Reviewed, UniProtKB/Swiss-Prot P63660 (ATPE_BRUME)

Names and origin

Protein names

Recommended name:
    ATP synthase epsilon chain
Alternative name(s):
    ATP synthase F1 sector epsilon subunit
    F-ATPase epsilon subunit

Gene names

Name:	atpC
Ordered Locus Names:	BMEI0252

Organism

Brucella melitensis [Complete proteome] [HAMAP]

Taxonomic identifier

29459 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	135 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Produces ATP from ADP in the presence of a proton gradient across the membrane. HAMAP MF_00530
Subunit structure	F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a, b and c. HAMAP MF_00530
Subcellular location	Cell inner membrane; Peripheral membrane protein By similarity.
Sequence similarities	Belongs to the ATPase epsilon chain family.

Ontologies

Keywords
Biological process	ATP synthesis Hydrogen ion transport Ion transport Transport
Cellular component	CF(1) Cell inner membrane Cell membrane Membrane
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	plasma membrane ATP synthesis coupled proton transport Inferred from electronic annotation. Source: HAMAP
Cellular component	extrinsic to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW proton-transporting ATP synthase complex, catalytic core F(1) Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP hydrogen ion transporting ATP synthase activity, rotational mechanism Inferred from electronic annotation. Source: HAMAP proton-transporting ATPase activity, rotational mechanism Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 135	135	ATP synthase epsilon chain HAMAP MF_00530		PRO_0000188109

Sequences

	Sequence		Length	Mass (Da)
	P63660-1 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: FF4512C4E9576C33	FASTA	135	14,482
	10 20 30 40 50 60 MAQAFQFELV SPERLLLSAQ VTEVVIPGSE GYLTALAGHS PLMTTIMPGV VSVKLADGKT 70 80 90 100 110 120 DSYVVFGGFA DITPQGCTVL AESATHVDDI DPADIQHRID HARKVLEDAS SNEHRTKAEI 130 FLHQLMTLQG AILPA

References

[1]

"The genome sequence of the facultative intracellular pathogen Brucella melitensis." DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T., Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G., Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E., Selkov E. , Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J., Haselkorn R., Kyrpides N.C., Overbeek R. Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002) [PubMed: 11756688] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 16M / ATCC 23456 / NCTC 10094 / Biotype 1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE008917 Genomic DNA. Translation: AAL51434.1.
PIR	AG3283.
RefSeq	NP_539170.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1195964.
GenomeReviews	Gene locus BMEI0252 in contig AE008917_GR.
KEGG	bme:BMEI0252.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	P63660.
OMA	HAPLITN
Enzyme and pathway databases
BioCyc	BMEL224914:BMEI0252-MON.
BRENDA	3.6.3.14. 277959.
Family and domain databases
HAMAP	MF_00530. [Tree]
InterPro	IPR001469. ATPase_F1-cplx_dsu/esu. IPR020546. ATPase_F1-cplx_dsu/esu_N. [Graphical view]
Gene3D	G3DSA:2.60.15.10. ATPase_F1_d/e. 1 hit.
PANTHER	PTHR13822. ATPase_F1_d/e. 1 hit.
Pfam	PF02823. ATP-synt_DE_N. 1 hit. [Graphical view]
ProDom	PD000944. ATPase_F1-cplx_dsu/esu. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR01216. ATP_synt_epsi. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ATPE_BRUME

Accession

Primary (citable) accession number: P63660
Secondary accession number(s): Q8YJ34

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 11, 2004
Last sequence update:	October 11, 2004
Last modified:	November 24, 2009
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)