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Protein

Glutamate racemase

Gene

murI

Organism
Brucella suis biovar 1 (strain 1330)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Provides the (R)-glutamate required for cell wall biosynthesis.UniRule annotation

Catalytic activityi

L-glutamate = D-glutamate.UniRule annotation

Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei89Proton donor/acceptorUniRule annotation1
Active sitei204Proton donor/acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processCell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis

Enzyme and pathway databases

UniPathwayiUPA00219

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate racemaseUniRule annotation (EC:5.1.1.3UniRule annotation)
Gene namesi
Name:murIUniRule annotation
Ordered Locus Names:BR1195, BS1330_I1191
OrganismiBrucella suis biovar 1 (strain 1330)
Taxonomic identifieri204722 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000954581 – 277Glutamate racemaseAdd BLAST277

Structurei

3D structure databases

ProteinModelPortaliP63632
SMRiP63632
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni25 – 26Substrate bindingUniRule annotation2
Regioni57 – 58Substrate bindingUniRule annotation2
Regioni90 – 91Substrate bindingUniRule annotation2
Regioni205 – 206Substrate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the aspartate/glutamate racemases family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000262397
KOiK01776
OMAiVYGCTHY

Family and domain databases

HAMAPiMF_00258 Glu_racemase, 1 hit
InterProiView protein in InterPro
IPR015942 Asp/Glu/hydantoin_racemase
IPR001920 Asp/Glu_race
IPR018187 Asp/Glu_racemase_AS_1
IPR033134 Asp/Glu_racemase_AS_2
IPR004391 Glu_race
PANTHERiPTHR21198:SF2 PTHR21198:SF2, 1 hit
PfamiView protein in Pfam
PF01177 Asp_Glu_race, 1 hit
SUPFAMiSSF53681 SSF53681, 2 hits
TIGRFAMsiTIGR00067 glut_race, 1 hit
PROSITEiView protein in PROSITE
PS00923 ASP_GLU_RACEMASE_1, 1 hit
PS00924 ASP_GLU_RACEMASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

P63632-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKAPAGSFP AKPTIAPERP ILVFDSGIGG LTVLREARVV MPDRRFVYIA
60 70 80 90 100
DDAGFPYGNW EEEALKRRII ELFGEFIANY DPEIAVIACN TASTLVLEDL
110 120 130 140 150
RRAYPSVPFV GTVPAIKPAA ERTSSGLVSV LATPGTVKRA YTRDLIQSFA
160 170 180 190 200
SRCHVRLVGA DGLAAIAEAH IRGESFDEAL VMAQIAPCFI EKDGKRTDIV
210 220 230 240 250
VLACTHYPFL VNVLRRLAPW PVDWLDPAEA IARRMKSLLP ARSDDDEFHS
260 270
QDDLAFFTSR KPDYAIRRLM QGFGLRF
Length:277
Mass (Da):30,708
Last modified:October 11, 2004 - v1
Checksum:iB946C8EA5DD039E6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014291 Genomic DNA Translation: AAN30114.1
CP002997 Genomic DNA Translation: AEM18532.1
RefSeqiWP_002964323.1, NZ_KN046804.1

Genome annotation databases

EnsemblBacteriaiAAN30114; AAN30114; BR1195
AEM18532; AEM18532; BS1330_I1191
GeneIDi29593615
KEGGibms:BR1195
bsi:BS1330_I1191
PATRICifig|204722.21.peg.2284

Similar proteinsi

Entry informationi

Entry nameiMURI_BRUSU
AccessioniPrimary (citable) accession number: P63632
Secondary accession number(s): G0KAB6, Q8YHK2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: March 28, 2018
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella suis
    Brucella suis (strain 1330): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

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