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P63809

- COAA_BRUSU

UniProt

P63809 - COAA_BRUSU

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Protein

Pantothenate kinase

Gene

coaA

Organism
Brucella suis biovar 1 (strain 1330)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (R)-pantothenate = ADP + (R)-4'-phosphopantothenate.UniRule annotation

Pathwayi

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi100 – 1078ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. pantothenate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. coenzyme A biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Coenzyme A biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00241; UER00352.

Names & Taxonomyi

Protein namesi
Recommended name:
Pantothenate kinaseUniRule annotation (EC:2.7.1.33UniRule annotation)
Alternative name(s):
Pantothenic acid kinaseUniRule annotation
Gene namesi
Name:coaAUniRule annotation
Ordered Locus Names:BR2087, BS1330_I2081
OrganismiBrucella suis biovar 1 (strain 1330)
Taxonomic identifieri204722 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000000824: Chromosome I, UP000007104: Chromosome I

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 322322Pantothenate kinasePRO_0000194422Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi204722.BR2087.

Structurei

3D structure databases

ProteinModelPortaliP63809.
SMRiP63809. Positions 12-322.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the prokaryotic pantothenate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1072.
HOGENOMiHOG000248571.
KOiK00867.
OMAiFNRSQWA.
OrthoDBiEOG62C9GX.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00215. Pantothen_kinase_1.
InterProiIPR027417. P-loop_NTPase.
IPR004566. PanK_bact.
IPR006083. PRK/URK.
[Graphical view]
PANTHERiPTHR10285:SF7. PTHR10285:SF7. 1 hit.
PfamiPF00485. PRK. 1 hit.
[Graphical view]
PIRSFiPIRSF000545. Pantothenate_kin. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00554. panK_bact. 1 hit.

Sequencei

Sequence statusi: Complete.

P63809-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MWEKVDQLTP SRYSPYRFFS AQEWAAFRAD TPLTLTYEEV KRLRSLGDPI
60 70 80 90 100
DLDEVRRIYL SLSRLLYAHV EASQLLFRQR QQFLNMEESY KTPFIIGVAG
110 120 130 140 150
SVAVGKSTMA RILKELLARW PSSPKVDLVT TDGFLYPNAV LREQNMMERK
160 170 180 190 200
GFPESYDIGA VLRFLSAIKA GMSRVRAPLY SHLSYDVLPG EYQIVDKPDI
210 220 230 240 250
LIFEGINVLQ VRDLPEDGKM VPFVSDFFDF SIYIDADPRL IHKWYIDRFM
260 270 280 290 300
RLRETAFRDP QSFFHRYSQL SQEAARSIAE GLWQNINLKN LNENILPTRP
310 320
RADLILRKGS DHLIEEVALR KI
Length:322
Mass (Da):37,477
Last modified:October 11, 2004 - v1
Checksum:iD3EFE78CC7FC7D0B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014291 Genomic DNA. Translation: AAN30977.1.
CP002997 Genomic DNA. Translation: AEM19394.1.
RefSeqiNP_699062.1. NC_004310.3.
YP_005616886.1. NC_017251.1.

Genome annotation databases

EnsemblBacteriaiAAN30977; AAN30977; BR2087.
AEM19394; AEM19394; BS1330_I2081.
GeneIDi1167790.
12137870.
KEGGibms:BR2087.
bsi:BS1330_I2081.
PATRICi17792607. VBIBruSui107850_2124.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014291 Genomic DNA. Translation: AAN30977.1 .
CP002997 Genomic DNA. Translation: AEM19394.1 .
RefSeqi NP_699062.1. NC_004310.3.
YP_005616886.1. NC_017251.1.

3D structure databases

ProteinModelPortali P63809.
SMRi P63809. Positions 12-322.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 204722.BR2087.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAN30977 ; AAN30977 ; BR2087 .
AEM19394 ; AEM19394 ; BS1330_I2081 .
GeneIDi 1167790.
12137870.
KEGGi bms:BR2087.
bsi:BS1330_I2081.
PATRICi 17792607. VBIBruSui107850_2124.

Phylogenomic databases

eggNOGi COG1072.
HOGENOMi HOG000248571.
KOi K00867.
OMAi FNRSQWA.
OrthoDBi EOG62C9GX.

Enzyme and pathway databases

UniPathwayi UPA00241 ; UER00352 .

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
HAMAPi MF_00215. Pantothen_kinase_1.
InterProi IPR027417. P-loop_NTPase.
IPR004566. PanK_bact.
IPR006083. PRK/URK.
[Graphical view ]
PANTHERi PTHR10285:SF7. PTHR10285:SF7. 1 hit.
Pfami PF00485. PRK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000545. Pantothenate_kin. 1 hit.
SUPFAMi SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00554. panK_bact. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1330.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1330.

Entry informationi

Entry nameiCOAA_BRUSU
AccessioniPrimary (citable) accession number: P63809
Secondary accession number(s): G0K935, Q8YE39
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: October 29, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella suis
    Brucella suis (strain 1330): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3