Uncharacterized FtsW-like protein - Mycobacterium tuberculosis

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P63760 (FTSWL_MYCTU) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 45. History...

Clusters with 100%, 90%, 50% identity |

Documents (1) |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
Uncharacterized FtsW-like protein

Gene names

Name:	rodA
Ordered Locus Names:	Rv0017c, MT0020
ORF Names:	MTCY10H4.17c

Organism

Mycobacterium tuberculosis

Taxonomic identifier

1773 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length	469 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Subcellular location	Cell membrane; Multi-pass membrane protein By similarity.
Sequence similarities	Belongs to the SEDS family.

Ontologies

Keywords
Cellular component	Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	cell cycle Inferred from electronic annotation. Source: UniProtKB-KW cell division Inferred from direct assay. Source: MTBBASE cellular cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	protein binding Inferred from physical interaction. Source: MTBBASE
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 469

469

Uncharacterized FtsW-like protein

PRO_0000062710

Regions

Transmembrane

20 – 40

Helical; Potential

Transmembrane

50 – 70

Helical; Potential

Transmembrane

76 – 96

Helical; Potential

Transmembrane

115 – 135

Helical; Potential

Transmembrane

146 – 166

Helical; Potential

Transmembrane

183 – 203

Helical; Potential

Transmembrane

226 – 246

Helical; Potential

Transmembrane

248 – 264

Helical; Potential

Transmembrane

267 – 287

Helical; Potential

Transmembrane

312 – 332

Helical; Potential

Transmembrane

344 – 364

Helical; Potential

Transmembrane

386 – 406

Helical; Potential

Transmembrane

418 – 438

Helical; Potential

Sequences

Sequence

Length

Mass (Da)

Tools

P63760 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: F4DBB2AB46ED72BA
Show »

FASTA

469

50,611

        10         20         30         40         50         60 
MTTRLQAPVA VTPPLPTRRN AELLLLCFAA VITFAALLVV QANQDQGVPW DLTSYGLAFL 

        70         80         90        100        110        120 
TLFGSAHLAI RRFAPYTDPL LLPVVALLNG LGLVMIHRLD LVDNEIGEHR HPSANQQMLW 

       130        140        150        160        170        180 
TLVGVAAFAL VVTFLKDHRQ LARYGYICGL AGLVFLAVPA LLPAALSEQN GAKIWIRLPG 

       190        200        210        220        230        240 
FSIQPAEFSK ILLLIFFSAV LVAKRGLFTS AGKHLLGMTL PRPRDLAPLL AAWVISVGVM 

       250        260        270        280        290        300 
VFEKDLGASL LLYTSFLVVV YLATQRFSWV VIGLTLFAAG TLVAYFIFEH VRLRVQTWLD 

       310        320        330        340        350        360 
PFADPDGTGY QIVQSLFSFA TGGIFGTGLG NGQPDTVPAA STDFIIAAFG EELGLVGLTA 

       370        380        390        400        410        420 
ILMLYTIVII RGLRTAIATR DSFGKLLAAG LSSTLAIQLF IVVGGVTRLI PLTGLTTPWM 

       430        440        450        460 
SYGGSSLLAN YILLAILARI SHGARRPLRT RPRNKSPITA AGTEVIERV

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References

[1]

"Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence."
Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E., Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.

Barrell B.G.
Nature 393:537-544(1998) [PubMed: 9634230] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 25618 / H37Rv.

[2]

"Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains."
Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O., Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K., Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L., Delcher A., Utterback T.R.

Fraser C.M.
J. Bacteriol. 184:5479-5490(2002) [PubMed: 12218036] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CDC 1551 / Oshkosh.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX842572 Genomic DNA. Translation: CAB02437.1. AE000516 Genomic DNA. Translation: AAK44242.1.
PIR	G70699.
RefSeq	NP_214531.1. NC_000962.2. NP_334428.1. NC_002755.2.
3D structure databases
ProteinModelPortal	P63760.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000001585; EBMYCP00000001585; EBMYCG00000001585. EBMYCT00000072790; EBMYCP00000070849; EBMYCG00000072785.
GeneID	887075. 922468.
GenomeReviews	Gene locus MT0020 in contig AE000516_GR. Gene locus Rv0017c in contig AL123456_GR.
KEGG	mtc:MT0020. mtu:Rv0017c.
PATRIC	18121770. VBIMycTub22151_0021.
TIGR	MT0020.
Organism-specific databases
TubercuList	Rv0017c.
Phylogenomic databases
GeneTree	EBGT00050000015955.
HOGENOM	HBG729614.
OMA	AAILMLY.
PhylomeDB	P63760.
ProtClustDB	CLSK790195.
Family and domain databases
InterPro	IPR001182. Cell_cycle. IPR018365. Cell_cycle_FtsW-rel_CS. [Graphical view]
Pfam	PF01098. FTSW_RODA_SPOVE. 1 hit. [Graphical view]
PROSITE	PS00428. FTSW_RODA_SPOVE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

FTSWL_MYCTU

Accession

Primary (citable) accession number: P63760
Secondary accession number(s): P71587

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 11, 2004
Last sequence update:	October 11, 2004
Last modified:	January 25, 2012
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Molecule processing

Regions

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

Entry information

Relevant documents