SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P63902

- DCD_ECO57

UniProt

P63902 - DCD_ECO57

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Deoxycytidine triphosphate deaminase
Gene
dcd, Z3233, ECs2872
Organism
Escherichia coli O157:H7
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

dCTP + H2O = dUTP + NH3.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. dCTP deaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. dUMP biosynthetic process Source: UniProtKB-UniPathway
  2. dUTP biosynthetic process Source: InterPro
  3. pyrimidine ribonucleotide biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Nucleotide metabolism

Enzyme and pathway databases

BioCyciECOL386585:GJFA-2835-MONOMER.
ECOO157:DCD-MONOMER.
UniPathwayiUPA00610; UER00665.

Names & Taxonomyi

Protein namesi
Recommended name:
Deoxycytidine triphosphate deaminase (EC:3.5.4.13)
Short name:
dCTP deaminase
Gene namesi
Name:dcd
Ordered Locus Names:Z3233, ECs2872
OrganismiEscherichia coli O157:H7
Taxonomic identifieri83334 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000000558: Chromosome, UP000002519: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 193193Deoxycytidine triphosphate deaminaseUniRule annotation
PRO_0000155986Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi155864.Z3233.

Structurei

3D structure databases

ProteinModelPortaliP63902.
SMRiP63902. Positions 1-193.

Family & Domainsi

Sequence similaritiesi

Belongs to the dCTP deaminase family.

Phylogenomic databases

eggNOGiCOG0717.
HOGENOMiHOG000228601.
KOiK01494.
OMAiRPGMMIG.
OrthoDBiEOG67DPKR.

Family and domain databases

Gene3Di2.70.40.10. 1 hit.
HAMAPiMF_00146. dCTP_deaminase.
InterProiIPR011962. dCTP_deam.
IPR029054. dUTPase-like.
IPR008180. dUTPase/dCTP_deaminase.
[Graphical view]
PfamiPF00692. dUTPase. 1 hit.
[Graphical view]
SUPFAMiSSF51283. SSF51283. 1 hit.
TIGRFAMsiTIGR02274. dCTP_deam. 1 hit.

Sequencei

Sequence statusi: Complete.

P63902-1 [UniParc]FASTAAdd to Basket

« Hide

MRLCDRDIEA WLDEGRLSIN PRPPVERING ATVDVRLGNK FRTFRGHTAA    50
FIDLSGPKDE VSAALDRVMS DEIVLDESEA FYLHPGELAL AVTLESVTLP 100
ADLVGWLDGR SSLARLGLMV HVTAHRIDPG WSGCIVLEFY NSGKLPLALR 150
PGMLIGALSF EPLSGPAARP YNRREDAKYR NQQGAVASRI DKD 193
Length:193
Mass (Da):21,251
Last modified:October 11, 2004 - v1
Checksum:iE0063139C04A4FC2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE005174 Genomic DNA. Translation: AAG57127.1.
BA000007 Genomic DNA. Translation: BAB36295.1.
PIRiC85833.
H90987.
RefSeqiNP_288573.1. NC_002655.2.
NP_310899.1. NC_002695.1.

Genome annotation databases

EnsemblBacteriaiAAG57127; AAG57127; Z3233.
BAB36295; BAB36295; BAB36295.
GeneIDi916917.
959524.
KEGGiece:Z3233.
ecs:ECs2872.
PATRICi18355128. VBIEscCol44059_2765.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE005174 Genomic DNA. Translation: AAG57127.1 .
BA000007 Genomic DNA. Translation: BAB36295.1 .
PIRi C85833.
H90987.
RefSeqi NP_288573.1. NC_002655.2.
NP_310899.1. NC_002695.1.

3D structure databases

ProteinModelPortali P63902.
SMRi P63902. Positions 1-193.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 155864.Z3233.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAG57127 ; AAG57127 ; Z3233 .
BAB36295 ; BAB36295 ; BAB36295 .
GeneIDi 916917.
959524.
KEGGi ece:Z3233.
ecs:ECs2872.
PATRICi 18355128. VBIEscCol44059_2765.

Phylogenomic databases

eggNOGi COG0717.
HOGENOMi HOG000228601.
KOi K01494.
OMAi RPGMMIG.
OrthoDBi EOG67DPKR.

Enzyme and pathway databases

UniPathwayi UPA00610 ; UER00665 .
BioCyci ECOL386585:GJFA-2835-MONOMER.
ECOO157:DCD-MONOMER.

Family and domain databases

Gene3Di 2.70.40.10. 1 hit.
HAMAPi MF_00146. dCTP_deaminase.
InterProi IPR011962. dCTP_deam.
IPR029054. dUTPase-like.
IPR008180. dUTPase/dCTP_deaminase.
[Graphical view ]
Pfami PF00692. dUTPase. 1 hit.
[Graphical view ]
SUPFAMi SSF51283. SSF51283. 1 hit.
TIGRFAMsi TIGR02274. dCTP_deam. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: O157:H7 / EDL933 / ATCC 700927 / EHEC.
  2. "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and genomic comparison with a laboratory strain K-12."
    Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K., Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.
    , Kuhara S., Shiba T., Hattori M., Shinagawa H.
    DNA Res. 8:11-22(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: O157:H7 / Sakai / RIMD 0509952 / EHEC.

Entry informationi

Entry nameiDCD_ECO57
AccessioniPrimary (citable) accession number: P63902
Secondary accession number(s): Q8X7L4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: June 11, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi