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P63809

- COAA_BRUSU

UniProt

P63809 - COAA_BRUSU

Protein

Pantothenate kinase

Gene

coaA

Organism
Brucella suis biovar 1 (strain 1330)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 66 (01 Oct 2014)
      Sequence version 1 (11 Oct 2004)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + (R)-pantothenate = ADP + (R)-4'-phosphopantothenate.UniRule annotation

    Pathwayi

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi100 – 1078ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. pantothenate kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. coenzyme A biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Coenzyme A biosynthesis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    UniPathwayiUPA00241; UER00352.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Pantothenate kinaseUniRule annotation (EC:2.7.1.33UniRule annotation)
    Alternative name(s):
    Pantothenic acid kinaseUniRule annotation
    Gene namesi
    Name:coaAUniRule annotation
    Ordered Locus Names:BR2087, BS1330_I2081
    OrganismiBrucella suis biovar 1 (strain 1330)
    Taxonomic identifieri204722 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000000824: Chromosome I, UP000007104: Chromosome I

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 322322Pantothenate kinasePRO_0000194422Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi204722.BR2087.

    Structurei

    3D structure databases

    ProteinModelPortaliP63809.
    SMRiP63809. Positions 12-322.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the prokaryotic pantothenate kinase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1072.
    HOGENOMiHOG000248571.
    KOiK00867.
    OMAiFNRSQWA.
    OrthoDBiEOG62C9GX.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00215. Pantothen_kinase_1.
    InterProiIPR027417. P-loop_NTPase.
    IPR004566. PanK_bact.
    IPR006083. PRK/URK.
    [Graphical view]
    PANTHERiPTHR10285:SF7. PTHR10285:SF7. 1 hit.
    PfamiPF00485. PRK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000545. Pantothenate_kin. 1 hit.
    SUPFAMiSSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00554. panK_bact. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P63809-1 [UniParc]FASTAAdd to Basket

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    MWEKVDQLTP SRYSPYRFFS AQEWAAFRAD TPLTLTYEEV KRLRSLGDPI    50
    DLDEVRRIYL SLSRLLYAHV EASQLLFRQR QQFLNMEESY KTPFIIGVAG 100
    SVAVGKSTMA RILKELLARW PSSPKVDLVT TDGFLYPNAV LREQNMMERK 150
    GFPESYDIGA VLRFLSAIKA GMSRVRAPLY SHLSYDVLPG EYQIVDKPDI 200
    LIFEGINVLQ VRDLPEDGKM VPFVSDFFDF SIYIDADPRL IHKWYIDRFM 250
    RLRETAFRDP QSFFHRYSQL SQEAARSIAE GLWQNINLKN LNENILPTRP 300
    RADLILRKGS DHLIEEVALR KI 322
    Length:322
    Mass (Da):37,477
    Last modified:October 11, 2004 - v1
    Checksum:iD3EFE78CC7FC7D0B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE014291 Genomic DNA. Translation: AAN30977.1.
    CP002997 Genomic DNA. Translation: AEM19394.1.
    RefSeqiNP_699062.1. NC_004310.3.
    YP_005616886.1. NC_017251.1.

    Genome annotation databases

    EnsemblBacteriaiAAN30977; AAN30977; BR2087.
    AEM19394; AEM19394; BS1330_I2081.
    GeneIDi1167790.
    12137870.
    KEGGibms:BR2087.
    bsi:BS1330_I2081.
    PATRICi17792607. VBIBruSui107850_2124.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE014291 Genomic DNA. Translation: AAN30977.1 .
    CP002997 Genomic DNA. Translation: AEM19394.1 .
    RefSeqi NP_699062.1. NC_004310.3.
    YP_005616886.1. NC_017251.1.

    3D structure databases

    ProteinModelPortali P63809.
    SMRi P63809. Positions 12-322.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 204722.BR2087.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAN30977 ; AAN30977 ; BR2087 .
    AEM19394 ; AEM19394 ; BS1330_I2081 .
    GeneIDi 1167790.
    12137870.
    KEGGi bms:BR2087.
    bsi:BS1330_I2081.
    PATRICi 17792607. VBIBruSui107850_2124.

    Phylogenomic databases

    eggNOGi COG1072.
    HOGENOMi HOG000248571.
    KOi K00867.
    OMAi FNRSQWA.
    OrthoDBi EOG62C9GX.

    Enzyme and pathway databases

    UniPathwayi UPA00241 ; UER00352 .

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00215. Pantothen_kinase_1.
    InterProi IPR027417. P-loop_NTPase.
    IPR004566. PanK_bact.
    IPR006083. PRK/URK.
    [Graphical view ]
    PANTHERi PTHR10285:SF7. PTHR10285:SF7. 1 hit.
    Pfami PF00485. PRK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000545. Pantothenate_kin. 1 hit.
    SUPFAMi SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00554. panK_bact. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 1330.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 1330.

    Entry informationi

    Entry nameiCOAA_BRUSU
    AccessioniPrimary (citable) accession number: P63809
    Secondary accession number(s): G0K935, Q8YE39
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 11, 2004
    Last sequence update: October 11, 2004
    Last modified: October 1, 2014
    This is version 66 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Brucella suis
      Brucella suis (strain 1330): entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3