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Protein

Glutamate racemase

Gene

murI

Organism
Brucella suis biovar 1 (strain 1330)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Provides the (R)-glutamate required for cell wall biosynthesis.UniRule annotation

Catalytic activityi

L-glutamate = D-glutamate.UniRule annotation

Pathway: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei89 – 891Proton donor/acceptorUniRule annotation
Active sitei204 – 2041Proton donor/acceptorUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Cell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis

Enzyme and pathway databases

UniPathwayiUPA00219.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate racemaseUniRule annotation (EC:5.1.1.3UniRule annotation)
Gene namesi
Name:murIUniRule annotation
Ordered Locus Names:BR1195, BS1330_I1191
OrganismiBrucella suis biovar 1 (strain 1330)
Taxonomic identifieri204722 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000007104 Componenti: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 277277Glutamate racemasePRO_0000095458Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP63632.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni25 – 262Substrate bindingUniRule annotation
Regioni57 – 582Substrate bindingUniRule annotation
Regioni90 – 912Substrate bindingUniRule annotation
Regioni205 – 2062Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the aspartate/glutamate racemases family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0796.
HOGENOMiHOG000262397.
KOiK01776.
OMAiLDFFKPH.
OrthoDBiEOG6B6296.

Family and domain databases

Gene3Di3.40.50.1860. 1 hit.
HAMAPiMF_00258. Glu_racemase.
InterProiIPR015942. Asp/Glu/hydantoin_racemase.
IPR001920. Asp/Glu_race.
IPR018187. Asp/Glu_racemase_AS.
IPR004391. Glu_race.
[Graphical view]
PfamiPF01177. Asp_Glu_race. 1 hit.
[Graphical view]
SUPFAMiSSF53681. SSF53681. 2 hits.
TIGRFAMsiTIGR00067. glut_race. 1 hit.
PROSITEiPS00923. ASP_GLU_RACEMASE_1. 1 hit.
PS00924. ASP_GLU_RACEMASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P63632-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKAPAGSFP AKPTIAPERP ILVFDSGIGG LTVLREARVV MPDRRFVYIA
60 70 80 90 100
DDAGFPYGNW EEEALKRRII ELFGEFIANY DPEIAVIACN TASTLVLEDL
110 120 130 140 150
RRAYPSVPFV GTVPAIKPAA ERTSSGLVSV LATPGTVKRA YTRDLIQSFA
160 170 180 190 200
SRCHVRLVGA DGLAAIAEAH IRGESFDEAL VMAQIAPCFI EKDGKRTDIV
210 220 230 240 250
VLACTHYPFL VNVLRRLAPW PVDWLDPAEA IARRMKSLLP ARSDDDEFHS
260 270
QDDLAFFTSR KPDYAIRRLM QGFGLRF
Length:277
Mass (Da):30,708
Last modified:October 11, 2004 - v1
Checksum:iB946C8EA5DD039E6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014291 Genomic DNA. Translation: AAN30114.1.
CP002997 Genomic DNA. Translation: AEM18532.1.
RefSeqiNP_698199.1. NC_004310.3.
WP_002964323.1. NZ_KN046804.1.
YP_005616024.1. NC_017251.1.

Genome annotation databases

EnsemblBacteriaiAAN30114; AAN30114; BR1195.
AEM18532; AEM18532; BS1330_I1191.
GeneIDi3788813.
KEGGibms:BR1195.
bsi:BS1330_I1191.
PATRICi17790721. VBIBruSui107850_1214.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014291 Genomic DNA. Translation: AAN30114.1.
CP002997 Genomic DNA. Translation: AEM18532.1.
RefSeqiNP_698199.1. NC_004310.3.
WP_002964323.1. NZ_KN046804.1.
YP_005616024.1. NC_017251.1.

3D structure databases

ProteinModelPortaliP63632.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN30114; AAN30114; BR1195.
AEM18532; AEM18532; BS1330_I1191.
GeneIDi3788813.
KEGGibms:BR1195.
bsi:BS1330_I1191.
PATRICi17790721. VBIBruSui107850_1214.

Phylogenomic databases

eggNOGiCOG0796.
HOGENOMiHOG000262397.
KOiK01776.
OMAiLDFFKPH.
OrthoDBiEOG6B6296.

Enzyme and pathway databases

UniPathwayiUPA00219.

Family and domain databases

Gene3Di3.40.50.1860. 1 hit.
HAMAPiMF_00258. Glu_racemase.
InterProiIPR015942. Asp/Glu/hydantoin_racemase.
IPR001920. Asp/Glu_race.
IPR018187. Asp/Glu_racemase_AS.
IPR004391. Glu_race.
[Graphical view]
PfamiPF01177. Asp_Glu_race. 1 hit.
[Graphical view]
SUPFAMiSSF53681. SSF53681. 2 hits.
TIGRFAMsiTIGR00067. glut_race. 1 hit.
PROSITEiPS00923. ASP_GLU_RACEMASE_1. 1 hit.
PS00924. ASP_GLU_RACEMASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1330.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1330.

Entry informationi

Entry nameiMURI_BRUSU
AccessioniPrimary (citable) accession number: P63632
Secondary accession number(s): G0KAB6, Q8YHK2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: June 24, 2015
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella suis
    Brucella suis (strain 1330): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.