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P63857 (COX3_MYCBO) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome aa3 subunit 3
Cytochrome c oxidase polypeptide III
Gene names
Name:ctaE
Ordered Locus Names:Mb2216
OrganismMycobacterium bovis (strain ATCC BAA-935 / AF2122/97) [Complete proteome] [HAMAP]
Taxonomic identifier233413 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex

Protein attributes

Sequence length203 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Cell membrane; Multi-pass membrane protein.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Keywords
   Cellular componentCell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processaerobic electron transport chain

Inferred from electronic annotation. Source: InterPro

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functioncytochrome-c oxidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 203203Probable cytochrome c oxidase subunit 3
PRO_0000183881

Regions

Transmembrane30 – 5021Helical; Potential
Transmembrane71 – 9121Helical; Potential
Transmembrane96 – 11621Helical; Potential
Transmembrane143 – 16321Helical; Potential
Transmembrane179 – 19921Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
P63857 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: 70145380A05BD0C2

FASTA20322,420
        10         20         30         40         50         60 
MTSAVGTSGT AITSRVHSLN RPNMVSVGTI VWLSSELMFF AGLFAFYFSA RAQAGGNWPP 

        70         80         90        100        110        120 
PPTELNLYQA VPVTLVLIAS SFTCQMGVFA AERGDIFGLR RWYVITFLMG LFFVLGQAYE 

       130        140        150        160        170        180 
YRNLMSHGTS IPSSAYGSVF YLATGFHGLH VTGGLIAFIF LLVRTGMSKF TPAQATASIV 

       190        200 
VSYYWHFVDI VWIALFTVIY FIR 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX248341 Genomic DNA. Translation: CAD97069.1.
RefSeqNP_855865.1. NC_002945.3.

3D structure databases

ProteinModelPortalP63857.
SMRP63857. Positions 28-201.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING233413.Mb2216.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAD97069; CAD97069; Mb2216.
GeneID1091330.
KEGGmbo:Mb2216.
PATRIC18006572. VBIMycBov88188_2432.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1845.
HOGENOMHOG000086399.
KOK02276.
OMAYEFHELL.
OrthoDBEOG6SFPBZ.
ProtClustDBCLSK872023.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_MYCBO
AccessionPrimary (citable) accession number: P63857
Secondary accession number(s): Q10385
Entry history
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: April 16, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families