Primary (citable) accession number: P63933
Secondary accession number(s): Q8YGR8

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 11, 2004
Last sequence update:	October 11, 2004
Last modified:	May 1, 2013
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program