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Protein

Probable succinyl-CoA:3-ketoacid coenzyme A transferase subunit A

Gene

scoA

Organism
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Succinyl-CoA + a 3-oxo acid = succinate + a 3-oxoacyl-CoA.

GO - Molecular functioni

  1. 3-oxoacid CoA-transferase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Probable succinyl-CoA:3-ketoacid coenzyme A transferase subunit A (EC:2.8.3.5)
Alternative name(s):
Succinyl-CoA:3-oxoacid CoA-transferase
Short name:
OXCT A
Gene namesi
Name:scoA
Ordered Locus Names:Mb2532c
OrganismiMycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Taxonomic identifieri233413 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
ProteomesiUP000001419: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 248248Probable succinyl-CoA:3-ketoacid coenzyme A transferase subunit APRO_0000157912Add
BLAST

Interactioni

Subunit structurei

Heterodimer of a subunit A and a subunit B.By similarity

Protein-protein interaction databases

STRINGi233413.Mb2532c.

Structurei

3D structure databases

ProteinModelPortaliP63649.
SMRiP63649. Positions 3-247.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni24 – 307CoA-bindingSequence Analysis

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1788.
HOGENOMiHOG000221244.
KOiK01028.
OMAiGANKEFA.
OrthoDBiEOG6HMXJG.

Family and domain databases

InterProiIPR012792. 3-oxoacid_CoA-transf_A.
IPR004165. CoA_trans_fam_I.
IPR004163. CoA_transf_BS.
[Graphical view]
PANTHERiPTHR13707. PTHR13707. 1 hit.
PfamiPF01144. CoA_trans. 1 hit.
[Graphical view]
SMARTiSM00882. CoA_trans. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02429. pcaI_scoA_fam. 1 hit.
PROSITEiPS01273. COA_TRANSF_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P63649-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDKVVATAAE AVADIANGSS LAVGGFGLCG IPEALIAALV DSGVTDLETV
60 70 80 90 100
SNNCGIDGVG LGLLLQHKRI RRTVSSYVGE NKEFARQFLA GELEVELTPQ
110 120 130 140 150
GTLAERLRAG GMGIPAFYTP AGVGTQVADG GLPWRYDASG GVAVVSPAKE
160 170 180 190 200
TREFDGVTYV LERGIRTDFA LVHAWQGDRH GNLMYRHAAA NFNPECASAG
210 220 230 240
RITIAEVEHL VEPGEIDPAT VHTPGVFVHR VVHVPNPAKK IERETVRQ
Length:248
Mass (Da):26,276
Last modified:October 11, 2004 - v1
Checksum:i81340193CC48EBD1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX248333 Genomic DNA. Translation: CDO43794.1.
RefSeqiNP_856177.1. NC_002945.3.

Genome annotation databases

GeneIDi1090568.
KEGGimbo:Mb2532c.
PATRICi18007295. VBIMycBov88188_2787.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX248333 Genomic DNA. Translation: CDO43794.1.
RefSeqiNP_856177.1. NC_002945.3.

3D structure databases

ProteinModelPortaliP63649.
SMRiP63649. Positions 3-247.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi233413.Mb2532c.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1090568.
KEGGimbo:Mb2532c.
PATRICi18007295. VBIMycBov88188_2787.

Phylogenomic databases

eggNOGiCOG1788.
HOGENOMiHOG000221244.
KOiK01028.
OMAiGANKEFA.
OrthoDBiEOG6HMXJG.

Family and domain databases

InterProiIPR012792. 3-oxoacid_CoA-transf_A.
IPR004165. CoA_trans_fam_I.
IPR004163. CoA_transf_BS.
[Graphical view]
PANTHERiPTHR13707. PTHR13707. 1 hit.
PfamiPF01144. CoA_trans. 1 hit.
[Graphical view]
SMARTiSM00882. CoA_trans. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02429. pcaI_scoA_fam. 1 hit.
PROSITEiPS01273. COA_TRANSF_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-935 / AF2122/97.

Entry informationi

Entry nameiSCOA_MYCBO
AccessioniPrimary (citable) accession number: P63649
Secondary accession number(s): O06167, X2BKZ9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: February 4, 2015
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.