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Protein

Glutamate racemase

Gene

murI

Organism
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Provides the (R)-glutamate required for cell wall biosynthesis.UniRule annotation

Catalytic activityi

L-glutamate = D-glutamate.UniRule annotation

Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei75Proton donor/acceptorUniRule annotation1
Active sitei185Proton donor/acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processCell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis

Enzyme and pathway databases

BioCyciMBOV233413:G1GT4-1428-MONOMER
UniPathwayiUPA00219

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate racemaseUniRule annotation (EC:5.1.1.3UniRule annotation)
Gene namesi
Name:murIUniRule annotation
Ordered Locus Names:BQ2027_MB1373
OrganismiMycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Taxonomic identifieri233413 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001419 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000954901 – 271Glutamate racemaseAdd BLAST271

Proteomic databases

PRIDEiP63636

Structurei

3D structure databases

ProteinModelPortaliP63636
SMRiP63636
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni12 – 13Substrate bindingUniRule annotation2
Regioni44 – 45Substrate bindingUniRule annotation2
Regioni76 – 77Substrate bindingUniRule annotation2
Regioni186 – 187Substrate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the aspartate/glutamate racemases family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000262396
OMAiVYGCTHY

Family and domain databases

HAMAPiMF_00258 Glu_racemase, 1 hit
InterProiView protein in InterPro
IPR015942 Asp/Glu/hydantoin_racemase
IPR001920 Asp/Glu_race
IPR018187 Asp/Glu_racemase_AS_1
IPR033134 Asp/Glu_racemase_AS_2
IPR004391 Glu_race
PANTHERiPTHR21198:SF2 PTHR21198:SF2, 1 hit
PfamiView protein in Pfam
PF01177 Asp_Glu_race, 1 hit
SUPFAMiSSF53681 SSF53681, 2 hits
TIGRFAMsiTIGR00067 glut_race, 1 hit
PROSITEiView protein in PROSITE
PS00923 ASP_GLU_RACEMASE_1, 1 hit
PS00924 ASP_GLU_RACEMASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

P63636-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSPLAPVGV FDSGVGGLTV ARAIIDQLPD EDIVYVGDTG NGPYGPLTIP
60 70 80 90 100
EIRAHALAIG DDLVGRGVKA LVIACNSASS ACLRDARERY QVPVVEVILP
110 120 130 140 150
AVRRAVAATR NGRIGVIGTR ATITSHAYQD AFAAARDTEI TAVACPRFVD
160 170 180 190 200
FVERGVTSGR QVLGLAQGYL EPLQRAEVDT LVLGCTHYPL LSGLIQLAMG
210 220 230 240 250
ENVTLVSSAE ETAKEVVRVL TEIDLLRPHD APPATRIFEA TGDPEAFTKL
260 270
AARFLGPVLG GVQPVHPSRI H
Length:271
Mass (Da):28,643
Last modified:October 11, 2004 - v1
Checksum:i29DE3CE67A27EEBA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LT708304 Genomic DNA Translation: SIT99976.1
RefSeqiNP_855027.1, NC_002945.3
WP_003406919.1, NC_002945.4

Genome annotation databases

EnsemblBacteriaiCDO42620; CDO42620; Mb1373
PATRICifig|233413.5.peg.1505

Similar proteinsi

Entry informationi

Entry nameiMURI_MYCBO
AccessioniPrimary (citable) accession number: P63636
Secondary accession number(s): A0A1R3XYF0, Q10626, X2BI28
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: May 23, 2018
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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