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P63450 (ACPXL_BRUME) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Acyl carrier protein AcpXL
Gene names
Name:acpXL
Ordered Locus Names:BMEI1111
OrganismBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) [Complete proteome] [HAMAP]
Taxonomic identifier224914 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length93 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is involved in the transfer of long hydroxylated fatty acids to lipid A By similarity.

Pathway

Glycolipid biosynthesis; KDO(2)-lipid A biosynthesis.

Subcellular location

Cytoplasm By similarity.

Post-translational modification

4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group By similarity.

Sequence similarities

Contains 1 acyl carrier domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 9393Acyl carrier protein AcpXL
PRO_0000180237

Amino acid modifications

Modified residue371O-(pantetheine 4'-phosphoryl)serine By similarity

Sequences

Sequence LengthMass (Da)Tools
P63450 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: 3383710AADA51807

FASTA9310,361
        10         20         30         40         50         60 
MSSTFDKVAD IIAETSEIDR DTITPESHTI DDLGIDSLDF LDIVFAIDKA FGIKIPLEQW 

        70         80         90 
TQEVNEGKVP TEEYFVLKNL CAKIDELVAA KKG 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE008917 Genomic DNA. Translation: AAL52292.1.
PIRAI3390.
RefSeqNP_540028.1. NC_003317.1.

3D structure databases

ProteinModelPortalP63450.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING224914.BMEI1111.

Proteomic databases

PRIDEP63450.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAL52292; AAL52292; BMEI1111.
GeneID1196822.
KEGGbme:BMEI1111.
PATRIC17797802. VBIBruMel146950_0716.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000178184.
OMAMTATFDK.
OrthoDBEOG6MWNJM.
ProtClustDBPRK06508.

Enzyme and pathway databases

UniPathwayUPA00360.

Family and domain databases

Gene3D1.10.1200.10. 1 hit.
InterProIPR009081. Acyl_carrier_prot-like.
IPR006162. PPantetheine_attach_site.
[Graphical view]
PfamPF00550. PP-binding. 1 hit.
[Graphical view]
SUPFAMSSF47336. SSF47336. 1 hit.
PROSITEPS50075. ACP_DOMAIN. 1 hit.
PS00012. PHOSPHOPANTETHEINE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACPXL_BRUME
AccessionPrimary (citable) accession number: P63450
Secondary accession number(s): Q8YGP7
Entry history
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: February 19, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Brucella melitensis

Brucella melitensis (strain 16M): entries and gene names